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IPR018110

Source: InterPro

Description

IPR018110 is a Mandelate racemase/muconate lactonizing enzyme, conserved site.

<p>Mandelate racemase [ec:5.1.2.2] (MR) and muconate lactonizing enzyme [ec:5.5.1.1] (MLE) are two bacterial enzymes involved in aromatic acid catabolism. They catalyse mechanistically distinct reactions, yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures [[cite:PUB00004081], [cite:PUB00005404]]. A number of other proteins also seem to be evolutionary related to these two enzymes. These include various plasmid-encoded chloromuconate cycloisomerases [ec:5.5.1.7], Escherichia coli protein rspA [[cite:PUB00005187]], E. coli bifunctional DGOA protein, E. coli hypothetical proteins ycjG, yfaW and yidU, and a hypothetical protein from Streptomyces ambofaciens [[cite:PUB00003121]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0009063
Biological process Cellular amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj3g3v3654520.1
– PREDICTED: protein PHYLLO, chloroplastic-like [Cicer arietinum] gi|502154072|ref|XP_004509573.1|
Domains
19
LotjaGi4g1v0153600.1
– 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; TAIR: AT1G68890.1 2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding protein; Swiss-Prot: sp|Q15KI9|PHYLO_ARATH Protein PHYLLO, chloroplastic; TrEMBL-Plants: tr|K7MEA2|K7MEA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0153600
Domains
38

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd07037 CDD 1 50.00