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| Field | Value |
|---|---|
| Gene ID | LotjaGi5g1v0045000 |
| Transcript ID | LotjaGi5g1v0045000.5 |
| Related isoforms 7 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Guanine nucleotide-binding protein subunit alpha-like protein; TAIR: AT2G26300.1 G protein alpha subunit 1; Swiss-Prot: sp|P49082|GPA1_LOTJA Guanine nucleotide-binding protein alpha-1 subunit; TrEMBL-Plants: tr|I1MX88|I1MX88_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0045000 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr5:7596990..7605045) extracted from Lotus japonicus Gifu genome v1.2.
ATGCTGTCTTTTGTTACAGAAAATATGGGATTACTATGTAGCAAAAATCGCCGTTATAATGATGCTGACACTGAAGAAAA TGCACAGGTAAGTTGCATAGTTTTTTAGTTCTTAATAATCTGAAAGTGTCCATGGCCTTTAATTTGATAAATGTGACATG CATTTGCAGACTGCAGAAATTGAAAGAAGAATAGAGTTAGAAACGAAGGCTGAAAAACATATTCAGAAACTTCTTCTACT AGGTACATTTTACTTGGGCAATTTTATTATTTTATGTCAGTTGGATTGTATATGTTTCACTTGTACATTTTCAAGTTAAA ATTTGTCTATTTTAGTGGTTTCTAGGAGTATTTGGAATCTAGTGTTGTGTAAGTAGTAGTGATGCTCCCCAGATTTTGAA GGAACGGCTAGTATCATTTATATGGTTTCTGCTGGTAATTGATGCGTTTCCTAAAACTGGCATTTCTGCATTATAAGATC TTCTACTTTAAAAAGGAGTTGCTTAACTTCTGATTGAGGGGTATTTGATTCATAACTCAATATGTATTTTAGATATAAAA CCATTTGCTGGCCTTCACCTAATAGGTTAAGCTTTTAGAATAGTTCAAACTTAATTTCTTTCCAATTCCAATGTAAACAT AATGGCAAAACACATTCTCCAGTGTCAAATTGTGATAGGAGCTAGAGCTCTCTGTTGAAGTTAAATTATGTTCACTTTTA GGCAACTACAATACAAACATACCTTAATGTGTGTTTGGATACCAGCTGAGTGCAATGTGAAGTACTTTCATCCCAAACCA TAAGAGTTTGGTTCACTTTTTACCTTGAAGTGAGCGCTAATGGCTGTTTGGATATTCAAACATAGGAGTTTGGTCGTTGC GCTCATTTTTCTAAAGACAATTCGTGGCAGAAAGTTTAGTCTTGATAGTACAAGAAACTTTTTGTTTACTCATGCCTTTA GGATTTAGAATGATATGTGTATCAGGTTTTCCTTGTATATCTTGGATTATTGCTCCAATTCTTCTGTTAAGTGATCTATC GTGGTCCTCAGAAACAATGCCATACTTATTTTGATTGAATCCTATGTGTGATAATCTGTCGATTCGTTTCTTGCTTGCTT TTGTTTTTTGTCAAGAATCAATTATCCCACAAGCTTAAGCTGTTGGGTAAAAGACGCATGAATGGTTTTATTTTTTATAT TTCTAACACGCCCCCTCACGCAAGAGCCCGCCTGGGCTTGAAGCGTAAACAAATGCACAAGCCCACTTCCCATGTGCTGA AATTCAACTTTTTTACTTTTATTAGAACAATTGGGGTGGCAAGGATTGAACTCTAGACCACTTGGTCATAGAGGCTCTGA