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IPR004424 is a 4-diphosphocytidyl-2C-methyl-D-erythritol kinase.
<p>4-diphosphocytidyl-2C-methyl-D-erythritol kinase is a member of the family of GHMP kinases that were previously designated as conserved hypothetical protein YchB or as isopentenyl monophosphate kinase. In Solanum lycopersicum (Tomato) (Lycopersicon esculentum) and Escherichia coli the protein has been indentified as 4-diphosphocytidyl-2C-methyl-D-erythritol kinase, an enzyme of the deoxyxylulose phosphate pathway of terpenoid biosynthesis [[cite:PUB00015929]]. This enzyme is involved in the non-mevalonate pathway for isoprenoid biosynthesis [[cite:PUB00015669]] and in it is essential for for chloroplast development [[cite:PUB00095232]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Terpenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. | ||
| Molecular function | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity | Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic-like [Cicer arietinum] gi|502126787|ref|XP_004499437.1| | 14 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P93841|ISPE_SOLLC 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00154 | TIGRFAM | 1 | 25.00 |