Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR006384

Description

IPR006384 is a HAD hydrolase, subfamily IA, Pyridoxal phosphate phosphatase-like.

<p>The Haloacid Dehalogenase (HAD) superfamily is defined by the presence of three short catalytic motifs [[cite:PUB00003337]]. The subfamilies are defined [[cite:PUB00009589]] based on the location and the observed or predicted fold of a so-called capping domain [[cite:PUB00009540]], or the absence of such a domain. Subfamily I consists of sequences in which the capping domain is found in between the first and second catalytic motifs. Subfamily II consists of sequences in which the capping domain is found between the second and third motifs. Subfamily III sequences have no capping domain in either of these positions.</p> <p>The Subfamily IA and IB capping domains are predicted by PSI-PRED to consist of an α helical bundle. Subfamily IA and IB are separated based on an apparent phylogenetic bifurcation. This group of sequences belong to the IB subfamily of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

Associated Lotus transcripts 13

Transcript Name Description Predicted domains Domain count
Pyridoxal phosphate phosphatase PHOSPHO2 [Medicago truncatula] gi|357520709|ref|XP_003630643.1| 12
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356526037|ref|XP_003531626.1| 12
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356526041|ref|XP_003531628.1| 13
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356526041|ref|XP_003531628.1| 12
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356526037|ref|XP_003531626.1| 12
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356522610|ref|XP_003529939.1| 13
PREDICTED: inorganic pyrophosphatase 2-like [Glycine max] gi|356526041|ref|XP_003531628.1| 12
Inorganic pyrophosphatase 2; TAIR: AT1G17710.1 Pyridoxal phosphate phosphatase-related protein; Swiss-Prot: sp|Q9FZ62|PPSP2_ARATH Inorganic pyrophosphatase 2; TrEMBL-Plants: tr|A0A0L9TA82|A0A0L9TA82_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0024000 12
Inorganic pyrophosphatase 2; TAIR: AT1G17710.1 Pyridoxal phosphate phosphatase-related protein; Swiss-Prot: sp|Q9FZ62|PPSP2_ARATH Inorganic pyrophosphatase 2; TrEMBL-Plants: tr|I3T6F3|I3T6F3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0024100 12
Inorganic pyrophosphatase 2; TAIR: AT1G17710.1 Pyridoxal phosphate phosphatase-related protein; Swiss-Prot: sp|Q9FZ62|PPSP2_ARATH Inorganic pyrophosphatase 2; TrEMBL-Plants: tr|I3S8Y2|I3S8Y2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0426600 12
Inorganic pyrophosphatase 2; TAIR: AT1G17710.1 Pyridoxal phosphate phosphatase-related protein; Swiss-Prot: sp|Q9FZ62|PPSP2_ARATH Inorganic pyrophosphatase 2; TrEMBL-Plants: tr|I3S8Y2|I3S8Y2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0426700 12
Inorganic pyrophosphatase 2; TAIR: AT1G73010.1 inorganic pyrophosphatase 1; Swiss-Prot: sp|Q67YC0|PPSP1_ARATH Inorganic pyrophosphatase 1; TrEMBL-Plants: tr|I3S8Y2|I3S8Y2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0426800 12
Inorganic pyrophosphatase 2; TAIR: AT1G17710.1 Pyridoxal phosphate phosphatase-related protein; Swiss-Prot: sp|Q9FZ62|PPSP2_ARATH Inorganic pyrophosphatase 2; TrEMBL-Plants: tr|G7LJK6|G7LJK6_MEDTR 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Found in the gene: LotjaGi4g1v0441200 12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR01489 TIGRFAM 1 7.69