TACCATGTCAAGAACCAATTTTCCCAAAAGCTTAAGCTGTTGGGTAAATGACACATGGATGGTTTATATTATATTTCTAA CATTTTTTTATTTCTAACTTATTTAAATGTGCCATGGCCCTGTTGTTCAGGAGCCGGAGAGTCAGGGAAGTCTACAATCT TTAAACAGGCAAGAAAATGCACTGTTCTCTATATTTTAGCGTTGTAGATACTTTCTAGATTGGTGATATTTATTTAACTG TCTATATATGCAGATAAAACTTTTGTTTCAAACTGGCTTTGACGAGGCAGAGCTAAAAAGCTACCAACCAGTCATACATG CTAATGTATATCAGACAATAAAAGTACGCAATACTTGAAAGGGTGTGTTGATTATTTTTCTCTTAAAAATACAGAGTTTG CAGTGTCCACTGATAATAATTGAAAAGGTTTTCTATGAATTGTGTCTCAATGGATCTAGCTAAGTAAACTGTCTTGCTTA AGATGTGTCTGTTATGTCTCAACAGTTACTGCATGACGGAGCAAAGGAGTTGGCCCAGAATGATGTTGATTTTTCAAAGT ATGTTATATCCGATGAAAACAAGGTAGGTCACTGTTACCTTCTCTGTTATCCCCTATGGTTTAGACAATAATTTTATATT GTATCTTGTAAAACAAAATTTATTATAAATAAATTTAGAGTAAACACTTGTACATAGGCTTCTTTTTTTCTTTTTTCTGT TTTGTGGGAATCTGTTAGTTTGTTGAACTTAGGTGGCAAAGAATTTTCTTCTAAATTCATATGAAGCTTTCTTAACTTTT TTGGCAGGAAATTGGGGAAAAGTTATCAGAAATTGGGGGCAGGCTGGATTACCCCTGTCTCACCAAGGAACTAGCACTGG AAATAGAGAATTTATGGAAGGATGCTGCAATTCAGGTGGCTATATGACATAGTTCATTGCTTTTATTACTGTAATCCATC TATGTATTTATTTTCCGCTTCAGTTATTTAGTATTATGAGCACATGTTTTACTTTCTGCAGGAAACATATGCCCGCGGTA ATGAGCTCCAAGTTCCAGATTGTACCCACTATTTCATGGAAAATCTGCACAGACTGTCCGATGCAAATTATGTTCCAACA AAGGTATCCAAAATCTATCATACTTTTGTTGATTACTTAAATTTTATTTTTATCTATCTACTTGGTAAAATTAGAGACCA TATCATAATAGAAGATCAACAAGGGATAGTTGAGATGAGGGATAGTTCTATAGTTAGAGTTAGAGGGAGACCATGAAAGA AAACTATAGGTCAACTATGAAAAAGAATTTATATTTAAATGGTCTATCATTTGACATGATTTATGATAAGAGACATTATT GCATTGTTTAATTTTCATCTATTTAGCTGACCCCACCTAATTGGAAAAAAGGCATTTGTTGTTATTGTTATTGGTATGTT GAGAATCTGATTTATTTCTTCTTGGTGGGTGTGGTATTTTTTATTTTATGGATGTTTAGAATTTGAGGATCCAAATCTTT TTCTTCTCTTCTCTTTTGGCCTTTTGTTGCTGTAGTATATAATATGCATGGGTTACAACTTACAACCCATGAGATTTTTT TTTTAATTTTATAAAAAAAGTCAGTTAAAATGGTCTGAAAAAGTATATTGTTGCATGTTTTGAAAAAAAGGAAATTCTAC CGTAGCATTCTGTCTTAAAAATCATAAGTAATTTGTGGTTTGTAAATCTGTCTTGAATTGCCGTATTTTGCTTCTTTTTT CCTTGCATCAAATTATTTTCTATTTTGCCTTTGGTTGGTATTTTATTGTTAGAATATTTGGAAAAATCTATAATATATGG ATTGTATATTCGAGTAATTTAGATCGTATTTCTACTGTTTGTATACAGCAAAATTGACTGTTTTAGTAGTTTGTTGGGTT ATCTGAGAAGACCTTTTTTGGTCGTCTCTGTTAGCATTGTCGCTAGGGCACAGCCCACTCACTATCACAGCAACATTTAA