Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0565200 |
| Transcript ID | LotjaGi1g1v0565200.7 |
| Related isoforms 7 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:109857301..109860468) extracted from Lotus japonicus Gifu genome v1.2.
ATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTA CCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCA AGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAG AGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAAC GGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTG AGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGGTATATGTTCTTCTCCCCCTTCTTGTGCTCCATCCTTTTCTGC TATAGACTTATGGCTGATAATTTCAATGTACAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACTGAAA TTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTTTCCT AAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTCAGAA TACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATGATTC TTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAGGACA GGGACTGGTACCTTGTCAAAATTTGGTTGCCAGGTAATGTGTCAATTGATATATTGAGTTTATCATAATTTATATGCTGA CTTTATCTCTATAATTCTACAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCAAGGCATGCAATTGTG GTTATGGTTTAGGATATGTTTTTAATCTACTGTGCAAAACATTATTTTCTTTTTAATTACTTTGGATGTTTACGGTTAAA GAGGAATGTCTATTTGTACATTTTGATAGAGAAGCTGACATGATTTCTTCATTGGGTTTCTAGAAAGTATTTTGGCGAGG GGTTGTTGAAGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGGTAATTATAACTTTTGACAATCTTTTCTACA CACATGAATATGGTATGTACTAGTCCCTTAGGTTTGGTTATGTGGTGTTGAACAGTAAAATCTGGTTGTAATTCTTTCTA GCTCCTTCGTTTTTGTGCTACTTTGTTGGTATAGTAGATAAGGACATACGGTTATTATGACCTATATTCAGAAAGCATTC TATATTGACAGGTGTTGCAGGAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGGCAAGCA TGATTGTCATTTGTTCAACTTTTAAATACAGATTGTACACTTATCTTCTTCTTGCAGTTACTAACTGGCATTACATTTTT TTACTACAGTATTGGTTTGACAGAGAGGGAGGAGGGTGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTG CCAGGTAGGTGGACAACTAGTTATTTTTCTCAGGTGGTGAATATTTAATAAACTGTTTAATGTGGCATTGCTCTGCTCTT TACTTTCCATCTTACATTTTATAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCAGCTTTTAGATG TTATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATCTTAAATTGATG GCACTTCCACCCTGCCACATGTTTGCACAGGTCTGCAGCTTTAGTTAGGGTTCTCTTTGAAAAGTCTCCCTCTCCTTTTT AAATCTTTTAATTTTTGTTAATTTTTAATTTGTAACTTGCAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTA TCAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATG TTTGTGGTATGTAAATGATCAAAGCATTTGCTATAGACTTAAATATTATCATGTGTATACTTCATCGTAAATGTTGAGGT TTCCAGCTGTAATGAGAGGTGATGTAATGCCATTTCATTTTGTTGTAAATGGCTTTAAGCATAATAATTGGTGGTGGTTC TCATAGATTTATTGTCATGATCCAATTTATTTTCTTTACAGGGGGGTGGGGGGTAATAATATGACTTTAATGTGCTCAGC TCAGCCCAAGCCTGATTTTATTTGTTTAACTAAGATTGACGCTTGAAACTTCGCCTCAGTTGGTTTGTTAAAAAGTTAAA ACTAATATTTTCTTTTGGACTTCAGTCATGTGAAGAAGTTGATTAGTATCTTCTGAAGTTTTGCATTCAAGATTATGAAG CTTTTATTTTTCTGTTGTTTTTTTTGGTTATATTTTATCACATAATGCACTTTCCATCATTTTTATAGCTTTTTTGTTAG GGTTGTTTCAGAAGAAATTTGTCAGTAAGTTTTTGTTTCACCACTGAGGGTTGGTTGTAGTTGGGTTCAGGTTCGAGAAG TTTATTGGGTTGATAAGATTACAATTGAAAAAATACAGCTCCAAAAAGTGCTTTAAAAATTGACTAAACAAATCCTTTTT TTTTTTCATTTCAGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGGC CTTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTGTATGTGTGAATACTTTAGAAAATTATTTGCTTTACATA ATTGGCCACAAATATTTTACCATTTATCACTCCTTTAGATTTGTGTCTTTTGACTCTTTACTCTTTAGTCTTGATGACTA TCTTAACTCCAATGCAGACTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCTGCTGATTTCAAGCTT GTAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
CDS sequence (LotjaGi1g1v0565200.7) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTA CCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCA AGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAG AGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAAC GGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTG AGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACT GAAATTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTT TCCTAAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTC AGAATACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATG ATTCTTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAG GACAGGGACTGGTACCTTGTCAAAATTTGGTTGCCAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCA AGAAAGTATTTTGGCGAGGGGTTGTTGAAGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGGTGTTGCAGGAA AAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGTATTGGTTTGACAGAGAGGGAGGAGGGTGA CTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTGCCAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAG GATATGATCAGCTTTTAGATGTTATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGGAAT CCAGTTGATCTTAAATTGATGGCACTTCCACCCTGCCACATGTTTGCACAGTTCTTTGTAGCAAATGGAGAATTATCATG TCAAATGTATCAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGA TTGCTCATGTTTGTGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGG CCTTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTACTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTC TTTTGTAGCTGCTGATTTCAAGCTTGTAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
Protein sequence (LotjaGi1g1v0565200.7) extracted from Lotus japonicus Gifu v1.2 Proteins.
