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IPR010158

Source: InterPro

Description

IPR010158 is a Amidase, carbamoylase-type.

<p>L-carbamoylases (N-carbamoyl-L-amino-acid amidohydrolases) hydrolyze the amide bond of the carbamoyl group in L-N-carbamoyl-amino acids [[cite:PUB00028029]]. They are important industrial enzymes widely used for the production of optically pure amino acids due to their stereospecificity. Furthermore, their substrate promiscuity allows their use in different multienzymatic processes [[cite:PUB00079871], [cite:PUB00079879]].</p> <p>Also included in this family is allantoate amidohydrolase (allantoate deiminase), which catalyzes the conversion of allantoate to (S)-ureidoglycolate, one of the crucial alternate steps in purine metabolism [[cite:PUB00041739]], and yeast N-carbamyl-beta-alanine amidohydrolase (betaAS, beta-alanine synthase) [[cite:PUB00049624], [cite:PUB00030509]].</p> <p>These enzymes are members of the broader family of amidases.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016813
Molecular function Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
Subterm of

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
Lj5g3v1174280.1
– PREDICTED: N-carbamoyl-L-amino acid hydrolase-like [Cicer arietinum] gi|502116230|ref|XP_004495345.1|
Domains
21
Lj6g3v1392530.1
– PREDICTED: allantoate deiminase, chloroplastic-like [Glycine max] gi|356530191|ref|XP_003533667.1|
Domains
23
Lj6g3v1413760.1
– Allantoate amidohydrolase [Glycine max] gi|218158555|gb|ACK75561.1|
Domains
16
LotjaGi5g1v0186900.1
– N-carbamyl-L-amino acid amidohydrolase; TAIR: AT5G43600.1 ureidoglycolate amidohydrolase; Swiss-Prot: sp|Q8VXY9|UAH_ARATH Ureidoglycolate hydrolase; TrEMBL-Plants: tr|G7I3Z0|G7I3Z0_MEDTR N-carbamyl-L-amino acid amidohydrolase; Found in the gene: LotjaGi5g1v0186900
Domains
20
LotjaGi5g1v0186900.2
– N-carbamyl-L-amino acid amidohydrolase; TAIR: AT5G43600.1 ureidoglycolate amidohydrolase; Swiss-Prot: sp|Q8VXY9|UAH_ARATH Ureidoglycolate hydrolase; TrEMBL-Plants: tr|G7I3Z0|G7I3Z0_MEDTR N-carbamyl-L-amino acid amidohydrolase; Found in the gene: LotjaGi5g1v0186900
Domains
20
LotjaGi6g1v0244500.1
– Allantoate amidohydrolase; TAIR: AT4G20070.1 allantoate amidohydrolase; Swiss-Prot: sp|O49434|AAH_ARATH Allantoate deiminase; TrEMBL-Plants: tr|I3SAX9|I3SAX9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0244500
Domains
17
LotjaGi6g1v0244500.2
– Allantoate amidohydrolase; TAIR: AT4G20070.1 allantoate amidohydrolase; Swiss-Prot: sp|O49434|AAH_ARATH Allantoate deiminase; TrEMBL-Plants: tr|I1L153|I1L153_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0244500
Domains
22
LotjaGi6g1v0244500.3
– Allantoate amidohydrolase; TAIR: AT4G20070.1 allantoate amidohydrolase; Swiss-Prot: sp|O49434|AAH_ARATH Allantoate deiminase; TrEMBL-Plants: tr|I3SAX9|I3SAX9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0244500
Domains
17
LotjaGi6g1v0244500.4
– Allantoate amidohydrolase; TAIR: AT4G20070.1 allantoate amidohydrolase; Swiss-Prot: sp|O49434|AAH_ARATH Allantoate deiminase; TrEMBL-Plants: tr|I3SAX9|I3SAX9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0244500
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03884 CDD 1 11.11