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| Field | Value |
|---|---|
| Gene ID | LotjaGi2g1v0338700 |
| Transcript ID | LotjaGi2g1v0338700.2 |
| Related isoforms 2 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Guanine nucleotide-binding protein subunit alpha-like protein; TAIR: AT1G31930.1 extra-large GTP-binding protein 3; Swiss-Prot: sp|Q9C516|XLG3_ARATH Extra-large guanine nucleotide-binding protein 3; TrEMBL-Plants: tr|I1J4M8|I1J4M8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0338700 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr2:81553900..81560339) extracted from Lotus japonicus Gifu genome v1.2.
CACAACACCAAGATTATTATTACTAGCATTTAGCAATGTGGGGCTCACTGGGCCCAGAACCCTCTCACTCTCAACAGCTC TCTCTTCTTCTTCATTGATTTTCTTTCACCTTCTTCTACTTACTTTCTGAACCAACTCAACCTTCACTCACATCTCACTT TCCTTCATCAATGTTGGTCGTGGGTTTCGGGAAACCTTTGTCTTTTCCAGATTTTCAAGATCGGATTCGCTTTCACTCTG TCCCTTTTCTTAGGTACACCCCTCTTTCTCTTTCACTCCCTCAAAAGTTCAAAGTCATCTTTTTTCCTCATCTTTTTCAA AAAAAAAGAAAGACCCTTTTTTCTTCTTCTTCTTTTGTTTATTCTTTTCTTAGCTAGCTGAAAATTGTAACATTTGACTC TCAGTTTTTCAACACCCCCATAAGAGAAAAACCAACACTTATGACCTTCAAAGGTTGGTAATATTGAATTTTCTTTTTCA CTTCTTCATGGTTTTTCTTATTTGTCTGAAGTCATGCTTGGATACCCTGATTTGAATTTTGTTTATTCTCATTTGATTTT CTTAAAGCTGACTTTTTATTGGTGGGGGTTCATTTCTTATAAAAATGAAGTTGTTCAATTATGAAGGCTTTCAATTCAAC GTTTGATTGCGGCTGCTTCATGACTGTGACTGGGTCTGGTTCTATTTTTGTATACAAGACAAAACCTAAAAAACCTCTTT CTGTTGCAACAGAATTTTCCACCAAAGATTTTTCTGTTCTTTCTATTTATTTAGCTCATTTATCTCTATGCTTAGATGTG TTGATTTCTATCTAGTTACATAGGTTTTGGGATGTCATGTTTCAGAGAGAACACAGGTCTTGTAGATTTTGCTGATGCTG AATAGCTTAAACTTGGAAGCATAAGAGGGTGTTAGTGATTGCAAAATATGGATCCAAATAGGGGAGATAGCTGGAGGGAA TTGGTCAAGAAGATGCTTCCTCCTGGTGCTTCTGTTCCTGATGATGCTTCTGATCTTGATTACTCTATAGCTCTTGAATA TGAAGGTCCACCGGTTTCGTATGAAGTGCCAAGAGTTGAGCCCTTCGATGTGAACTCAAGAGAAATTCCCACTGCTGAAC CACTGTCTGGATCACAAAGATCAAGTACTCATGTGATTGAACCTATCCCTCTGCCGGTGTCTCGTATTGCAGGTGTGACG GGGTCTCCTAATCATAGCCCGAGGGTGTCGGGAAGTTCAGAATCTGTGGTTTCGGTGTTGCAGAACCCGGATCTTTCTTC TGCGTCGCCTTCTGCTTCGCCTGCTTCAGTTCATAATCCTGCTAACAATCCTCCTATGCCGGCGGCTAATGAAGCAAAGA