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IPR006963

Description

IPR006963 is a Molybdopterin oxidoreductase, 4Fe-4S domain.

<p>The molybdopterin oxidoreductase 4Fe-4S domain is found in a number of reductase/dehydrogenase families, which include the periplasmic nitrate reductase precursor and the formate dehydrogenase alpha chain [[cite:PUB00009739]].</p> <p>The following proteins contain this domain and belong to the molybdenium (Mo) or tungsten (W) containing enzyme family, the Mo/W bis-MGD (molybdopterin-guanine-dinucleotide) oxydoreductases [[cite:PUB00000608], [cite:PUB00003788], [cite:PUB00002890]]:</p> <ul> <li>Escherichia coli respiratory nitrate reductase ([ec:1.7.99.4]).</li> <li>Escherichia coli anaerobic dimethyl sulfoxide reductase (DMSO reductase).</li> <li>Escherichia coli biotin sulfoxide reductases (genes bisC and bisZ).</li> <li>Methanobacterium formicicum formate dehydrogenase ([ec:1.2.1.2]).</li> <li>Escherichia coli formate dehydrogenases -H (gene fdhF), -N (gene fdnG) and -O (gene fdoG).</li> <li>Wolinella succinogenes polysulfide reductase chain.</li> <li>Salmonella typhimurium thiosulfate reductase (gene phsA).</li> <li>Escherichia coli trimethylamine-N-oxide reductase ([ec:1.6.6.9]) (gene torA) [[cite:PUB00003854]].</li> <li>Nitrate reductase ([ec:1.7.99.4]) from Klebsiella pneumoniae (gene nasA), Alcaligenes eutrophus, Escherichia coli, Rhodobacter sphaeroides, Thiosphaera pantotropha (gene napA), and Synechococcus PCC 7942 (gene narB).</li></ul>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
PREDICTED: NADH dehydrogenase [ubiquinone] gi|356539814|ref|XP_003538388.1| 29
NADH-ubiquinone oxidoreductase subunit; TAIR: AT5G37510.1 NADH-ubiquinone dehydrogenase; Swiss-Prot: sp|Q43644|NDUS1_SOLTU NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial; TrEMBL-Plants: tr|A0A0S3RZR3|A0A0S3RZR3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0054900 31

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00