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| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0417900 |
| Transcript ID | LotjaGi1g1v0417900.1 |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | DNA-3-methyladenine glycosylase, putative; TAIR: AT1G75090.1 DNA glycosylase superfamily protein; Swiss-Prot: sp|Q7VG78|GUAA_HELHP Probable GMP synthase [glutamine]-hydrolyzing]; TrEMBL-Plants: tr|A0A072VD87|A0A072VD87_MEDTR DNA-3-methyladenine glycosylase I; Found in the gene: LotjaGi1g1v0417900 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:91179354..91183026) extracted from Lotus japonicus Gifu genome v1.2.
CCTTTATGCCATTTACATACCTAAATTATAGCTGACCTTTAATTCGTTAGCTCCCTTGTATAACATTTGTGGCAGCGAGG CGAAGAGTAATTGATTCAAAGATAATCTCCTTATAATGCTTATTGGTGAAGAAAAAAAAAAGCACGTTAAGAAAACTTAT GTTATTATCGTGAGTCCGATCGTCTAATCAAAATGTTACATTTTTATTTAGCTTACATGTCAATGCTCATAGTCAACTAA TCATCATGTTTTACAAAAAATTATGGACCATTTCTTCTAATATGTATATAGGCATTGAATGGATGCTCATGAAACTAGTC TTCACAACATGACAATGACTTTGTTTTTGGTCAATAACAAGACAATGACTTGAAGGGTTTTTTGTTTTTATTTTGGGCCG TCCAGAAGGATTAAAAGGGAAGGCCCGGCCCATATGTTGGAGCGAGAATTCTGGAATGATGTAGATGGACATGGTCGTTG ATGGGTAGAATGGTGACATAGCCGTTGGTTACCGAACACCATTACATGGTGGTGGCCTTTGCTTTTGTCTTTGGATTCTT TTCCTTAACGGTAACCAACTCTCCAAACACACCAACACAACATTCACTCACACACACCCAATTCTTAACGTTTACCCAAC ACAACACATCAACAAGTGTGTGTGCCTCTGACTCTGACCCTTTGCCTACGCTTTCTTTTCTCCTACCCCATTTTCCTTCC CTATATTTCAGCCAAACCAAACACCGAAAACAAAGACAGTGAACTAAAACTTGCATTTCAAATACCGAAAATGCCCGCAG TTCACTCTTTCTCTAAACCGGCTGCTGAACCGCGAACCGGAATCGAAGAGGCCGCGAAACGCAAGAAGGAGAAGGAGAAC CTGCAGAAAAATCCGCAACAACAACAACAACAACAACGTCTGAGAAAGCAGGTAGTGCAGGAAATCTCTGACTCCATTGT TGTACGATGTAACAACGTGTCTTTGGACAGCACGTGCTCCTCGGATTCATGTTCCAGTAAGTCCATGTCGGTCAAAAAAG TCAACTCAACAACAAAGACCTCAAATGCAAGTGCAACTAGTAGGAGGAGGAACGCGAGGTGCACTGGGTTTAAGCCGGCG AGGGTTGTGCCGGATGCAGCTGCAGTGTCTCCGCCTTCCAACGCCTCAGCACCGCCCAAGAAGTGTGATTGGATCACACC TAATTCCGGTAATTGGGCCTGCACCGTATCTTTTTTTTTTTATGTCTGAACTCTGAAGTCTAAACCACTCACCTCTCACC GCTGCCATGATTTTTTAATGTGAATCGATGCCTCTAAAAAATTGTACTATTAAATACTATTTAATCTTAGGTATTTTTCT TTTATTAAATTACACTTTGTGCCTTTTTCATGAATTTACATTTTGGCTTTTGGTTTGGTGTTCATGGCCCTATTGGAGGA GCTTATTTTCATATTGACTAAAGGTATCTCAAAGTCACTAGCTCAGCGTATGGTCCTGTTTAGAAAAGCTTATTTGATCC TGATCGTATAAGCGCTTATGTCAATGTTTGGGAGAGCTTATGTAAACAACTTATCATAAATTGTTTTGAGCTTATGTAAA AAATTTACCATAAGTTGTTTTGAGCTTATTCAACAAATAGCTTATGAACAAACGCTTATGTCATAAGAGATCATCGTTTG