GAAGTTTTCTATCAGGCTCACGAAGGCCACACATCGCATTGCTGACCTTGTTTAACATAACCATCAGTCTAGTCATATTT GTCAGCACCTCTTCTATTCTGCACTAATTTGGCTGTTTTTGCGGAAGAATTTCATGGCTTTGCTTTCCCCCCTGTTTTGG CTCGCTTGTGCCTCTGTTTGTATCAGTTGTGGTTTGACCCTGATTCTGCTTTAGATCTTTATGTTGGCGCTTGTTCCACT GTCATCTCCTCCTTCTGGCTGTCTCGGTAGCCTTTAGGTCCCATCAACCTCTGTCCACATGTATGGTCCCCTCAATCCAA GAAGCACCGTAACCGTGATAGTCCCAGTGTAACAATCCCCAGAGAAACAGCCTGCCTTTCCAATAGTTACCAAAAATAAC TTATTATCATCAAGATTTTTTTCTTATAGTATCTTAAGATATTTTTCTAAAGGTACACTTGTGACAAACTTAAAGCTAAG TAACCTTTGACATGAGAAGGCTTTTTAGAACATAAAAAATATGTATTATTATTATTACCATATGATCTTGATCACATCTT AGAGTAATTTAGGGTAATTTAGATTATTCCTTAAGATTGGTTCCTATATTTCCGTATATCCTTATTTAATTAAGATTTGG AGTTCATTATTAAATAATTAAGGATTAGTTTTTGGCTTTTGTATTACACCCAACATATCATTCACATCATATCAATACAA TTTTATTATTCTCAACATTACTTTTCCTCTTTCTATACTTAAAGACTAAATACACGGCATGTCTTGGATGACGTTAAGCG AAATTTTAATTTCTTTTGCAGTCATAGACCATTAAATTTTACATGGCTGTAAGGTCATGAACTATAATAACTTCTCATTC TATTATACACCTGCAGGATGATGTTTTGTATGCAAGAGTGCGTACCACTGGTGTTGTAGAGATCCAGTTCAGGTAAACAT TTTGATTGACTTGATCTGTCATGCTAAATCATACAGAGAGATACTTATTACTGCCCCCATTTTATTCCCTTCCTGATATG CTTAGTATGTGGAGAATAATGGCCCTTATTACATAGATTTGGGCATTTCTTCTCTTTCTTTTCTGTCATTATGTTTATCT TTTAGTTTTGGTTACCAGCAGGAAAAATAATCCTCCTGCATCTTGTTGTGTTTCACCTTGGAGGAAAGGGCAATGAGGTG GACTAACACCTAGAGTATTAGATGAGTGCAGCCAGTCCAACGTAGTTAGCCTATCCTAGAAGGAAAATGCTATTAGTTAG GTGAAGCCATGATAGAAACTGAGATTTACTCAATAAATAATAGCAGGATTTCGAGAACGAACTCTGTTTAGATGGAAAGT AGTAGGCGAAAATTCAAAGATGTCAGAGAAACAAGAATGCTACTCTGCCCCTAGGCCTAAACCTCCCACAATTCCCCTCC AGTTTTTATGCCTCTTCTGGAATTTGTTAGGCTTCTCATTCACTGACTCCACCTCAATTCCCATCTTGCCCTTTATGCCT CTGATATTTTTTATCTTATTGTTTATGGGTTTACCACTCATGGTAAGGTAAAGCATAGTAAAGTTGAACATAAGGATTCA TAAATTAGCTTAAACTATCTTGATTTTTAGGTTTTAGTCTAACCGTTAGTGAGCTTGGTTTTGCACTAGTAGTTCCAGTA TTTGACCTAATTTTTAGTTCTAGTCTTAGGTTAAGGTATTGTATAACATATTATATCTATCCATTGCATTTTCTGTTTTA GTTTTTTGATGCAAACCAATGTAACAGTAGATGTGCAATGAAGGATAGAAAGGGAATTGTTTGATTATATAAAAGAGAAA GGATGATTACAGTAGCACTCTACTACTCCAGAGCTAGGCTCCTATAGAGAAAGCATAATTCTCTATTCACTCTCACAATA ACAATACTCTCAGATACCCCCACATGCTAACCACAACTTTCCTTATATGCACAACCTCTCCCCTGATTCCCGTAACTAAC