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| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0565200 |
| Transcript ID | LotjaGi1g1v0565200.1 |
| Related isoforms 7 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K754|I1K754_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:109856441..109861623) extracted from Lotus japonicus Gifu genome v1.2.
ATCATTGCGAGATTTAAAGATATGGATTGGACTACGATTGAGTGGTGGATCAGCCCATACATTACAATCCATATAATTTG GATCCATTGACCCAAAAAAGAAAAGAAAAACCTTTTTTTGTTTTCAAACTATCTTCTGTTCTTCTACCCAGTGTCGCAAA ACCCCTGATCCTGAATGCTTTCCATAATCTGATTACTGTCTTCAGTTCAGTGTTTTGCATCGTCATAATCGGTTATCAAT TTTTTGAAAGGGAAGAAGTATCGACCCAAACGCCCCCCTCAACCCCGCCAGCACCACCTCCTACAGGTATGCCTATTATA TAAGGATAGCTCTACCATTTACATAGTTATGTTAGCTAGTTTATATATGACATGATATTTCATTCATTTCTGTTTCTACT GAAATATTTTAATTCTTCCCAGATATCATCGTCATGTCTTTAAGACTATAACTCTGCTCTTCTCAATTTAAAAAATATGA TCAATTCATACTCACGATTATGGAAGGTATATATTTCCTTTCATTCTAACATGTAGTATATAGCTTATAGGTATCCAATA ATATCACACCATTATTATTAGACTAATTCGCCACCAAAATGCTAGGGTAATACTAACTATTATGCTGTCACAATGTAAAT TGCTTAGGTCTTTTCTGCATATCCTCATTTTTTTTTTCTTATGCTGTATGTATGCATTTCATCTGATCTTGTTTTGCATG AGTGGTGCCACTTATAATTATTAACTTTGATTTATTACGTTTTTGAGTTTCAGATTCCACTGCAGTTCCCGAAGAATAGG CCGTGCAGCCCTTGTTTTCAGACGGTGTCTTCGAGCTTCTGTCGGTTTTTGAGTTCTATGATGACTGGTGATTCTTTTGT AGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTACCAAGTGGTGGTTGCTGCCA CCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCAAGTTTTTTAAGGAGATCACT ACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAGAGTATCCCTCTTAAGTATAG GCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAACGGCAGAGAATGTTGTGATTT GTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTGAGAAAGTATTTGTCATAGGA GGCGGTCAGATATTTAGGTATATGTTCTTCTCCCCCTTCTTGTGCTCCATCCTTTTCTGCTATAGACTTATGGCTGATAA TTTCAATGTACAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACTGAAATTCATGCAAGCATTGAGTGT GACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTTTCCTAAGGTGGAAAACGACATCCG CTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTCAGAATACTGATCCACTTTTTGATA ATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATGATTCTTCAGAGACATGAGGAATAC ATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAGGACAGGGACTGGTACCTTGTCAAA ATTTGGTTGCCAGGTAATGTGTCAATTGATATATTGAGTTTATCATAATTTATATGCTGACTTTATCTCTATAATTCTAC AGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCAAGGCATGCAATTGTGGTTATGGTTTAGGATATGTT TTTAATCTACTGTGCAAAACATTATTTTCTTTTTAATTACTTTGGATGTTTACGGTTAAAGAGGAATGTCTATTTGTACA TTTTGATAGAGAAGCTGACATGATTTCTTCATTGGGTTTCTAGAAAGTATTTTGGCGAGGGGTTGTTGAAGAACTTCTTT GGTTTATCAGTGGCTCAACAAATGCCAAGGTAATTATAACTTTTGACAATCTTTTCTACACACATGAATATGGTATGTAC TAGTCCCTTAGGTTTGGTTATGTGGTGTTGAACAGTAAAATCTGGTTGTAATTCTTTCTAGCTCCTTCGTTTTTGTGCTA CTTTGTTGGTATAGTAGATAAGGACATACGGTTATTATGACCTATATTCAGAAAGCATTCTATATTGACAGGTGTTGCAG GAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGGCAAGCATGATTGTCATTTGTTCAACT TTTAAATACAGATTGTACACTTATCTTCTTCTTGCAGTTACTAACTGGCATTACATTTTTTTACTACAGTATTGGTTTGA CAGAGAGGGAGGAGGGTGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTGCCAGGTAGGTGGACAACTAG TTATTTTTCTCAGGTGGTGAATATTTAATAAACTGTTTAATGTGGCATTGCTCTGCTCTTTACTTTCCATCTTACATTTT ATAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCAGCTTTTAGATGTTATTAACAAGATAAAGCAT AATCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATCTTAAATTGATGGCACTTCCACCCTGCCACAT GTTTGCACAGGTCTGCAGCTTTAGTTAGGGTTCTCTTTGAAAAGTCTCCCTCTCCTTTTTAAATCTTTTAATTTTTGTTA ATTTTTAATTTGTAACTTGCAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTATCAGCGATCTGCTGACATGG GCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATGTTTGTGGTATGTAAATGATC AAAGCATTTGCTATAGACTTAAATATTATCATGTGTATACTTCATCGTAAATGTTGAGGTTTCCAGCTGTAATGAGAGGT GATGTAATGCCATTTCATTTTGTTGTAAATGGCTTTAAGCATAATAATTGGTGGTGGTTCTCATAGATTTATTGTCATGA TCCAATTTATTTTCTTTACAGGGGGGTGGGGGGTAATAATATGACTTTAATGTGCTCAGCTCAGCCCAAGCCTGATTTTA TTTGTTTAACTAAGATTGACGCTTGAAACTTCGCCTCAGTTGGTTTGTTAAAAAGTTAAAACTAATATTTTCTTTTGGAC TTCAGTCATGTGAAGAAGTTGATTAGTATCTTCTGAAGTTTTGCATTCAAGATTATGAAGCTTTTATTTTTCTGTTGTTT TTTTTGGTTATATTTTATCACATAATGCACTTTCCATCATTTTTATAGCTTTTTTGTTAGGGTTGTTTCAGAAGAAATTT GTCAGTAAGTTTTTGTTTCACCACTGAGGGTTGGTTGTAGTTGGGTTCAGGTTCGAGAAGTTTATTGGGTTGATAAGATT ACAATTGAAAAAATACAGCTCCAAAAAGTGCTTTAAAAATTGACTAAACAAATCCTTTTTTTTTTTCATTTCAGAACTCG TTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGGCCTTTGCAGGAGCAGCTTCTT AACCTACCTAAACCTTTTCCTGTATGTGTGAATACTTTAGAAAATTATTTGCTTTACATAATTGGCCACAAATATTTTAC CATTTATCACTCCTTTAGATTTGTGTCTTTTGACTCTTTACTCTTTAGTCTTGATGACTATCTTAACTCCAATGCAGACT TTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCTGCTGATTTCAAGCTTGTAGGCTATAATCCTCACCA GAAGATTGAGATGAAGATGGCAGTTTAAAACCTGTTAGATTCTTTCTCCCTTCTTCAGATTGTTTCTGGTTTTTGAAATT GTAAGTTTGCAGTTGTTTTGCTAGACAAATTTTCACCTTCAGAAGATTTATCAAACGTGGTTTGGTGCTTTCTTATGGTC CATGAGCCGTAGAACCATGTTGAGCATGTATGCTAAAGGGATTAGGATCCTCTCATATTAGATAACAATATCAAGTGAAA CATTTTTTATCTTTTTCTTCATAAATATTCAGAGGATTCCACCTAATCAATACTTATGAAGTGAGATAGACACAAAAGTT TCAATATAATAGTGTCATGTGAAGATTCCACATGAGAGGATCGTAATCCATCTTTGAAAGAAAGGGAAGATCTGTGTGGG TGTTTGCTAAAAGCGAGAAACTTATGGCTTCAAGGATGATGTTGTACAAAGGAATTGCTACTGCCAATGGCTCCCTTTAC CATTTGCTTTGTTTTTTATGAACTCATGTTCAAAATTAAATAATGTCAAAATTGCTCTTTTTTGTTTCTTGGGGGTAATT TAGTGAACATGATAGCAGCATGTAATCCAATCTGATGTATATAAGCTATATTTTATTAGATTAATCTCAATCACTGATTA CAAAGATCAAGTGCCTATAATTGTGCAGGAGAGAGTTGTAGAGAACCTCTGCTACATAGATCCAAATTGCACACACACGC ACACATATATATAATAGGAATTATTATTATCCATAGAGGCTCCTTTCATGAAGGCTTCAAGTGCTTTTTGTGATGTGCAT AACTAGATTAGCAAGCTCCAATTTCTCTACCCCATGAAGTTTGACAATCTTGTTTTTGAACCTGCGGAACAATTCATCCA TGATTGCTTCACCAAACTCTGACTTCAGAATTGACTCTGCAACAGCTCTTATGTACTTTGCCACTGCCTCAGCTCTTGTG TCTTCATCAATATCATCGCTCACGTTGATGTTTTTGATCCAATCCGTTCTTATTGTCTCCAACCTTTGAATATCAAAAGA CCCTTCTTCCTCAATTACTTGTCGTATCTCCTCAGCAGTAGGACAGTATGACGGTATGTTAAAAGCGTCCAATTTTGCCT TCTCAATCAAATTCTGCACCAAAAGCAAGTTTTAGTGTGTTTGGTTTCATGTTTGCGAACCTC
CDS sequence (LotjaGi1g1v0565200.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGATCAATTCATACTCACGATTATGGAAGATTCCACTGCAGTTCCCGAAGAATAGGCCGTGCAGCCCTTGTTTTCAGAC GGTGTCTTCGAGCTTCTGTCGGTTTTTGAGTTCTATGATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATG GCAGTATCAACCCACTACCTAATCTGCAGAGGACTTACCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAG GATGGAAAATTACCCTGGAGATTATTTACCGATCTCAAGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAA GAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAGAGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATG TTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAACGGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTA GAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTGAGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGAGAAGT TCTTAATGCACCTGGATGTGAAGCTATCCACTTCACTGAAATTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAG TTGATTCCACTAAATATCAGTTATGGTACTCATCCTTTCCTAAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTAT GTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTCAGAATACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAA GTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATGATTCTTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTC AAGAAATCATATCTGAAGGTACAACTAAGGATGATAGGACAGGGACTGGTACCTTGTCAAAATTTGGTTGCCAGATGAGG TTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCAAGAAAGTATTTTGGCGAGGGGTTGTTGAAGAACTTCTTTGGTT TATCAGTGGCTCAACAAATGCCAAGGTGTTGCAGGAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACC TGGATAGTATTGGTTTGACAGAGAGGGAGGAGGGTGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTGCC AGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCAGCTTTTAGATGTTATTAACAAGATAAAGCATAA TCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATCTTAAATTGATGGCACTTCCACCCTGCCACATGT TTGCACAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTATCAGCGATCTGCTGACATGGGCCTGGGCGTGCCA TTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATGTTTGTGAACTCGTTCCAGGTGATTTCGTCCATGT TATTGGGGATGCACATGTTTACCACAATCATGTGCGGCCTTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTA CTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCTGCTGATTTCAAGCTTGTAGGCTATAATCCTCAC CAGAAGATTGAGATGAAGATGGCAGTTTAA
Protein sequence (LotjaGi1g1v0565200.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MINSYSRLWKIPLQFPKNRPCSPCFQTVSSSFCRFLSSMMTGDSFVVSSGNGNGSINPLPNLQRTYQVVVAATKDMGIGK DGKLPWRLFTDLKFFKEITTATSDPGKKNAIVMGRKTWESIPLKYRPLPGRLNVVLTRSGSFDIGTAENVVICGSISSAL ELLAASPYCLSIEKVFVIGGGQIFREVLNAPGCEAIHFTEIHASIECDTFMPPVDSTKYQLWYSSFPKVENDIRYSFATY VRVQSSAAESLSQNTDPLFDNNSDSLKFEVQNFDFLPEMILQRHEEYMYLRLIQEIISEGTTKDDRTGTGTLSKFGCQMR FNLRRSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASREYLDSIGLTEREEGDLGPVYGFQWRHFGA RYSDMHKDYSGQGYDQLLDVINKIKHNPNDRRIILSAWNPVDLKLMALPPCHMFAQFFVANGELSCQMYQRSADMGLGVP FNIASYALLTCMIAHVCELVPGDFVHVIGDAHVYHNHVRPLQEQLLNLPKPFPTLKINSEKKDIDSFVAADFKLVGYNPH QKIEMKMAV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| SUPERFAMILY | 39 | 242 | 204 | 8.25E-59 | ||
| PIRSF | 49 | 569 | 521 | 1.8E-257 | ||
| Gene3D | 53 | 243 | 191 | 2.1E-59 | ||
| PANTHER | 62 | 569 | 508 | 1.6E-288 | – | |
| PANTHER | 62 | 569 | 508 | 1.6E-288 | – | |
| ProSiteProfiles | 65 | 242 | 178 | 51.57 | ||
| Pfam | 67 | 242 | 176 | 2.7E-39 | ||
| CDD | 69 | 241 | 173 | 2.18093E-60 | ||
| ProSitePatterns | 77 | 99 | 23 | - | ||
| SUPERFAMILY | 274 | 569 | 296 | 1.96E-137 | ||
| Gene3D | 275 | 569 | 295 | 4.2E-142 | ||
| Hamap | 286 | 569 | 284 | 35.821 | ||
| Pfam | 288 | 569 | 282 | 3.2E-112 | ||
| TIGRFAM | 288 | 569 | 282 | 9.8E-104 | ||
| CDD | 289 | 522 | 234 | 8.11366E-121 | ||
| PRINTS | 327 | 348 | 22 | 9.0E-53 | ||
| PRINTS | 420 | 439 | 20 | 9.0E-53 | ||
| ProSitePatterns | 431 | 459 | 29 | - | ||
| PRINTS | 446 | 461 | 16 | 9.0E-53 | ||
| PRINTS | 464 | 490 | 27 | 9.0E-53 | ||
| PRINTS | 502 | 519 | 18 | 9.0E-53 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. | ||
| Molecular function | Thymidylate synthase activity | Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. | ||
| Biological process | DTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). | ||
| Biological process | One-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. | ||
| Biological process | Tetrahydrofolate biosynthetic process | The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi1g1v0565200.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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