Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR003175

Description

IPR003175 is a Cyclin-dependent kinase inhibitor domain.

<p>Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase. This entry represents a domain found in CDIs [[cite:PUB00019281]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Cyclin-dependent protein serine/threonine kinase inhibitor activity Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
Cellular component Nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Biological process Cell cycle arrest A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).

Associated Lotus transcripts 14

Transcript Name Description Predicted domains Domain count
PREDICTED: cyclin-dependent kinase inhibitor 7-like [Cicer arietinum] gi|502152913|ref|XP_004509150.1| 8
PREDICTED: cyclin-dependent kinase inhibitor 3-like [Cicer arietinum] gi|502103520|ref|XP_004492301.1| 7
PREDICTED: cyclin-dependent kinase inhibitor 3-like [Glycine max] gi|356576434|ref|XP_003556336.1| 6
PREDICTED: cyclin-dependent kinase inhibitor 3-like [Glycine max] gi|356576434|ref|XP_003556336.1| 6
PREDICTED: cyclin-dependent kinase inhibitor 3-like [Cicer arietinum] gi|502103520|ref|XP_004492301.1| 12
PREDICTED: cyclin-dependent kinase inhibitor 7-like [Cicer arietinum] gi|502160876|ref|XP_004511939.1| 8
PREDICTED: cyclin-dependent kinase inhibitor 7-like [Cucumis sativus] gi|449438418|ref|XP_004136985.1| 7
Cyclin-dependent kinase inhibitor family protein; TAIR: AT5G48820.1 inhibitor/interactor with cyclin-dependent kinase; Swiss-Prot: sp|Q9FKB5|KRP3_ARATH Cyclin-dependent kinase inhibitor 3; TrEMBL-Plants: tr|G7L186|G7L186_MEDTR Cyclin-dependent kinase inhibitor family protein; Found in the gene: LotjaGi1g1v0586500_LC 9
Cyclin dependent kinase inhibitor; TAIR: AT1G49620.1 Cyclin-dependent kinase inhibitor family protein; Swiss-Prot: sp|Q94CL9|KRP7_ARATH Cyclin-dependent kinase inhibitor 7; TrEMBL-Plants: tr|Q9FS28|Q9FS28_PEA Cyclin dependent kinase inhibitor; Found in the gene: LotjaGi2g1v0400200 7
Cyclin-dependent kinase inhibitor family protein; TAIR: AT1G49620.1 Cyclin-dependent kinase inhibitor family protein; Swiss-Prot: sp|Q94CL9|KRP7_ARATH Cyclin-dependent kinase inhibitor 7; TrEMBL-Plants: tr|V7CEB0|V7CEB0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0072700 6
Cyclin dependent kinase inhibitor; TAIR: AT1G49620.3 Cyclin-dependent kinase inhibitor family protein; Swiss-Prot: sp|Q94CL9|KRP7_ARATH Cyclin-dependent kinase inhibitor 7; TrEMBL-Plants: tr|I3SDJ1|I3SDJ1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0106100 8
Cyclin-dependent kinase inhibitor family protein; TAIR: AT5G48820.1 inhibitor/interactor with cyclin-dependent kinase; Swiss-Prot: sp|Q9FKB5|KRP3_ARATH Cyclin-dependent kinase inhibitor 3; TrEMBL-Plants: tr|G7L186|G7L186_MEDTR Cyclin-dependent kinase inhibitor family protein; Found in the gene: LotjaGi4g1v0121300 7
Cyclin-dependent kinase inhibitor; TAIR: AT5G48820.1 inhibitor/interactor with cyclin-dependent kinase; Swiss-Prot: sp|Q9FKB5|KRP3_ARATH Cyclin-dependent kinase inhibitor 3; TrEMBL-Plants: tr|A0A0L9VBM2|A0A0L9VBM2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0161800 7
Cyclin-dependent kinase inhibitor; TAIR: AT5G48820.1 inhibitor/interactor with cyclin-dependent kinase; Swiss-Prot: sp|Q9FKB5|KRP3_ARATH Cyclin-dependent kinase inhibitor 3; TrEMBL-Plants: tr|A0A0L9VBM2|A0A0L9VBM2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0161800 7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 7.14