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IPR013750 is a GHMP kinase, C-terminal domain.
<p>This domain is found in homoserine kinases ([ec:2.7.1.39]), galactokinases ([ec:2.7.1.6]) and mevalonate kinases ([ec:2.7.1.36]). These kinases make up the GHMP kinase superfamily of ATP-dependent enzymes [[cite:PUB00015675]]. These enzymes are involved in the biosynthesis of isoprenes and amino acids as well as in carbohydrate metabolism. The C-terminal domain of homoserine kinase has a central α-β plait fold and an insertion of four helices, which, together with the N-terminal fold, create a novel nucleotide binding fold [[cite:PUB00015644]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: L-arabinokinase-like [Cicer arietinum] gi|502124500|ref|XP_004498554.1| | 13 | ||
| – | PREDICTED: L-arabinokinase-like [Cicer arietinum] gi|502124500|ref|XP_004498554.1| | 20 | ||
| – | PREDICTED: galactokinase-like [Glycine max] gi|356565073|ref|XP_003550769.1| | 24 | ||
| – | PREDICTED: probable phosphomevalonate kinase-like [Cicer arietinum] gi|502136293|ref|XP_004502634.1| | 13 | ||
| – | Phosphomevalonate kinase [Medicago truncatula] gi|357463877|ref|XP_003602220.1| | 3 | ||
| – | PREDICTED: mevalonate kinase-like [Glycine max] gi|356505870|ref|XP_003521712.1| | 18 | ||
| – | PREDICTED: bifunctional fucokinase/fucose pyrophosphorylase-like [Cicer arietinum] gi|502114036|ref|XP_004494840.1| | 16 | ||
| – | PREDICTED: bifunctional fucokinase/fucose pyrophosphorylase-like [Cicer arietinum] gi|502114036|ref|XP_004494840.1| | 5 | ||
| – | PREDICTED: glucuronokinase 1-like [Cicer arietinum] gi|502090342|ref|XP_004489197.1| | 14 | ||
| – | Homoserine kinase-like [Glycine max] gi|359807161|ref|NP_001241610.1| | 18 | ||
| – | PREDICTED: galactokinase-like [Cicer arietinum] gi|502150796|ref|XP_004508128.1| | 24 | ||
| – | Galactokinase [Medicago truncatula] gi|357520677|ref|XP_003630627.1| | 18 | ||
| – | PREDICTED: diphosphomevalonate decarboxylase-like [Cicer arietinum] gi|502121015|ref|XP_004497159.1| | 15 | ||
| – | PREDICTED: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic-like [Cicer arietinum] gi|502126787|ref|XP_004499437.1| | 14 | ||
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A1J7GGC5|A0A1J7GGC5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0283600 | 8 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600 | 12 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Glucuronokinase 1; TAIR: AT3G01640.2 glucuronokinase G; Swiss-Prot: sp|Q93ZC9|GLAK1_ARATH Glucuronokinase 1; TrEMBL-Plants: tr|I3S7C0|I3S7C0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0239500 | 12 | ||
| – | Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0332900 | 26 | ||
| – | Galactokinase; TAIR: AT3G10700.1 galacturonic acid kinase; Swiss-Prot: sp|Q8VYG2|GALAK_ARATH Galacturonokinase; TrEMBL-Plants: tr|G7LJJ0|G7LJJ0_MEDTR Galactokinase; Found in the gene: LotjaGi4g1v0440500 | 19 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P93841|ISPE_SOLLC 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 16 | ||
| – | Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0260600 | 26 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00131 | TIGRFAM | 1 | 2.78 |