AAACCTATGACTCACTCTAATACTGCCAGCTCACTATTCTCTCTAGATGCTTCCTTTCTTATTCTTCCTGGCATACACCT GCCACACTTTGGGCCTCTGATCATTAGTATCAGCCCAATTCTGACTTGGAGGCCTATCATTTTATTTGATGTGTGATCTT GTCACTTTGTATGCCACCGCTTGTCCTTTTTATTGAACATGATATGGCATACAGTGTAGAATAACTCGACAACATAACTG GTATGTTTTTGCTATATTGACAGCCCTGTTGGAGAAAATAAGAAAAGCGGTGAAGTCTATAGACTATTTGATGTCGGCGG TCAGAGAAATGAGAGGCGAAAATGGATCCATCTGTTTGAAGGAGTTTCAGCTGTAATATTCTGTGCTGCAATTAGCGAGT ATATACTCTACCATTTGACTCTTTAGTCGTGTTTTCAATTTTCAAAAACATATGTAAATTTCTTGCGTGCACATCTGTTT TGAATTTACTGTATACCAAATCAAAAGGGTAGAGGGTCCAGTTGAAGTTACGAGTAAATTCTACTTTACAATATTACTTT GGAACTTTTTCAGTAGTTGCTAATTATCAAATTCATTATACTTGAAAGTGAAGTTTAAGCTCCTTCTAGTGATTATTTCG TGTATCCTTTCACTATTATAGGCAAGATCATCATAATTATGCAATGTGTAAATCTAAAGAAGTGTTGACATCACATTTTC CTTACAGGTACGATCAAACACTTTTTGAGGATGAAAACAAGAACAGAATGATGGAGACTAAGGAACTTTTTGAATGGGTC TTGAAGCAGCCATGTTTTGAGGTTTCCTTTTATATTCTTCTTTAACTGTTAACATTTACTACAATCATGTTGCAATCTCT TCTGTAACTTTTTTGCTCTTTCCTTTATATGAATAATATGATACTTGCTGTTGAGAGCTTTATGCTTCATTGACAGTTTA GATTTCTGCCTATCTCAGAAGATAATGATGTCTTTCTCTTTCATACACAGAAAACATCCTTCATGTTATTTCTAAACAAG TTTGACATATTTGAGAAGAAGATCCTGAAAGTAAGAACCATCAGAACATTGAAAACTTTGTCATTGGTGGAGGCTATTTA TCATTTTCAGTCTAATATCTTGCATTGTGCAGGTCCCTCTTAATGTTTGTGAGTGGTTCAAAGATTACCAGCCAGTTTCA ACAGGGAAACAGGAGATTGAGCACGCATATGAGTAAGCAACTAATCTATTCCTTAGGCATTTTGAATAAAGGATGTTGCT GAAGGCAAAGTAGATCCTGGCCAATGGAGGCCTTCCAAATTCAAAACATTGTTATGTTGTTCTGCATTTTTATTTCTACT GTATGACAAGCTAGAAGAAAGTTGATTGTTTTCCATCACAACATAGGAATATACTCATGTTGATATTTGAATATAATGTA ATAAACAAGCCACTAGGATTGGATTAATGGTGAGGGGTATTAGAATTCAGATTAGGCCTAACTCAACCACAAAAGCTAGC TCAGGGTGAGAATTGCTCTACCTTTCATAAGGACTTATTTGGCCATACCCAGGGACGGAACCAGGAAAATTAGAGACGGG GGGTGAAAATTTAACTTGGAAATACGAGACTGAGAAAGCCAGAACCAGGAACAGAGTGACAAGGGAATTAAAGAAGGCAG TGAGGGGCATAAAGTTGATGTAACTTTAGTGTGTGTTTAGATGCACATTAGAGAAATACGGTGAAGCTAAAATTACGGTG AACAATCACAAAAGCTAAAAAAATTTGCTTCAATCCACCATAATTTTAACTCCGCGTTTTTTTAATCATGTATGCAAACA TGCACTTGGCAATTTGAGTAGAACGTTTGGTTCTTTTTAACTCTGACTGCAGTTAACTTTTTATTTTTATTGAAATAGTG