MTGDSFVVSSGNGNGSINPLPNLQRTYQVVVAATKDMGIGKDGKLPWRLFTDLKFFKEITTATSDPGKKNAIVMGRKTWE SIPLKYRPLPGRLNVVLTRSGSFDIGTAENVVICGSISSALELLAASPYCLSIEKVFVIGGGQIFREVLNAPGCEAIHFT EIHASIECDTFMPPVDSTKYQLWYSSFPKVENDIRYSFATYVRVQSSAAESLSQNTDPLFDNNSDSLKFEVQNFDFLPEM ILQRHEEYMYLRLIQEIISEGTTKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQE KGIHIWDGNASREYLDSIGLTEREEGDLGPVYGFQWRHFGARYSDMHKDYSGQGYDQLLDVINKIKHNPNDRRIILSAWN PVDLKLMALPPCHMFAQFFVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCELVPGDFVHVIGDAHVYHNHVR PLQEQLLNLPKPFPTLKINSEKKDIDSFVAADFKLVGYNPHQKIEMKMAV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PIRSF | 12 | 530 | 519 | 1.4E-257 | ||
| Gene3D | 14 | 204 | 191 | 1.9E-59 | ||
| SUPERFAMILY | 18 | 203 | 186 | 1.96E-58 | ||
| PANTHER | 23 | 530 | 508 | 1.2E-288 | – | |
| PANTHER | 23 | 530 | 508 | 1.2E-288 | – | |
| ProSiteProfiles | 26 | 203 | 178 | 51.57 | ||
| Pfam | 28 | 203 | 176 | 2.3E-39 | ||
| CDD | 30 | 202 | 173 | 1.93316E-60 | ||
| ProSitePatterns | 38 | 60 | 23 | - | ||
| SUPERFAMILY | 235 | 530 | 296 | 1.7E-137 | ||
| Gene3D | 236 | 530 | 295 | 3.5E-142 | ||
| Hamap | 247 | 530 | 284 | 35.821 | ||
| Pfam | 249 | 530 | 282 | 2.7E-112 | ||
| TIGRFAM | 249 | 530 | 282 | 8.2E-104 | ||
| CDD | 250 | 483 | 234 | 6.80707E-121 | ||
| PRINTS | 288 | 309 | 22 | 7.0E-53 | ||
| PRINTS | 381 | 400 | 20 | 7.0E-53 | ||
| ProSitePatterns | 392 | 420 | 29 | - | ||
| PRINTS | 407 | 422 | 16 | 7.0E-53 | ||
| PRINTS | 425 | 451 | 27 | 7.0E-53 | ||
| PRINTS | 463 | 480 | 18 | 7.0E-53 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. | ||
| Molecular function | Thymidylate synthase activity | Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. | ||
| Biological process | DTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). | ||
| Biological process | One-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. | ||
| Biological process | Tetrahydrofolate biosynthetic process | The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi1g1v0565200.7, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
Loading expression data from ljgea-geneid. Please wait…