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IPR000804 is a Clathrin adaptor complex, small chain.
<p>Proteins synthesized on the ribosome and processed in the endoplasmic reticulum are transported from the Golgi apparatus to the trans-Golgi network (TGN), and from there via small carrier vesicles to their final destination compartment. This traffic is bidirectional, to ensure that proteins required to form vesicles are recycled. Vesicles have specific coat proteins (such as clathrin or coatomer) that are important for cargo selection and direction of transfer [[cite:PUB00035769]].</p> <p>This entry represents the small sigma subunit of various adaptins from different AP clathrin adaptor complexes (including AP1, AP2, AP3 and AP4), and the zeta subunit of various coatomer (COP) adaptors. The small sigma subunit of AP proteins have been characterised in several species [[cite:PUB00001249], [cite:PUB00000652], [cite:PUB00001249], [cite:PUB00035771]]. The sigma subunit plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The zeta subunit of coatomers (zeta-COP) is required for coatomer binding to Golgi membranes and for coat-vesicle assembly [[cite:PUB00003074], [cite:PUB00035772]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. | ||
| Biological process | Vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. | ||
| Cellular component | Membrane coat | Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: AP-3 complex subunit sigma-like [Cicer arietinum] gi|502153217|ref|XP_004509260.1| | 11 | ||
| – | PREDICTED: AP-3 complex subunit sigma-like [Cicer arietinum] gi|502153217|ref|XP_004509260.1| | 12 | ||
| – | PREDICTED: AP-1 complex subunit sigma-1-like [Cicer arietinum] gi|502134135|ref|XP_004502012.1| | 11 | ||
| – | PREDICTED: AP-1 complex subunit sigma-1-like [Cicer arietinum] gi|502134135|ref|XP_004502012.1| | 10 | ||
| – | AP-1 complex subunit sigma-1; TAIR: AT2G17380.1 associated protein 19; Swiss-Prot: sp|Q8LEZ8|AP1S1_ARATH AP-1 complex subunit sigma-1; TrEMBL-Plants: tr|I3T1A3|I3T1A3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0003000 | 12 | ||
| – | AP-1 complex subunit sigma-1; TAIR: AT2G17380.1 associated protein 19; Swiss-Prot: sp|Q8LEZ8|AP1S1_ARATH AP-1 complex subunit sigma-1; TrEMBL-Plants: tr|I3T1A3|I3T1A3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0003000 | 12 | ||
| – | AP-1 complex subunit sigma-1; TAIR: AT2G17380.1 associated protein 19; Swiss-Prot: sp|Q8LEZ8|AP1S1_ARATH AP-1 complex subunit sigma-1; TrEMBL-Plants: tr|I3S6L2|I3S6L2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0056300 | 13 | ||
| – | AP-1 complex subunit sigma-like protein; TAIR: AT3G50860.1 Clathrin adaptor complex small chain family protein; Swiss-Prot: sp|Q8VZ37|AP3S_ARATH AP-3 complex subunit sigma; TrEMBL-Plants: tr|A0A151SEJ3|A0A151SEJ3_CAJCA AP-3 complex subunit sigma-2; Found in the gene: LotjaGi1g1v0416600 | 12 | ||
| – | AP-1 complex subunit sigma-like protein; TAIR: AT3G50860.1 Clathrin adaptor complex small chain family protein; Swiss-Prot: sp|Q8VZ37|AP3S_ARATH AP-3 complex subunit sigma; TrEMBL-Plants: tr|A0A072TSQ8|A0A072TSQ8_MEDTR AP-1 complex subunit sigma-like protein; Found in the gene: LotjaGi1g1v0416600 | 12 | ||
| – | AP-1 complex subunit sigma-like protein; TAIR: AT3G50860.1 Clathrin adaptor complex small chain family protein; Swiss-Prot: sp|Q8VZ37|AP3S_ARATH AP-3 complex subunit sigma; TrEMBL-Plants: tr|A0A151SEJ3|A0A151SEJ3_CAJCA AP-3 complex subunit sigma-2; Found in the gene: LotjaGi1g1v0416600 | 12 | ||
| – | AP-1 complex subunit sigma-like protein; TAIR: AT3G50860.1 Clathrin adaptor complex small chain family protein; Swiss-Prot: sp|Q8VZ37|AP3S_ARATH AP-3 complex subunit sigma; TrEMBL-Plants: tr|A0A151SEJ3|A0A151SEJ3_CAJCA AP-3 complex subunit sigma-2; Found in the gene: LotjaGi1g1v0416600 | 12 | ||
| – | AP-1 complex subunit sigma-like protein; TAIR: AT3G50860.1 Clathrin adaptor complex small chain family protein; Swiss-Prot: sp|Q8VZ37|AP3S_ARATH AP-3 complex subunit sigma; TrEMBL-Plants: tr|A0A151SEJ3|A0A151SEJ3_CAJCA AP-3 complex subunit sigma-2; Found in the gene: LotjaGi4g1v0117300 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd14834 | CDD | 1 | 8.33 |