GGGCGCCTGTTGTCACTTTTAATACTGTTGATAGATCTCAGACGAAAGAGGTGGAGGTTGTGAAGCCGGTTTATCCGGAA TACGTCGGGGTTTTGAAAGAAAGGAAGAAGAAGAAAATAAGAGTTTGCTATAGGTGTGGGAAAGGGAAGTGGGAAACTAA GGAGTCTTGCATAGTTTGTGATGCCAAGTATTGCAGTAACTGTGTGCTAAGGGCGATGGGATCGATGCCAGAAGGGCGCA AGTGCGTAACTTGTATTGGTCAGCCAATTGATGAATCCAAGCGTCTGAAATTGGGTAAATATTCGAGGGTGTTGTCCCGG CTGTTAAGTCCTCTAGAAGTCAAGCAAATTATGAAGGCAGAGAAAGAGTGTTCTGCTAATCAGCTTAGGCCGGAGCAGTT GATTGTGAATGGATTGCCCCTGAAGCCAGATGAGATGGCAGACCTACTTGGGTGCCCCTTACCTCCACGTAAGCTGAAGC CCGGTAGATATTGGTATGACAAAGAATCTGGTCTTTGGGGAAAGGTGATAATTTGTGCTTTATTGTTGACAATATTAATT CTGCTTCAACTTTCCCTTGTAAATAATATTATTTTTTAATTGTGATTACATTGAGTATATCAAATTCATAAGATTAACTT ATCAAAGTGTTAAATTTCATTTTTCTTGGCATATCAAAAGTATTATGTCAAATTCATGTGGTTAACTTGTCAAAATGCTA TGTTTCCATTTCTAATCTCAGAGCAGGTTTTTATTTCTGTCCTTGTTCATTTGATAGGAAGGGGAAAAACCTGACAGACT CATAAGCTCGAACTTGAATTTCACGGGGAAACTCTGCTTTGACGCTAGTAATGGAAACACTGAGGTTTACATCAATGGTC GAGAGATTACTAAACTTGAATTGAGGGTACTCAAGGTAAGCTTTTATCTTTGTTTAAATTTAAACAAAATTTATATTTAC TATATTTAGTTGCAACTTTGATTCAGCTGTCAGACTAAAGGAGTGCTCAGTAAGAGTGAAAATGGAAGTAGTGGGTGCGG GTGTGCCGCCACAGCCACCAGATTTTTCGAGATATGAACATCTGACTGCAGCTATTACCCAAAGCTCGGATGTTTTGAAA CGATAAGACATTTTTGACATTATAACGGAGAAAGGATAATAACAAAAAACCTCTCACCTAACAGACAACCTTATTTCTAA TCTTTGGATGGTCATTATCATCATCATGGCATTATAGTATTATTAAATGCAATGGAATAATCCTGTCGTTTGAATTTTCA GCTGGCAAACGTGCAGTGTCCGCGTGATACACACTTTTGGGTTTATGATGATGGTCGTTATGAGGAGGAAGGTCAAAATA ATATCAGAGGAAACATTTGGGGGAAGGTACTAACCAACATATTTGTTTGTGGGAGCATCTTTATATCATATGAGAGTGTA GAATATTAATGAAAGAGTTGTTAATTTTTTCTTGGATAGGCATCAACAAGATTTGTTTGTGCCCTGTTCTCTCTGCCCTT TCCCCACGGACAGCCTCATGGGACAAGAGATGAGATTAGTAATTATACCACAGTTCCTAATTATCTAGAAAAGAAAAAGA TTCAGAAGCTTCTTCTTCTTGGAATTCAAGGGTCTGGAACTAGCACAATATTTAAGCAGGTACAGTTTTTATTTCAAATG TTTACACCTATGTTCATGATAGTTACTTCTGATAAACACTTCAATTGTTTTGATATATATGAGAACTTAGTAGTTCACTG ATGCATTTTTTTTCTTCTTATTATTTTCTTTATTCCAAACACCCCCCTTTTTTTCTTTCGATTCTTTTACTAAGCTGTGT ATGGTTGGGAGTTGATATGAGATTGGCACCAAGTGAAATTTTTTGTAGTTTGGTCATTTACACCAATGGTATTAAGATAA