AAAAAGCTTATTTGAGCTTATCTGATAGCATAAGCGCTTATGTGAGTGTTTGGTGGCCATAAGTTGTTTTGAGCTTAGCT TATTTTCGATTTATTTCAATAAAAAATTTAAAATAGCTTATGAATAAGCGCTTATGTTATAAGCGCGACCATAAGCGCTT AATTAAGCTATTTTTCCATTAGGCGAGCTTATCTCACATCATAACATAAAAAGTTATATAAATAGCTTATAATACTTATA AATTGTTTTGAGCTTATGCATATGCTATTTTCTTCTCATTTCAATTAGTTTCTTAACTTAGCTTAAAAATAATGGGTATG TTTATTGACATAAATGCTCAATTAACCAGTTTAGCCAAATGCATATATCTAGATTTTTTTGGTTCGTAATTTCCAATATA GTAATATACTCTATTTATGGGATGGGATTGGAAACTTCATTTTTGGCAAAGGATGCTGCCAATGTGCATATTACCCCACT GGATAGGATTGCCTCACTGAGAAATGCTATTTCATTCTTTACAGACCCACTGTATAGTGCTTTCCATGATGAAGAATGGG GTGTTCCAGTCGTCCATGATGATAGAAAGCTATTTGAGCTTCTAGTCTTCTCACAAGCATTAGCAGAACACACTTGGCCA TCAATTCTTAGCCACAGAGACATGTTCAGGCATGTCCATCTCTAAATCTACTAATAGTTTTTTAAAAGCATGACACTTAA CATGTTATTTGACTATGATTATTTGATATCTTATAGGAAGCTTTTTGAAAACTTTGCTCCATCGTCAATTGCTCAGTTTA CTGAGAAGGAGTTGCTAACACCGAAAATAAACGGCAAGCCATTGTTATCAGAACCAAAGCTCCGCGCCATTGTCGAAAAT GCTAAACAATTACTTAAGGTAGCTTCAAAACTAATGCTGTGTTGAAACCCTTTACAATTAATTTTGAGACCGGAATCAAT TCTCGGGAGAAGCTTCTATAAATAGCTTCTCACGAGTCTCATAATTGATTATGATGAAAGAAAATATGATCCAAACATGC TAATAATATGTTTAAATTTATGTGAGTTGAAATTTGAAGATAGGAAAAAATTGAAAATAACCTTGATTGGGTCAACCGCC AACATAAATGCATTCCAAACTCACATGGCCATGATTTTTCCTTTTACAGGTCCAGCAGGAGTTTGGTTCATTCAGCAATT ATTGCTGGAGATTTGTTAGCCACAAACCAATAAGAAATGAATTTCGGTATGGACGACAAGTACCTGTGAAGACTCCAAAA GCAGAACTCATTAGCAAGGACATGATGCGGAGGGGTTTCCAATGTGTGGGACCAACGGTAGTTTATTCATTCATGCAAGT AGCAGGACTCGTAAATGATCACCTAGTAACATGTTTCAGGTTCCATGAATGCAGCAATGTGACTCTCAAAAACGAATTCA AAACAGAGGTTAAGGAGAAAAAGGTAGAAAATGAAACTGTGAATTTGACAAAGATTCAGTGACTCAACTGGAGGAGAGGT TCCAAGACATGGGGTCTCCATTGTGCTACTATCTCTTAATATACTTTAGGCTACAAGCTCATTGTTTCTTAATCTGTGTG TATGTTAATGCCACCTAACCTAACCATAAAATAATAGGTCTTATCTTGTTCTTTGAAGCTCCCACGTGAAGCTGCATGTT TCTTTTGGGACACTTATTGTTAAGTTGCTGTTTCTCTATTCTGTAATACATTTCCCACTTTATCATACATCATGTACAAT TGTTAATGCTTCCATGTCCCATTGTTTTTATGATGTTACACTTTTTTTGGAAGAGTAGCATGAACATGATACTAGTGTTA GTATGACGAGTTCATAGCCTATTCAATAAGAGAGGAGGGCTGTTGGAGCCTCCATATTCAAGAGGGTTTTTTTGGACATG TGCCTAGTGTCCTTTGTCTTTTCTTGATGCTTTTCATGGCTTTCCTCAGCCAATTTTCTAGCCTCTCCACGTC
