Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR006691

Source: InterPro

Description

IPR006691 is a DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat.

<p>This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 β strands and to probably form a β-propeller structure [[cite:PUB00009362]]. This region has been shown to bind DNA non-specifically and may stabilise the DNA-topoisomerase complex [[cite:PUB00008991]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003677
Molecular function DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Subterm of
GO:0003916
Molecular function DNA topoisomerase activity Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
Subterm of
GO:0005524
Molecular function ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
Subterm of
GO:0006265
Biological process DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
Subterm of

Associated Lotus transcripts 5

Transcript Name Description Predicted domains Domain count
Lj2g3v0146560.1
– PREDICTED: DNA gyrase subunit A, chloroplastic/mitochondrial-like isoform X1 [Cicer arietinum] gi|502127538|ref|XP_004499748.1|
Domains
18
LotjaGi2g1v0064900.1
– DNA gyrase subunit A; TAIR: AT3G10690.1 DNA GYRASE A; Swiss-Prot: sp|Q5YLB5|GYRA_NICBE DNA gyrase subunit A, chloroplastic/mitochondrial; TrEMBL-Plants: tr|G7I9Z9|G7I9Z9_MEDTR DNA gyrase subunit A; Found in the gene: LotjaGi2g1v0064900
Domains
22
LotjaGi2g1v0064900.2
– DNA gyrase subunit A; TAIR: AT3G10690.1 DNA GYRASE A; Swiss-Prot: sp|Q5YLB5|GYRA_NICBE DNA gyrase subunit A, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1L2U5|I1L2U5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0064900
Domains
20
LotjaGi2g1v0064900.3
– DNA gyrase subunit A; TAIR: AT3G10690.1 DNA GYRASE A; Swiss-Prot: sp|Q5YLB5|GYRA_NICBE DNA gyrase subunit A, chloroplastic/mitochondrial; TrEMBL-Plants: tr|G7I9Z9|G7I9Z9_MEDTR DNA gyrase subunit A; Found in the gene: LotjaGi2g1v0064900
Domains
20
LotjaGi2g1v0064900.4
– DNA gyrase subunit A; TAIR: AT3G10690.1 DNA GYRASE A; Swiss-Prot: sp|Q5YLB5|GYRA_NICBE DNA gyrase subunit A, chloroplastic/mitochondrial; TrEMBL-Plants: tr|G7I9Z9|G7I9Z9_MEDTR DNA gyrase subunit A; Found in the gene: LotjaGi2g1v0064900
Domains
19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 20.00