AAGCATTTTTTGGAACCTAGTGTGTTTAGTATTGATTCTATTCTGTGGCACTCTTGTAATTGCTGAGCAGGCCAAGTTTT TGTATGGGGACAAGTTCACTACTGAAGAGCTGCAGGATGTCAAACTGATGATCCAGAGTAACATGTACAAGTATCTTAGC ATTTTGCTCGATGGAAGAGAGCGCTTTGAAGAGGAGGCTGTTTCTAGAATGAATGAACAAGGTTCCCCTGGCCAAACTAC AGAACCAGGTAATATTTCATGTCATGGTAATTTTCTTCTTGGAAAAAGTTTTGTTCACCACTCAATTCCACCCACACCTA GTGAGAGAGTGGAATAGAAGAGAGAAATATGAGATATGATAGGTGCTGTGATAGGAAAAGAAGAGACATATAGGAAGAGA AAAGTGAGTGGAAATGTGATGGAGGAGAAAGTTAGGTGGGAATGTGTCAAAACCTTTCTTCAAGTTTCCACTTCATGTGT CACTGTTTAGCTGACGAGAGACCATGTATGATGGAACACTACTTCAACTTTATGCCTCAATTATCATCAACCACATACAC TTACTTTCGATTGTTATAAATAACAACACTATTGAAAACTAAAACATCAGATTCATTCCTAGTTTATCTTAAAAATGGCT AATATACTGCAAATGTGTTGTTTATCAATATAGATTTGGTCTGTGTGAATGCTAATCCTATGGGCAACTTTTATTTGATC TGTAATGGATCAGAATGCTTCCAGTGTATCACCAGATTTCAATATTTATTCAGGTAGCAATGGTGAAGCAAGTAATACTA GTGAATGCATCTATTCCCTCAACCCAAGGCTAAAGCATTTCTCTGACTGGTTGTTGGACATTATAGCTACTGGGGATTTA GATGCATTCTTCCCTGCAGCCACACGTGAATATGCACCGTTAGTTGAAGAAGTGTGGAAGGATCCAGCAATACAAGAAAC CTTCAAAAGAAAAGATGAGCTTCACTTTCTTCCAGATGTTGCAGAGTACTTCTTAAGCCGGGTAATTGCTTATCATTTCA TCCTTGAAACTGTGTCCTCCTGTTCAGTTAAAGTTGGCAGGCATCTGACGTTTACTGAATCTTAACCTCACAATCCGTTT TTATTCCTGCTGATTTTTTCGTAAAATTTGTATGTTCTTCTGATTTAAGAGCTTAGATGCTACTTTCTTGAGTTAAATAT TCCTTGCATGCTTTGTCTGATTAGCCTAATATTCTACTGCTTTGCCAATTAGTTTCATCACTTGTATGCCTCAGTGCAAT ATCTATCTTCTCTGCTATTCATTTTGTTAGGATTTGTTTGAAATGAAAATAGAAGATAGAACACTTGTGTAACTTTTCTG GTTATTAACATTTACAAATGCTGTGAGAAGTAGAAACGGTTATTATTTTGCTAGCATGGGTTGCCTTTTCAGCTTTAGGA AAATCAATGGTATTGACATGTATAGCTTGGTAACGAGCTCTTGTTTCTTCCAGGCTGTTGAGATATCTAGCAATGAATAC GAACCTTCTGAAAGGGACATACTTTATGCAGAAGGGGTTACACAGGGAAATGGCTTGGCTTTCATGGAATACTCCCTAGA TGACCGTTTGCCAAGGTCGGAGACTTACACAGATAACCTGGATGGTCAGCTTCCACCTCTGACCAAGTAAGCTATCTTTA TTCCTTTCTGAATTTCAGAAGCCTCTTTTTTCTGAGGGAAAGTTTCCTGCATAGTTAAACTTTTGCTCTCTTTCTCTTTT GTATCTCTCTTTTTTTCTTTAGAGGGGGGCAATAGGAGTTAAGTGCGTTTGGCTCCACATTTGGGAGCTTTAGAATCAAT TCTGTGACCAAAAATCACTTTTAGGTGGTTATATAGGTGTTTGGAAATCTACTTCGAGAATTGATTTTAGTCCCAAAATC AACTATGCGGAGAAGCTAGAGTGAGCAGCTTCTGCGGTGAACATAATCAATTGTGAGAGTATTTGAGGGATATCTTGAAG