CDS sequence (LotjaGi1g1v0417900.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGCCCGCAGTTCACTCTTTCTCTAAACCGGCTGCTGAACCGCGAACCGGAATCGAAGAGGCCGCGAAACGCAAGAAGGA GAAGGAGAACCTGCAGAAAAATCCGCAACAACAACAACAACAACAACGTCTGAGAAAGCAGGTAGTGCAGGAAATCTCTG ACTCCATTGTTGTACGATGTAACAACGTGTCTTTGGACAGCACGTGCTCCTCGGATTCATGTTCCAGTAAGTCCATGTCG GTCAAAAAAGTCAACTCAACAACAAAGACCTCAAATGCAAGTGCAACTAGTAGGAGGAGGAACGCGAGGTGCACTGGGTT TAAGCCGGCGAGGGTTGTGCCGGATGCAGCTGCAGTGTCTCCGCCTTCCAACGCCTCAGCACCGCCCAAGAAGTGTGATT GGATCACACCTAATTCCGACCCACTGTATAGTGCTTTCCATGATGAAGAATGGGGTGTTCCAGTCGTCCATGATGATAGA AAGCTATTTGAGCTTCTAGTCTTCTCACAAGCATTAGCAGAACACACTTGGCCATCAATTCTTAGCCACAGAGACATGTT CAGGCATCTTTTTGAAAACTTTGCTCCATCGTCAATTGCTCAGTTTACTGAGAAGGAGTTGCTAACACCGAAAATAAACG GCAAGCCATTGTTATCAGAACCAAAGCTCCGCGCCATTGTCGAAAATGCTAAACAATTACTTAAGGTCCAGCAGGAGTTT GGTTCATTCAGCAATTATTGCTGGAGATTTGTTAGCCACAAACCAATAAGAAATGAATTTCGGTATGGACGACAAGTACC TGTGAAGACTCCAAAAGCAGAACTCATTAGCAAGGACATGATGCGGAGGGGTTTCCAATGTGTGGGACCAACGGTAGTTT ATTCATTCATGCAAGTAGCAGGACTCGTAAATGATCACCTAGTAACATGTTTCAGGTTCCATGAATGCAGCAATGTGACT CTCAAAAACGAATTCAAAACAGAGGTTAAGGAGAAAAAGGTAGAAAATGAAACTGTGAATTTGACAAAGATTCAGTGA
Protein sequence (LotjaGi1g1v0417900.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MPAVHSFSKPAAEPRTGIEEAAKRKKEKENLQKNPQQQQQQQRLRKQVVQEISDSIVVRCNNVSLDSTCSSDSCSSKSMS VKKVNSTTKTSNASATSRRRNARCTGFKPARVVPDAAAVSPPSNASAPPKKCDWITPNSDPLYSAFHDEEWGVPVVHDDR KLFELLVFSQALAEHTWPSILSHRDMFRHLFENFAPSSIAQFTEKELLTPKINGKPLLSEPKLRAIVENAKQLLKVQQEF GSFSNYCWRFVSHKPIRNEFRYGRQVPVKTPKAELISKDMMRRGFQCVGPTVVYSFMQVAGLVNDHLVTCFRFHECSNVT LKNEFKTEVKEKKVENETVNLTKIQ
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| MobiDBLite | 1 | 47 | 47 | - | – | |
| PANTHER | 3 | 337 | 335 | 2.6E-141 | – | |
| PANTHER | 3 | 337 | 335 | 2.6E-141 | – | |
| MobiDBLite | 16 | 32 | 17 | - | – | |
| MobiDBLite | 33 | 47 | 15 | - | – | |
| MobiDBLite | 66 | 102 | 37 | - | – | |
| MobiDBLite | 66 | 101 | 36 | - | – | |
| Gene3D | 130 | 317 | 188 | 9.5E-65 | – | |
| SUPERFAMILY | 130 | 316 | 187 | 1.88E-60 | ||
| Pfam | 138 | 312 | 175 | 4.3E-59 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | ||
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
| Biological process | Base-excision repair | In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. | ||
| Molecular function | DNA-3-methyladenine glycosylase activity | Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site. |
Expression pattern of LotjaGi1g1v0417900.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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