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PF02775

Source: Pfam

Description

Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003824
Molecular function Catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Subterm of
GO:0030976
Molecular function Thiamine pyrophosphate binding Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Subterm of

Associated Lotus transcripts 18

Transcript Name Description Predicted domains Domain count
Lj0g3v0332289.1
– Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Theobroma cacao] gi|508715239|gb|EOY07136.1|
Domains
19
Lj1g3v1513620.1
– Acetolactate synthase [Medicago littoralis] gi|164453114|gb|ABY57316.1|
Domains
20
Lj1g3v2372300.1
– Pyruvate decarboxylase 1 [Lotus corniculatus] gi|29373077|gb|AAO72533.1|
Domains
18
Lj2g3v0919440.1
– PREDICTED: 2-hydroxyacyl-CoA lyase-like [Glycine max] gi|356553206|ref|XP_003544949.1|
Domains
19
Lj6g3v1995950.1
– Pyruvate decarboxylase isozyme 1 [Lotus japonicus] gi|51587336|emb|CAG30578.1|
Domains
18
Lj6g3v1995960.1
–
Domains
18
Lj6g3v2043240.1
– PREDICTED: acetolactate synthase 1, chloroplastic-like [Cicer arietinum] gi|502077817|ref|XP_004485753.1|
Domains
20
LotjaGi1g1v0338500.1
– Acetolactate synthase; TAIR: AT3G48560.1 chlorsulfuron/imidazolinone resistant 1; Swiss-Prot: sp|P09114|ILVB2_TOBAC Acetolactate synthase 2, chloroplastic; TrEMBL-Plants: tr|B0FBK4|B0FBK4_9FABA Acetolactate synthase; Found in the gene: LotjaGi1g1v0338500
Domains
21
LotjaGi1g1v0443800.1
– Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800
Domains
18
LotjaGi1g1v0443800.2
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|P51851|PDC2_PEA Pyruvate decarboxylase 2; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800
Domains
13
LotjaGi1g1v0443800.3
– Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800
Domains
18
LotjaGi2g1v0238100.1
– Acetolactate synthase; TAIR: AT5G17380.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|Q9LF46|HACL_ARATH 2-hydroxyacyl-CoA lyase; TrEMBL-Plants: tr|A0A151TX24|A0A151TX24_CAJCA 2-hydroxyacyl-CoA lyase 1; Found in the gene: LotjaGi2g1v0238100
Domains
19
LotjaGi3g1v0195000.1
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi3g1v0195000.2
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi3g1v0195000.3
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000
Domains
19
LotjaGi4g1v0153600.1
– 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; TAIR: AT1G68890.1 2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding protein; Swiss-Prot: sp|Q15KI9|PHYLO_ARATH Protein PHYLLO, chloroplastic; TrEMBL-Plants: tr|K7MEA2|K7MEA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0153600
Domains
38
LotjaGi6g1v0324800.1
– Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|P51850|PDC1_PEA Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q684K0|Q684K0_LOTJA Pyruvate decarboxylase isozyme 1; Found in the gene: LotjaGi6g1v0324800
Domains
18
LotjaGi6g1v0333700.1
– Acetolactate synthase; TAIR: AT3G48560.1 chlorsulfuron/imidazolinone resistant 1; Swiss-Prot: sp|P09114|ILVB2_TOBAC Acetolactate synthase 2, chloroplastic; TrEMBL-Plants: tr|D2DJQ3|D2DJQ3_SOYBN Acetolactate synthase; Found in the gene: LotjaGi6g1v0333700
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd07035 CDD 1 5.56