TACATTGCAAATTTTGTTTATTTTTAAAAACGAAGATGAAGGGAGTCTTGGCGCAACGGTAAAAGTTTTTGCCATGTGTC TCATGTCACAGGTTCATGTCCTGGAAACATTCTCTACCATTCCCTGAACCTGCGCATAGTATGAACTTTCGTGGATGGAG CTGCCATTTTTACAAAAACGAAGATGACTAATAACTTCTCTTTGATGTCTCAGGTACCAGCTCATAAGGGTGAACGCCAA GGGCATGAGTGAGGGTTGCAAGTGGGTTGAAATGTTTGAAGATGTCCGAGCAGTGGTCTTTTGCGTTTCCCTCAGCGACT TCGACCAGTTGTGGCTTGCCCCAGACAGCAGCGGCAGCGGCACACTTCTTCAAAACAAGATGATACAAAGCAAGGAGCTT TTCGAGACCATGGTGAGGCACCCTTGCTTCAAAGACACCCCATTTGTCCTGGTCCTGAACAAATACGACATGTTTGAGGA AAAAATGAGTAGGGTGTCCTTAAATGCTTGTGAATGGTTCAGCGATTTTTGTCCCGTGCTCGCACACCAAAACAACCAGT CACTGGCACATCAGGCTTACTTCTACGTCGCAATGAAATTCAAGGACCTCTATGCATCCCTCACGGGAAGGAAACTTTTT GTGGCACAAGCAAGAGCGAGGGACCGAGTAACTGTTGATGAGGCATTTAAGTACATAAAAGAGGTTCTCAAGTGGGATGA GGAAAAGGACGAGAATTACTATGGTCCACCTGAGGATTCATTTTACAGCACAGACATAAGCTCCTCTCCCTATATCAGAC AAGAGTAAACAATGTCCATCAAAATTTATTATTGAGTTATGGATAAGGGTGGAATATGTAACATGCTGGCCAGGTTCTGG TGTCTGATATTTATGTAGTGAAATTGAAATCTGTAATGGAAAAAGTTATTTATTCTGGTAGAGTTCGTTTGAAAAGATGA ATATTTGTCCTGTTTCTGCATGACTGCATGTATGATGTATTGCATGTGGAGGCGTTGTTCATTGGTCCTGGAGCTTTTAC AGGTGTTTGGTTGGAAGGGAGGGTGTGTTTAAAAACTCTAGAGGCATGGTTCAATTTTTTGGAAGGGAAAAGGGAATAGG GTAGGGTTCACGGGTTGGGTTGGTATGTATTTGAGGTATA
CDS sequence (LotjaGi2g1v0338700.2) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGGATCCAAATAGGGGAGATAGCTGGAGGGAATTGGTCAAGAAGATGCTTCCTCCTGGTGCTTCTGTTCCTGATGATGC TTCTGATCTTGATTACTCTATAGCTCTTGAATATGAAGGTCCACCGGTTTCGTATGAAGTGCCAAGAGTTGAGCCCTTCG ATGTGAACTCAAGAGAAATTCCCACTGCTGAACCACTGTCTGGATCACAAAGATCAAGTACTCATGTGATTGAACCTATC CCTCTGCCGGTGTCTCGTATTGCAGGTGTGACGGGGTCTCCTAATCATAGCCCGAGGGTGTCGGGAAGTTCAGAATCTGT GGTTTCGGTGTTGCAGAACCCGGATCTTTCTTCTGCGTCGCCTTCTGCTTCGCCTGCTTCAGTTCATAATCCTGCTAACA ATCCTCCTATGCCGGCGGCTAATGAAGCAAAGAGGGCGCCTGTTGTCACTTTTAATACTGTTGATAGATCTCAGACGAAA GAGGTGGAGGTTGTGAAGCCGGTTTATCCGGAATACGTCGGGGTTTTGAAAGAAAGGAAGAAGAAGAAAATAAGAGTTTG CTATAGGTGTGGGAAAGGGAAGTGGGAAACTAAGGAGTCTTGCATAGTTTGTGATGCCAAGTATTGCAGTAACTGTGTGC TAAGGGCGATGGGATCGATGCCAGAAGGGCGCAAGTGCGTAACTTGTATTGGTCAGCCAATTGATGAATCCAAGCGTCTG