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IPR001585 is a Transaldolase/Fructose-6-phosphate aldolase.
<p>Transaldolase (TAL) is an enzyme of the pentose phosphate pathway (PPP) found almost ubiquitously in the three domains of life (Archaea, Bacteria, and Eukarya). TAL shares a high degree of structural similarity and sequence identity with fructose-6-phosphate aldolase (FSA) [[cite:PUB00053971]]. They both belong to the class I aldolase family [[cite:PUB00076746]]. Their protein structures have been revealed [[cite:PUB00076745]].</p> <p>Transaldolase ([ec:2.2.1.2]) catalyses the reversible transfer of a three-carbon ketol unit from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate to form erythrose 4-phosphate and fructose 6-phosphate. This enzyme, together with transketolase, provides a link between the glycolytic and pentose-phosphate pathways. Transaldolase is an enzyme of about 34kDa whose sequence has been well conserved throughout evolution. A lysine has been implicated [[cite:PUB00005649]] in the catalytic mechanism of the enzyme; it acts as a nucleophilic group that attacks the carbonyl group of fructose-6-phosphate.</p> <p>Fructose-6-phosphate aldolase was originally thought to be transaldolases or transaldolase-related proteins. However, they perform a novel reaction, the cleavage or formation of fructose 6-phosphate [[cite:PUB00053971]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: transaldolase-like [Glycine max] gi|356523949|ref|XP_003530596.1| | 7 | ||
| – | PREDICTED: transaldolase-like [Glycine max] gi|356523949|ref|XP_003530596.1| | 7 | ||
| – | PREDICTED: transaldolase-like [Glycine max] gi|356523949|ref|XP_003530596.1| | 7 | ||
| – | PREDICTED: transaldolase-like [Glycine max] gi|356514222|ref|XP_003525805.1| | 14 | ||
| – | PREDICTED: transaldolase-like [Cicer arietinum] gi|502090152|ref|XP_004489137.1| | 9 | ||
| – | PREDICTED: transaldolase-like [Cicer arietinum] gi|502090152|ref|XP_004489137.1| | 14 | ||
| – | PREDICTED: transaldolase-like [Glycine max] gi|356512932|ref|XP_003525168.1| | 16 | ||
| – | PREDICTED: transaldolase-like [Cicer arietinum] gi|502139560|ref|XP_004503815.1| | 16 | ||
| – | PREDICTED: transaldolase-like [Cicer arietinum] gi|502139560|ref|XP_004503815.1| | 16 | ||
| – | Transaldolase; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|A9WT40|TAL_RENSM Transaldolase; TrEMBL-Plants: tr|I1KZJ0|I1KZJ0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0552500 | 14 | ||
| – | Transaldolase; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|A9WT40|TAL_RENSM Transaldolase; TrEMBL-Plants: tr|I1KZJ0|I1KZJ0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0552500 | 14 | ||
| – | Transaldolase family protein; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|Q829U5|TAL2_STRAW Transaldolase 2; TrEMBL-Plants: tr|A0A0R0JYG0|A0A0R0JYG0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0017700 | 9 | ||
| – | Transaldolase family protein; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|Q829U5|TAL2_STRAW Transaldolase 2; TrEMBL-Plants: tr|A0A0R0JYG0|A0A0R0JYG0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0017700 | 9 | ||
| – | Transaldolase; TAIR: AT1G12230.1 Aldolase superfamily protein; Swiss-Prot: sp|Q65PZ8|TAL_MANSM Transaldolase; TrEMBL-Plants: tr|I3TA48|I3TA48_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0208800 | 14 | ||
| – | Transaldolase; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|Q829U5|TAL2_STRAW Transaldolase 2; TrEMBL-Plants: tr|K7KRC0|K7KRC0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0422700 | 19 | ||
| – | Transaldolase; TAIR: AT5G13420.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|A9WT40|TAL_RENSM Transaldolase; TrEMBL-Plants: tr|K7KRC0|K7KRC0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0422700 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00955 | CDD | 1 | 6.25 |