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IPR005067 is a Fatty acid desaturase, type 2.
<p>Fatty acid desaturases are enzymes that catalyse the insertion of a double bond at the delta position of fatty acids.</p> <p>There seem to be two distinct families of fatty acid desaturases which do not seem to be evolutionary related.</p> <p>Family 1 is composed of:</p> <ul> <li>Stearoyl-CoA desaturase (SCD) ([ec:1.14.19.1]) [[cite:PUB00002505]].</li> </ul> <p>Family 2 is composed of:</p> <ul> <li>Bacterial fatty acid desaturases.</li> <li>Plant stearoyl-acyl-carrier-protein desaturase ([ec:1.14.19.1]) [[cite:PUB00004734]], this enzyme catalyses the introduction of a double bond at the delta(9) position of steraoyl-ACP to produce oleoyl-ACP. This enzyme is responsible for the conversion of saturated fatty acids to unsaturated fatty acids in the synthesis of vegetable oils.</li> <li>Cyanobacterial DesA [[cite:PUB00004074]], an enzyme that can introduce a second cis double bond at the delta(12) position of fatty acid bound to membranes glycerolipids. DesA is involved in chilling tolerance; the phase transition temperature of lipids of cellular membranes being dependent on the degree of unsaturation of fatty acids of the membrane lipids.</li> </ul> <p>This entry contains fatty acid desaturases belonging to Family 2, also known as Acyl-ACP (Acyl Carrier Protein) desaturases.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Fatty acid metabolic process | The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. | ||
| Molecular function | Acyl-[acyl-carrier-protein] desaturase activity | Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Acyl-[acyl]-carrier-protein] gi|67633223|gb|AAY78547.1| | 16 | ||
| – | PREDICTED: acyl-[acyl]-carrier-protein] gi|502124091|ref|XP_004498381.1| | 11 | ||
| – | Acyl-[acyl]-carrier-protein] gi|67633223|gb|AAY78547.1| | 16 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT1G43800.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q84VY3|STAD6_ARATH Stearoyl-[acyl]-carrier-protein] 9-desaturase 6, chloroplastic; TrEMBL-Plants: tr|A0A072VEM1|A0A072VEM1_MEDTR Stearoyl-acyl-carrier desaturase; Found in the gene: LotjaGi1g1v0168700 | 11 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 | 17 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 | 12 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.2 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 | 12 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 | 18 | ||
| – | Acyl-[acyl]-carrier-protein] desaturase; TAIR: AT2G43710.1 Plant stearoyl-acyl-carrier-protein desaturase family protein; Swiss-Prot: sp|Q42807|STAD_SOYBN Stearoyl-[acyl]-carrier-protein] 9-desaturase, chloroplastic; TrEMBL-Plants: tr|Q4PZD4|Q4PZD4_LOTJA Acyl-[acyl]-carrier-protein] desaturase; Found in the gene: LotjaGi4g1v0068200 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01050 | CDD | 1 | 11.11 |