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IPR006449 is a Squalene synthase-like.
<p>This family of sequences describe farnesyl-diphosphate farnesyltransferase, also known as squalene synthase, as found in eukaryotes. This family is related to phytoene synthases. Tentatively identified archaeal homologues lack the C-terminal predicted transmembrane region universally conserved among members of this family and therefore are not included in this group.</p> <p>This family also includes squalene synthase-like (SSL) proteins from green algae. SSL-3 (Botryococcene synthase) produces botryococcene when coexpressed with SSL-1 (Presqualene diphosphate synthase). SSL-3 has no activity with farnesyl diphosphate as substrate [[cite:PUB00086654]]. SSL-2 (Botryococcus squalene synthase) produces squalene when coexpressed with SSL-1 and bisfarnesyl ether [[cite:PUB00086654]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Lipid biosynthetic process | The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. | ||
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Squalene synthase [Lotus japonicus] gi|28208268|dbj|BAC56854.1| | 18 | ||
| – | Squalene synthase [Lotus japonicus] gi|28208268|dbj|BAC56854.1| | 18 | ||
| – | Squalene synthase; TAIR: AT4G34640.1 squalene synthase 1; Swiss-Prot: sp|P53800|FDFT_NICBE Squalene synthase; TrEMBL-Plants: tr|Q84LE3|Q84LE3_LOTJA Squalene synthase; Found in the gene: LotjaGi3g1v0513800 | 20 | ||
| – | Squalene synthase; TAIR: AT4G34640.1 squalene synthase 1; Swiss-Prot: sp|P53800|FDFT_NICBE Squalene synthase; TrEMBL-Plants: tr|Q84LE3|Q84LE3_LOTJA Squalene synthase; Found in the gene: LotjaGi3g1v0513800 | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00683 | CDD | 1 | 25.00 |