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IPR002816 is a TraB/PrgY/GumN family.
<p>This entry includes Tiki1/2 from humans, TraB/PrgY from the gut flora Enterococcus faecalis and gumN from the plant pathogen Xanthomonas. Tiki1 is homologous to TraB/PrgY. They have a pair of widely spaced GX2H motifs and a conserved glutamate. From the structural study, this group of proteins have been identified as an ancient metalloprotease clan with a common protein architecture -cobbled from the folds of the EreA/ChaN/PMT group- that mediates proteolytic activities [[cite:PUB00095434]].</p> <p>Tiki1 is a membrane-associated protease that inhibits Wnt via the cleavage of its amino terminus, diminishing Wnt's binding to receptors [[cite:PUB00091071]].</p> <p>TraB/PrgY is an inhibitor peptide that may act as a protease to inactivate the mating pheromone [[cite:PUB00095434]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: traB domain-containing protein-like isoform X1 [Cicer arietinum] gi|502119410|ref|XP_004496610.1| | 4 | ||
| – | PREDICTED: traB domain-containing protein-like [Glycine max] gi|356544828|ref|XP_003540849.1| | 4 | ||
| – | PREDICTED: traB domain-containing protein-like [Cicer arietinum] gi|502167085|ref|XP_004514053.1| | 9 | ||
| – | PREDICTED: traB domain-containing protein-like isoform X2 [Cicer arietinum] gi|502119413|ref|XP_004496611.1| | 4 | ||
| – | TraB family protein; TAIR: AT1G05270.1 TraB family protein; Swiss-Prot: sp|Q58760|Y1365_METJA Uncharacterized protein MJ1365; TrEMBL-Plants: tr|A0A151S6A3|A0A151S6A3_CAJCA TraB domain-containing protein; Found in the gene: LotjaGi3g1v0463500_LC | 5 | ||
| – | TraB family protein; TAIR: AT1G05270.1 TraB family protein; Swiss-Prot: sp|Q58DF3|TRABD_BOVIN TraB domain-containing protein; TrEMBL-Plants: tr|V7AG78|V7AG78_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0463600 | 10 | ||
| – | TraB family protein; TAIR: AT1G05270.1 TraB family protein; Swiss-Prot: sp|Q58760|Y1365_METJA Uncharacterized protein MJ1365; TrEMBL-Plants: tr|A0A072UIY1|A0A072UIY1_MEDTR TraB family protein; Found in the gene: LotjaGi3g1v0496100_LC | 5 | ||
| – | TraB family protein; TAIR: AT5G52030.1 TraB family protein; Swiss-Prot: sp|Q99JY4|TRABD_MOUSE TraB domain-containing protein; TrEMBL-Plants: tr|I1LDV2|I1LDV2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0304600 | 11 | ||
| – | TraB family protein; TAIR: AT5G52030.1 TraB family protein; Swiss-Prot: sp|Q99JY4|TRABD_MOUSE TraB domain-containing protein; TrEMBL-Plants: tr|K7LL49|K7LL49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0304600 | 5 | ||
| – | TraB family protein; TAIR: AT5G52030.1 TraB family protein; Swiss-Prot: sp|Q99JY4|TRABD_MOUSE TraB domain-containing protein; TrEMBL-Plants: tr|I1LDV2|I1LDV2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0304600 | 5 | ||
| – | TraB family protein; TAIR: AT5G52030.2 TraB family protein; Swiss-Prot: sp|Q9H4I3|TRABD_HUMAN TraB domain-containing protein; TrEMBL-Plants: tr|K7LL49|K7LL49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0304600 | 5 | ||
| – | TraB family protein; TAIR: AT5G52030.2 TraB family protein; Swiss-Prot: sp|Q9H4I3|TRABD_HUMAN TraB domain-containing protein; TrEMBL-Plants: tr|I1LDV2|I1LDV2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0304600 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd14726 | CDD | 1 | 8.33 |