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IPR002734 is a Bacterial bifunctional deaminase-reductase, C-terminal.
<p>This domain is found in the C terminus of the bifunctional deaminase-reductase of Escherichia coli, Bacillus subtilis and other bacteria in combination with [interpro:IPR002125] that catalyses the second and third steps in the biosynthesis of riboflavin, i.e., the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (deaminase) and the subsequent reduction of the ribosyl side chain (reductase) [[cite:PUB00006368]]. The domain is also present in some HTP reductases from archaea and fungi.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity | Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH. | ||
Biological process | Riboflavin biosynthetic process | The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). | ||
Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: riboflavin biosynthesis protein RibD-like [Cicer arietinum] gi|502105588|ref|XP_004492842.1| | 28 | ||
– | Riboflavin biosynthesis protein RibD; TAIR: AT3G47390.2 cytidine/deoxycytidylate deaminase family protein; Swiss-Prot: sp|Q9STY4|RIBRX_ARATH Riboflavin biosynthesis protein PYRR, chloroplastic; TrEMBL-Plants: tr|A0A1J7G1G5|A0A1J7G1G5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0486000 | 30 | ||
– | Riboflavin biosynthesis protein RibD; TAIR: AT3G47390.2 cytidine/deoxycytidylate deaminase family protein; Swiss-Prot: sp|K7WIZ6|RIBRX_MAIZE Riboflavin biosynthesis protein PYRR, chloroplastic; TrEMBL-Plants: tr|I1N3Z5|I1N3Z5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0486000 | 18 | ||
– | Riboflavin biosynthesis protein RibD; TAIR: AT3G47390.2 cytidine/deoxycytidylate deaminase family protein; Swiss-Prot: sp|K7WIZ6|RIBRX_MAIZE Riboflavin biosynthesis protein PYRR, chloroplastic; TrEMBL-Plants: tr|A0A1J7G1G5|A0A1J7G1G5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0486000 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd15457 | CDD | 1 | 25.00 |