TTGTGTACTTGCTTTAAGCATGCAGTGATGGAAAATAAAATGTGAAGCTAGGAGTCTTATTAGCTGTAGGGACGGGACGG GACGAACATACAATTCTAAGTATATATATGCTAAGTTATCTTTGTGTTAGGGGGGCCATTGCCCCTTTTGGCTTAAGCTG GGTCCATCTCTGGCCATACCTCTAGTCAATGTAGGACTTGTCAACACACCTCACACCCAGAGCTGGACATCTGGAGTGTA AAGTTTGCAGGAATAAACATCTATGGGGCCCATTTATGGTAGGATAGTCTCTCGTTAAGAACCTTGGGAGAACCAACCAG AAAGCTAGCCTAGGTGTGAGGATTGCTCTACCCTTTTATAAGTACTAATTTGAGTATATCTCTAGTCAACGCGGGATCTC TAAACAAGGGGCTTGGGTAGTTTGCATGAAGTATTAAGTTTGAATTTCATTGTCACTATTGTAGAAAAAAAAACTGTAAA CAAGGTTATGATTGCTTACCTACCTTGAAAGGGCTATTACTATAAATTAACTTTATGATTAATTTTTCATATCCAATACA GCTAATGGACATGGATGAACTGTGTTTTTTTATTCCAGGTTTGTAAAGAAAAAGTTTGAAGAATCATATTTCCAGAACAC TGCCCCGGACCGTGTAGATCGCGTCTTCAAGATCTACCGGACCACTGCTCTTGATCAGAAGGTTGTGAAGAAGACATTCA AGCTTGTTGATGAGACATTGAGACGGCGGAATCTCTTTGAGGCTGGCTTGTTATGA
CDS sequence (LotjaGi5g1v0045000.5) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGCTGTCTTTTGTTACAGAAAATATGGGATTACTATGTAGCAAAAATCGCCGTTATAATGATGCTGACACTGAAGAAAA TGCACAGATAAAACTTTTGTTTCAAACTGGCTTTGACGAGGCAGAGCTAAAAAGCTACCAACCAGTCATACATGCTAATG TATATCAGACAATAAAATTACTGCATGACGGAGCAAAGGAGTTGGCCCAGAATGATGTTGATTTTTCAAAGTATGTTATA TCCGATGAAAACAAGGAAATTGGGGAAAAGTTATCAGAAATTGGGGGCAGGCTGGATTACCCCTGTCTCACCAAGGAACT AGCACTGGAAATAGAGAATTTATGGAAGGATGCTGCAATTCAGGAAACATATGCCCGCGGTAATGAGCTCCAAGTTCCAG ATTGTACCCACTATTTCATGGAAAATCTGCACAGACTGTCCGATGCAAATTATGTTCCAACAAAGGATGATGTTTTGTAT GCAAGAGTGCGTACCACTGGTGTTGTAGAGATCCAGTTCAGCCCTGTTGGAGAAAATAAGAAAAGCGGTGAAGTCTATAG ACTATTTGATGTCGGCGGTCAGAGAAATGAGAGGCGAAAATGGATCCATCTGTTTGAAGGAGTTTCAGCTGTAATATTCT GTGCTGCAATTAGCGAGTACGATCAAACACTTTTTGAGGATGAAAACAAGAACAGAATGATGGAGACTAAGGAACTTTTT GAATGGGTCTTGAAGCAGCCATGTTTTGAGAAAACATCCTTCATGTTATTTCTAAACAAGTTTGACATATTTGAGAAGAA GATCCTGAAAGTCCCTCTTAATGTTTGTGAGTGGTTCAAAGATTACCAGCCAGTTTCAACAGGGAAACAGGAGATTGAGC ACGCATATGAGTTTGTAAAGAAAAAGTTTGAAGAATCATATTTCCAGAACACTGCCCCGGACCGTGTAGATCGCGTCTTC AAGATCTACCGGACCACTGCTCTTGATCAGAAGGTTGTGAAGAAGACATTCAAGCTTGTTGATGAGACATTGAGACGGCG GAATCTCTTTGAGGCTGGCTTGTTATGA
Protein sequence (LotjaGi5g1v0045000.5) extracted from Lotus japonicus Gifu v1.2 Proteins.