AAATTGGGTAAATATTCGAGGGTGTTGTCCCGGCTGTTAAGTCCTCTAGAAGTCAAGCAAATTATGAAGGCAGAGAAAGA GTGTTCTGCTAATCAGCTTAGGCCGGAGCAGTTGATTGTGAATGGATTGCCCCTGAAGCCAGATGAGATGGCAGACCTAC TTGGGTGCCCCTTACCTCCACGTAAGCTGAAGCCCGGTAGATATTGGTATGACAAAGAATCTGGTCTTTGGGGAAAGGAA GGGGAAAAACCTGACAGACTCATAAGCTCGAACTTGAATTTCACGGGGAAACTCTGCTTTGACGCTAGTAATGGAAACAC TGAGGTTTACATCAATGGTCGAGAGATTACTAAACTTGAATTGAGGGTACTCAAGCTGGCAAACGTGCAGTGTCCGCGTG ATACACACTTTTGGGTTTATGATGATGGTCGTTATGAGGAGGAAGGTCAAAATAATATCAGAGGAAACATTTGGGGGAAG GCATCAACAAGATTTGTTTGTGCCCTGTTCTCTCTGCCCTTTCCCCACGGACAGCCTCATGGGACAAGAGATGAGATTAG TAATTATACCACAGTTCCTAATTATCTAGAAAAGAAAAAGATTCAGAAGCTTCTTCTTCTTGGAATTCAAGGGTCTGGAA CTAGCACAATATTTAAGCAGGCCAAGTTTTTGTATGGGGACAAGTTCACTACTGAAGAGCTGCAGGATGTCAAACTGATG ATCCAGAGTAACATGTACAAGTATCTTAGCATTTTGCTCGATGGAAGAGAGCGCTTTGAAGAGGAGGCTGTTTCTAGAAT GAATGAACAAGGTTCCCCTGGCCAAACTACAGAACCAGGTAGCAATGGTGAAGCAAGTAATACTAGTGAATGCATCTATT CCCTCAACCCAAGGCTAAAGCATTTCTCTGACTGGTTGTTGGACATTATAGCTACTGGGGATTTAGATGCATTCTTCCCT GCAGCCACACGTGAATATGCACCGTTAGTTGAAGAAGTGTGGAAGGATCCAGCAATACAAGAAACCTTCAAAAGAAAAGA TGAGCTTCACTTTCTTCCAGATGTTGCAGAGTACTTCTTAAGCCGGGCTGTTGAGATATCTAGCAATGAATACGAACCTT CTGAAAGGGACATACTTTATGCAGAAGGGGTTACACAGGGAAATGGCTTGGCTTTCATGGAATACTCCCTAGATGACCGT TTGCCAAGGTCGGAGACTTACACAGATAACCTGGATGGTCAGCTTCCACCTCTGACCAAGTACCAGCTCATAAGGGTGAA CGCCAAGGGCATGAGTGAGGGTTGCAAGTGGGTTGAAATGTTTGAAGATGTCCGAGCAGTGGTCTTTTGCGTTTCCCTCA GCGACTTCGACCAGTTGTGGCTTGCCCCAGACAGCAGCGGCAGCGGCACACTTCTTCAAAACAAGATGATACAAAGCAAG GAGCTTTTCGAGACCATGGTGAGGCACCCTTGCTTCAAAGACACCCCATTTGTCCTGGTCCTGAACAAATACGACATGTT TGAGGAAAAAATGAGTAGGGTGTCCTTAAATGCTTGTGAATGGTTCAGCGATTTTTGTCCCGTGCTCGCACACCAAAACA ACCAGTCACTGGCACATCAGGCTTACTTCTACGTCGCAATGAAATTCAAGGACCTCTATGCATCCCTCACGGGAAGGAAA CTTTTTGTGGCACAAGCAAGAGCGAGGGACCGAGTAACTGTTGATGAGGCATTTAAGTACATAAAAGAGGTTCTCAAGTG GGATGAGGAAAAGGACGAGAATTACTATGGTCCACCTGAGGATTCATTTTACAGCACAGACATAAGCTCCTCTCCCTATA TCAGACAAGAGTAA
Protein sequence (LotjaGi2g1v0338700.2) extracted from Lotus japonicus Gifu v1.2 Proteins.
