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IPR016084 is a Haem oxygenase-like, multi-helical.
<p>This superfamily represents a multi-helical structural domain consisting of two structural repeats (duplication) of a 3-helical motif. This domain can be found in both eukaryotic and prokaryotic haem oxygenases [[cite:PUB00022669], [cite:PUB00026272]], in TENA/THI-4 proteins that lack the haem-binding site [[cite:PUB00030800]], and in coenzyme PQQ (pyrrolo-quinoline-quinone) biosynthesis protein C (PqqC) [[cite:PUB00029597]].</p> <p>Haem oxygenase ([ec:1.14.99.3]) (HO) is the microsomal enzyme that, in animals, carries out the oxidation of haem, cleaving the haem ring at the alpha-methene bridge to form biliverdin and carbon monoxide. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. In mammals there are three isozymes of haem oxygenase: HO-1 to HO-3. The first two isozymes differ in their tissue expression and their inducibility: HO-1 is highly inducible by its substrate haem and by various non-haem substances, while HO-2 is non-inducible. Haem oxygenase is also present in certain bacteria, where it is involved in the acquisition of iron from the host haem.</p> <p>The THI-4 protein is involved in thiamine biosynthesis, while TENA is one of a number of proteins that enhance the expression of extracellular enzymes, such as alkaline protease, neutral protease and levansucrase.</p> <p>Coenzyme PQQ (pyrrolo-quinoline-quinone) biosynthesis protein C (PqqC; [ec:1.3.3.11]) is required for the synthesis of PQQ, where PQQ is a prosthetic group found in several bacterial enzymes, including methanol dehydrogenase of methylotrophs and the glucose dehydrogenase of a number of bacteria.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Chromoplast heme oxygenase 1 [Medicago sativa] gi|300431417|gb|ADK12637.1| | 10 | ||
| – | Seed maturation protein PM36 [Medicago truncatula] gi|357478951|ref|XP_003609761.1| | 9 | ||
| – | Heme oxygenase-like, multi-helical isoform 1 [Theobroma cacao] gi|508718932|gb|EOY10829.1| | 10 | ||
| – | Heme oxygenase 1; TAIR: AT2G26670.1 Plant heme oxygenase (decyclizing) family protein; Swiss-Prot: sp|O48782|HMOX1_ARATH Heme oxygenase 1, chloroplastic; TrEMBL-Plants: tr|I3SL57|I3SL57_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0199700 | 10 | ||
| – | Heme oxygenase 1; TAIR: AT2G26670.1 Plant heme oxygenase (decyclizing) family protein; Swiss-Prot: sp|O48782|HMOX1_ARATH Heme oxygenase 1, chloroplastic; TrEMBL-Plants: tr|I3SL57|I3SL57_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0199700 | 10 | ||
| – | Seed maturation PM36-like protein; TAIR: AT3G16990.1 heme oxygenase-like, multi-helical; Swiss-Prot: sp|Q9SWB6|TENAE_SOYBN Probable bifunctional TENA-E protein; TrEMBL-Plants: tr|G7JMU3|G7JMU3_MEDTR Seed maturation PM36-like protein; Found in the gene: LotjaGi4g1v0330100 | 9 | ||
| – | Heme oxygenase; TAIR: AT2G26550.2 heme oxygenase 2; Swiss-Prot: sp|O48722|HMOX2_ARATH Probable inactive heme oxygenase 2, chloroplastic; TrEMBL-Plants: tr|A0A0B2SHY8|A0A0B2SHY8_GLYSO Putative inactive heme oxygenase 2, chloroplastic; Found in the gene: LotjaGi5g1v0025400 | 8 | ||
| – | Heme oxygenase-like, multi-helical protein; TAIR: AT5G32470.1 heme oxygenase-like, multi-helical; Swiss-Prot: sp|F4KFT7|TENAC_ARATH Bifunctional TH2 protein, mitochondrial; TrEMBL-Plants: tr|K7N529|K7N529_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0210500 | 12 | ||
| – | Heme oxygenase-like, multi-helical protein; TAIR: AT5G32470.1 heme oxygenase-like, multi-helical; Swiss-Prot: sp|F4KFT7|TENAC_ARATH Bifunctional TH2 protein, mitochondrial; TrEMBL-Plants: tr|K7N529|K7N529_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0210500 | 11 | ||
| – | Heme oxygenase-like, multi-helical protein; TAIR: AT5G32470.1 heme oxygenase-like, multi-helical; Swiss-Prot: sp|F4KFT7|TENAC_ARATH Bifunctional TH2 protein, mitochondrial; TrEMBL-Plants: tr|K7N529|K7N529_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0210500 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF56784 | SUPERFAMILY | 1 | 10.00 |