MLSFVTENMGLLCSKNRRYNDADTEENAQIKLLFQTGFDEAELKSYQPVIHANVYQTIKLLHDGAKELAQNDVDFSKYVI SDENKEIGEKLSEIGGRLDYPCLTKELALEIENLWKDAAIQETYARGNELQVPDCTHYFMENLHRLSDANYVPTKDDVLY ARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVSAVIFCAAISEYDQTLFEDENKNRMMETKELF EWVLKQPCFEKTSFMLFLNKFDIFEKKILKVPLNVCEWFKDYQPVSTGKQEIEHAYEFVKKKFEESYFQNTAPDRVDRVF KIYRTTALDQKVVKKTFKLVDETLRRRNLFEAGLL
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| ProSiteProfiles | 9 | 355 | 347 | 76.756 | – | |
| SMART | 17 | 354 | 338 | 1.1E-131 | ||
| Gene3D | 29 | 331 | 303 | 7.0E-107 | – | |
| PANTHER | 29 | 355 | 327 | 8.8E-221 | ||
| PANTHER | 29 | 355 | 327 | 8.8E-221 | ||
| Pfam | 29 | 343 | 315 | 7.1E-81 | ||
| CDD | 29 | 349 | 321 | 2.67406E-126 | ||
| SUPERFAMILY | 38 | 163 | 126 | 5.76E-32 | ||
| Gene3D | 39 | 164 | 126 | 7.0E-107 | ||
| PRINTS | 48 | 61 | 14 | 2.2E-56 | ||
| PRINTS | 59 | 74 | 16 | 4.3E-38 | ||
| PRINTS | 63 | 77 | 15 | 2.2E-56 | ||
| PRINTS | 87 | 101 | 15 | 2.2E-56 | ||
| PRINTS | 151 | 173 | 23 | 4.3E-38 | ||
| SUPERFAMILY | 158 | 352 | 195 | 8.18E-36 | ||
| PRINTS | 171 | 186 | 16 | 2.2E-56 | ||
| PRINTS | 186 | 203 | 18 | 4.3E-38 | ||
| PRINTS | 208 | 236 | 29 | 4.3E-38 | ||
| PRINTS | 241 | 252 | 12 | 2.2E-56 | ||
| PRINTS | 254 | 263 | 10 | 4.3E-38 | ||
| PRINTS | 290 | 305 | 16 | 2.2E-56 | ||
| PRINTS | 307 | 319 | 13 | 2.2E-56 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | G protein-coupled receptor binding | Interacting selectively and non-covalently with a G protein-coupled receptor. | ||
| Molecular function | GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + phosphate. | ||
| Cellular component | Heterotrimeric G-protein complex | Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. | ||
| Biological process | Signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. | ||
| Biological process | G protein-coupled receptor signaling pathway | A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576). | ||
| Biological process | Adenylate cyclase-modulating G protein-coupled receptor signaling pathway | The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP). | ||
| Molecular function | Guanyl nucleotide binding | Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate. | ||
| Molecular function | G-protein beta/gamma-subunit complex binding | Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits. |
Expression pattern of LotjaGi5g1v0045000.5, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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