Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR006204

Source: InterPro

Description

IPR006204 is a GHMP kinase N-terminal domain.

<p>The galacto- ([ec:2.7.1.6]), homoserine ([ec:2.7.1.39]), mevalonate ([ec:2.7.1.36]) and phosphomevalonate ([ec:2.7.4.2]) kinases contain, in their N-terminal section, a conserved domain with a Gly/Ser-rich region which is probably involved in the binding of ATP [[cite:PUB00003676], [cite:PUB00006508]]. This group of kinases has been called 'GHMP' (from the first letter of their substrates).</p> <p>This domain is also found in diphosphomevalonate decarboxylases, which are structurally related members of the GHMP superfamily [[cite:PUB00041428]], but do not possess kinase activity.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005524
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Subterm of

Associated Lotus transcripts 40

Transcript Name Description Predicted domains Domain count
Lj0g3v0335759.1
– PREDICTED: L-arabinokinase-like [Cicer arietinum] gi|502124500|ref|XP_004498554.1|
Domains
13
Lj0g3v0335759.2
– PREDICTED: L-arabinokinase-like [Cicer arietinum] gi|502124500|ref|XP_004498554.1|
Domains
20
Lj0g3v0357339.1
– PREDICTED: galactokinase-like [Glycine max] gi|356565073|ref|XP_003550769.1|
Domains
24
Lj1g3v0968900.1
– PREDICTED: probable phosphomevalonate kinase-like [Cicer arietinum] gi|502136293|ref|XP_004502634.1|
Domains
13
Lj1g3v4942840.1
– PREDICTED: mevalonate kinase-like [Glycine max] gi|356505870|ref|XP_003521712.1|
Domains
13
Lj1g3v4943880.1
– PREDICTED: mevalonate kinase-like [Glycine max] gi|356505870|ref|XP_003521712.1|
Domains
18
Lj1g3v5038190.1
– PREDICTED: bifunctional fucokinase/fucose pyrophosphorylase-like [Cicer arietinum] gi|502114036|ref|XP_004494840.1|
Domains
16
Lj2g3v0920490.1
– PREDICTED: glucuronokinase 1-like [Cicer arietinum] gi|502090342|ref|XP_004489197.1|
Domains
14
Lj2g3v3413250.1
– Homoserine kinase-like [Glycine max] gi|359807161|ref|NP_001241610.1|
Domains
18
Lj4g3v2263880.1
– PREDICTED: galactokinase-like [Cicer arietinum] gi|502150796|ref|XP_004508128.1|
Domains
24
Lj4g3v3015190.1
– Galactokinase [Medicago truncatula] gi|357520677|ref|XP_003630627.1|
Domains
18
Lj5g3v2240960.1
– PREDICTED: diphosphomevalonate decarboxylase-like [Cicer arietinum] gi|502121015|ref|XP_004497159.1|
Domains
15
Lj6g3v1008180.1
– PREDICTED: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic-like [Cicer arietinum] gi|502126787|ref|XP_004499437.1|
Domains
14
LotjaGi1g1v0000900.1
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi1g1v0000900.2
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi1g1v0000900.3
– Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900
Domains
19
LotjaGi1g1v0283600.1
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0283600.3
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0283600.4
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0283600.5
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0283600.6
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0283600.7
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A075EBV2|A0A075EBV2_ASTME Phosphomevalonate kinase 1; Found in the gene: LotjaGi1g1v0283600
Domains
12
LotjaGi1g1v0286000_LC.1
– Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|C6T7N7|C6T7N7_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0286000_LC
Domains
15
LotjaGi1g1v0293300.2
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|A0A151TY35|A0A151TY35_CAJCA L-fucose kinase; Found in the gene: LotjaGi1g1v0293300
Domains
8
LotjaGi1g1v0293300.3
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|A0A151TY35|A0A151TY35_CAJCA L-fucose kinase; Found in the gene: LotjaGi1g1v0293300
Domains
8
LotjaGi1g1v0293300.4
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|A0A151TY35|A0A151TY35_CAJCA L-fucose kinase; Found in the gene: LotjaGi1g1v0293300
Domains
8
LotjaGi1g1v0794600.1
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600
Domains
15
LotjaGi1g1v0794600.2
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600
Domains
15
LotjaGi1g1v0794600.3
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600
Domains
15
LotjaGi1g1v0794600.4
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600
Domains
15
LotjaGi1g1v0794600.5
– Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600
Domains
15
LotjaGi2g1v0239500.1
– Glucuronokinase 1; TAIR: AT3G01640.2 glucuronokinase G; Swiss-Prot: sp|Q93ZC9|GLAK1_ARATH Glucuronokinase 1; TrEMBL-Plants: tr|I3S7C0|I3S7C0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0239500
Domains
12
LotjaGi4g1v0332900.1
– Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0332900
Domains
26
LotjaGi4g1v0440500.1
– Galactokinase; TAIR: AT3G10700.1 galacturonic acid kinase; Swiss-Prot: sp|Q8VYG2|GALAK_ARATH Galacturonokinase; TrEMBL-Plants: tr|G7LJJ0|G7LJJ0_MEDTR Galactokinase; Found in the gene: LotjaGi4g1v0440500
Domains
19
LotjaGi5g1v0126900.1
– Galactokinase; TAIR: AT4G16130.1 arabinose kinase; Swiss-Prot: sp|O23461|ARAK_ARATH L-arabinokinase; TrEMBL-Plants: tr|A0A151SH14|A0A151SH14_CAJCA Galactokinase; Found in the gene: LotjaGi5g1v0126900
Domains
20
LotjaGi5g1v0345200.2
– Diphosphomevalonate decarboxylase; TAIR: AT3G54250.1 GHMP kinase family protein; Swiss-Prot: sp|F4JCU3|MVD2_ARATH Diphosphomevalonate decarboxylase MVD2, peroxisomal; TrEMBL-Plants: tr|A0A1J7IDM5|A0A1J7IDM5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0345200
Domains
17
LotjaGi6g1v0187700.1
– 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700
Domains
15
LotjaGi6g1v0187700.2
– 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700
Domains
15
LotjaGi6g1v0187700.3
– 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P93841|ISPE_SOLLC 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700
Domains
16
LotjaGi6g1v0260600.1
– Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0260600
Domains
26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00131 TIGRFAM 1 2.50