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| Field | Value |
|---|---|
| Gene ID | Lj3g3v0075800 |
| Transcript ID | Lj3g3v0075800.1 |
| Lotus japonicus genome version | MG20 v3.0 |
| Description | Lys-63-specific deubiquitinase BRCC36 [Medicago truncatula] gi|357455111|ref|XP_003597836.1| |
| Working Lj name | n.a. |
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | 1 | 160 | 160 | 1.90E-92 | – | |
| PANTHER | 1 | 160 | 160 | 1.90E-92 | – | |
| Pfam | 3 | 120 | 118 | 2.70E-24 | ||
| CDD | 3 | 367 | 365 | 1.06E-102 | ||
| SUPERFAMILY | 5 | 134 | 130 | 1.15E-15 | – | |
| SMART | 5 | 151 | 147 | 1.20E-16 | ||
| Gene3D | 6 | 136 | 131 | 1.60E-10 | – | |
| MobiDBLite | 172 | 212 | 41 | – | – | |
| PANTHER | 261 | 380 | 120 | 1.90E-92 | – | |
| PANTHER | 261 | 380 | 120 | 1.90E-92 | – | |
| Coils | 356 | 383 | 28 | – | – | |
| MobiDBLite | 389 | 432 | 44 | – | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Thiol-dependent ubiquitin-specific protease activity | Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. | ||
| Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | ||
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
| Cellular component | BRCA1-A complex | A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. | ||
| Biological process | Protein K63-linked deubiquitination | A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. | ||
| Cellular component | BRISC complex | A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains. |
Expression pattern of Lj3g3v0075800.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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A list of the top 25 highly co-expressed genes of Lj3g3v0075800.1, powered by CORGI.
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