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IPR003172

Source: InterPro

Description

IPR003172 is a MD-2-related lipid-recognition domain.

<p>The MD-2-related lipid-recognition (ML) domain is implicated in lipid recognition, particularly in the recognition of pathogen related products. It has an immunoglobulin-like β-sandwich fold similar to that of E-set Ig domains. This domain is present in proteins from plants, animals and fungi, including the following proteins: <ul> <li>Epididymal secretory protein E1 (also known as Niemann-Pick C2 protein -Npc2), which is known to bind cholesterol. Niemann-Pick disease type C2 is a fatal hereditary disease characterised by accumulation of low-density lipoprotein-derived cholesterol in lysosomes [[cite:PUB00029036]].</li> <li>House-dust mite allergen proteins such as Der f 2 from Dermatophagoides farinae and Der p 2 from Dermatophagoides pteronyssinus [[cite:PUB00032538]].</li> </ul> </p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 16

Transcript Name Description Predicted domains Domain count
Lj0g3v0190389.1
– PREDICTED: phosphatidylglycerol/phosphatidylinositol transfer protein-like [Glycine max] gi|356542064|ref|XP_003539491.1|
Domains
18
Lj2g3v2901270.1
– PREDICTED: phosphatidylglycerol/phosphatidylinositol transfer protein-like [Cicer arietinum] gi|502097992|ref|XP_004491129.1|
Domains
17
Lj2g3v2901270.2
– PREDICTED: phosphatidylglycerol/phosphatidylinositol transfer protein-like [Cicer arietinum] gi|502097992|ref|XP_004491129.1|
Domains
16
Lj3g3v1295720.1
– PREDICTED: phosphatidylglycerol/phosphatidylinositol transfer protein-like [Glycine max] gi|356542064|ref|XP_003539491.1|
Domains
18
Lj3g3v2927360.1
– PREDICTED: phosphatidylglycerol/phosphatidylinositol transfer protein-like [Cicer arietinum] gi|502145928|ref|XP_004506242.1|
Domains
16
Lj5g3v0841320.1
– Phosphatidylglycerol/phosphatidylinositol transfer protein precursor [Camellia sinensis] gi|330318646|gb|AEC10983.1|
Domains
16
LotjaGi1g1v0063300.1
– Phosphatidylglycerol/phosphatidylinositol transfer protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3SDT8|I3SDT8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0063300
Domains
16
LotjaGi1g1v0064600.1
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3T113|I3T113_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0064600
Domains
15
LotjaGi1g1v0064600.2
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3T113|I3T113_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0064600
Domains
16
LotjaGi1g1v0064600.3
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3T113|I3T113_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0064600
Domains
15
LotjaGi1g1v0064600.4
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.2 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3T113|I3T113_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0064600
Domains
16
LotjaGi1g1v0064700.1
– Phosphatidylglycerol/phosphatidylinositol transfer protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3SDT8|I3SDT8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0064700
Domains
17
LotjaGi3g1v0184400.1
– Phosphatidylglycerol/phosphatidylinositol transfer protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|C6TFA8|C6TFA8_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0184400
Domains
18
LotjaGi3g1v0470600.1
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G44100.1 MD-2-related lipid recognition domain-containing protein; Swiss-Prot: sp|D4AYQ6|NPC2_ARTBC Phosphatidylglycerol/phosphatidylinositol transfer protein; TrEMBL-Plants: tr|I3SA64|I3SA64_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0470600
Domains
18
LotjaGi5g1v0107000.1
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3T0S6|I3T0S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0107000
Domains
18
LotjaGi5g1v0107000.2
– MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; TAIR: AT3G11780.1 MD-2-related lipid recognition domain-containing protein / ML domain-containing protein; Swiss-Prot: sp|Q54SW1|Y2179_DICDI Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179; TrEMBL-Plants: tr|I3SG86|I3SG86_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0107000
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00917 CDD 1 6.25