MDPNRGDSWRELVKKMLPPGASVPDDASDLDYSIALEYEGPPVSYEVPRVEPFDVNSREIPTAEPLSGSQRSSTHVIEPI PLPVSRIAGVTGSPNHSPRVSGSSESVVSVLQNPDLSSASPSASPASVHNPANNPPMPAANEAKRAPVVTFNTVDRSQTK EVEVVKPVYPEYVGVLKERKKKKIRVCYRCGKGKWETKESCIVCDAKYCSNCVLRAMGSMPEGRKCVTCIGQPIDESKRL KLGKYSRVLSRLLSPLEVKQIMKAEKECSANQLRPEQLIVNGLPLKPDEMADLLGCPLPPRKLKPGRYWYDKESGLWGKE GEKPDRLISSNLNFTGKLCFDASNGNTEVYINGREITKLELRVLKLANVQCPRDTHFWVYDDGRYEEEGQNNIRGNIWGK ASTRFVCALFSLPFPHGQPHGTRDEISNYTTVPNYLEKKKIQKLLLLGIQGSGTSTIFKQAKFLYGDKFTTEELQDVKLM IQSNMYKYLSILLDGRERFEEEAVSRMNEQGSPGQTTEPGSNGEASNTSECIYSLNPRLKHFSDWLLDIIATGDLDAFFP AATREYAPLVEEVWKDPAIQETFKRKDELHFLPDVAEYFLSRAVEISSNEYEPSERDILYAEGVTQGNGLAFMEYSLDDR LPRSETYTDNLDGQLPPLTKYQLIRVNAKGMSEGCKWVEMFEDVRAVVFCVSLSDFDQLWLAPDSSGSGTLLQNKMIQSK ELFETMVRHPCFKDTPFVLVLNKYDMFEEKMSRVSLNACEWFSDFCPVLAHQNNQSLAHQAYFYVAMKFKDLYASLTGRK LFVAQARARDRVTVDEAFKYIKEVLKWDEEKDENYYGPPEDSFYSTDISSSPYIRQE
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | 10 | 846 | 837 | 0.0 | – | |
| PANTHER | 10 | 846 | 837 | 0.0 | ||
| MobiDBLite | 87 | 143 | 57 | - | – | |
| MobiDBLite | 90 | 130 | 41 | - | – | |
| SUPERFAMILY | 163 | 230 | 68 | 1.34E-5 | ||
| SMART | 430 | 814 | 385 | 2.0E-15 | ||
| Pfam | 437 | 824 | 388 | 2.0E-67 | ||
| SUPERFAMILY | 438 | 832 | 395 | 2.49E-23 | ||
| ProSiteProfiles | 440 | 836 | 397 | 58.258 | – | |
| Gene3D | 443 | 811 | 369 | 2.2E-76 | – | |
| PRINTS | 443 | 458 | 16 | 2.5E-10 | ||
| CDD | 448 | 828 | 381 | 4.39161E-80 | ||
| SUPERFAMILY | 469 | 621 | 153 | 2.49E-20 | ||
| Gene3D | 470 | 624 | 155 | 2.2E-76 | ||
| MobiDBLite | 502 | 528 | 27 | - | – | |
| MobiDBLite | 508 | 528 | 21 | - | – | |
| PRINTS | 611 | 633 | 23 | 2.5E-10 | ||
| PRINTS | 684 | 712 | 29 | 2.5E-10 | ||
| PRINTS | 737 | 746 | 10 | 2.5E-10 | ||
| MobiDBLite | 832 | 857 | 26 | - | – | |
| MobiDBLite | 843 | 857 | 15 | - | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + phosphate. | ||
| Biological process | Signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. | ||
| Biological process | G protein-coupled receptor signaling pathway | A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576). | ||
| Molecular function | Guanyl nucleotide binding | Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate. | ||
| Molecular function | G-protein beta/gamma-subunit complex binding | Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits. |
Expression pattern of LotjaGi2g1v0338700.2, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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