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IPR036554 is a GHMP kinase, C-terminal domain superfamily.
<p>This domain superfamily is found in homoserine kinases ([ec:2.7.1.39]), galactokinases ([ec:2.7.1.6]) and mevalonate kinases ([ec:2.7.1.36]). These kinases make up the GHMP kinase superfamily of ATP-dependent enzymes [[cite:PUB00015675], [cite:PUB00049240]]. These enzymes are involved in the biosynthesis of isoprenes and amino acids as well as in carbohydrate metabolism. The C-terminal domain of homoserine kinase has a central α-β plait fold and an insertion of four helices, which, together with the N-terminal fold, create a novel nucleotide binding fold [[cite:PUB00015644]].</p> <p>This domain superfamily is also found in some diphosphomevalonate decarboxylases, which are structurally related members of the GHMP superfamily [[cite:PUB00041428]], but do not possess kinase activity.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Homoserine kinase; TAIR: AT2G17265.1 homoserine kinase; Swiss-Prot: sp|Q8L7R2|KHSE_ARATH Homoserine kinase; TrEMBL-Plants: tr|D2DKF1|D2DKF1_SOYBN Homoserine kinase; Found in the gene: LotjaGi1g1v0000900 | 19 | ||
| – | Phosphomevalonate kinase; TAIR: AT1G31910.1 GHMP kinase family protein; Swiss-Prot: sp|Q9C6T1|PMK_ARATH Phosphomevalonate kinase, peroxisomal; TrEMBL-Plants: tr|A0A1J7GGC5|A0A1J7GGC5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0283600 | 8 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Bifunctional fucokinase/fucose pyrophosphorylase; TAIR: AT1G01220.1 L-fucokinase/GDP-L-fucose pyrophosphorylase; Swiss-Prot: sp|Q9LNJ9|FKGP_ARATH Bifunctional fucokinase/fucose pyrophosphorylase; TrEMBL-Plants: tr|G7L443|G7L443_MEDTR L-fucokinase/GDP-L-fucose pyrophosphorylase; Found in the gene: LotjaGi1g1v0794600 | 15 | ||
| – | Glucuronokinase 1; TAIR: AT3G01640.2 glucuronokinase G; Swiss-Prot: sp|Q93ZC9|GLAK1_ARATH Glucuronokinase 1; TrEMBL-Plants: tr|I3S7C0|I3S7C0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0239500 | 12 | ||
| – | Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0332900 | 26 | ||
| – | Galactokinase; TAIR: AT3G10700.1 galacturonic acid kinase; Swiss-Prot: sp|Q8VYG2|GALAK_ARATH Galacturonokinase; TrEMBL-Plants: tr|G7LJJ0|G7LJJ0_MEDTR Galactokinase; Found in the gene: LotjaGi4g1v0440500 | 19 | ||
| – | Galactokinase; TAIR: AT4G16130.1 arabinose kinase; Swiss-Prot: sp|O23461|ARAK_ARATH L-arabinokinase; TrEMBL-Plants: tr|A0A151SH14|A0A151SH14_CAJCA Galactokinase; Found in the gene: LotjaGi5g1v0126900 | 20 | ||
| – | Diphosphomevalonate decarboxylase; TAIR: AT3G54250.1 GHMP kinase family protein; Swiss-Prot: sp|F4JCU3|MVD2_ARATH Diphosphomevalonate decarboxylase MVD2, peroxisomal; TrEMBL-Plants: tr|A0A1J7IDM5|A0A1J7IDM5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0345200 | 17 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P56848|ISPE_MENPI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 15 | ||
| – | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TAIR: AT2G26930.1 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; Swiss-Prot: sp|P93841|ISPE_SOLLC 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic; TrEMBL-Plants: tr|I3T103|I3T103_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0187700 | 16 | ||
| – | Galactokinase; TAIR: AT3G06580.1 Mevalonate/galactokinase family protein; Swiss-Prot: sp|Q9SEE5|GALK1_ARATH Galactokinase; TrEMBL-Plants: tr|I1MRT3|I1MRT3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0260600 | 26 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00131 | TIGRFAM | 1 | 5.56 |