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Formamidopyrimidine-DNA glycosylase H2TH domain
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Damaged DNA binding | Interacting selectively and non-covalently with damaged DNA. | ||
| Molecular function | DNA-(apurinic or apyrimidinic site) endonuclease activity | Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). | ||
| Biological process | Nucleotide-excision repair | A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). | ||
| Molecular function | Zinc ion binding | Interacting selectively and non-covalently with zinc (Zn) ions. | ||
| Molecular function | Hydrolase activity, hydrolyzing N-glycosyl compounds | Catalysis of the hydrolysis of any N-glycosyl bond. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: formamidopyrimidine-DNA glycosylase-like isoform X2 [Cicer arietinum] gi|502080701|ref|XP_004486650.1| | 18 | ||
| – | PREDICTED: formamidopyrimidine-DNA glycosylase-like isoform X1 [Cicer arietinum] gi|502080698|ref|XP_004486649.1| | 18 | ||
| – | Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.2 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|A0A151SPP2|A0A151SPP2_CAJCA Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500 | 19 | ||
| – | Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.2 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|G7II90|G7II90_MEDTR Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500 | 19 | ||
| – | Formamidopyrimidine-DNA glycosylase; TAIR: AT1G52500.1 MUTM homolog-1; Swiss-Prot: sp|O80358|FPG_ARATH Formamidopyrimidine-DNA glycosylase; TrEMBL-Plants: tr|A0A151SPP2|A0A151SPP2_CAJCA Formamidopyrimidine-DNA glycosylase; Found in the gene: LotjaGi3g1v0007500 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd08972 | CDD | 1 | 20.00 |