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IPR029035 is a DHS-like NAD/FAD-binding domain superfamily.
<p>This superfamily represents a domain which adopts a Rossmann fold, similar to the FAD/NAD(P)-binding Rossmann fold domain. However, there are differences between these two domains. Proteins with this DHS-like NAD/FAD-binding domain bind cofactor in the opposite direction and lack the conserved GxGxxG motif found in classical NADP binding Rossmann folds. It also forms an internal hydrogen bond in the FAD molecule [[cite:PUB00019097]].</p> <p>This domain can be found in deoxyhypusine synthase (DHS), the C-terminal domain of the electron transfer flavoprotein alpha subunit, the central domain of the pyruvate oxidase and decarboxylase, transhydrogenase domain III (dIII), Sir2 family of transcriptional regulators and the CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit.</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: NAD-dependent protein deacetylase SRT2-like [Cicer arietinum] gi|502137108|ref|XP_004502971.1| | 11 | ||
– | PREDICTED: electron transfer flavoprotein subunit alpha, mitochondrial-like [Cicer arietinum] gi|502143739|ref|XP_004505448.1| | 19 | ||
– | PREDICTED: NAD-dependent ADP-ribosyltransferase sirtuin-4-like [Glycine max] gi|356518787|ref|XP_003528059.1| | 9 | ||
– | Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Theobroma cacao] gi|508715239|gb|EOY07136.1| | 19 | ||
– | PREDICTED: protein PHYLLO, chloroplastic-like [Cicer arietinum] gi|502154072|ref|XP_004509573.1| | 19 | ||
– | PREDICTED: protein PHYLLO, chloroplastic-like [Glycine max] gi|356555334|ref|XP_003545988.1| | 15 | ||
– | PREDICTED: NAD-dependent protein deacetylase SRT2-like [Cicer arietinum] gi|502137108|ref|XP_004502971.1| | 14 | ||
– | Acetolactate synthase [Medicago littoralis] gi|164453114|gb|ABY57316.1| | 20 | ||
– | Pyruvate decarboxylase 1 [Lotus corniculatus] gi|29373077|gb|AAO72533.1| | 18 | ||
– | Dhs1 [Glycine max] gi|351726826|ref|NP_001235604.1| | 8 | ||
– | Dhs1 [Glycine max] gi|351726826|ref|NP_001235604.1| | 9 | ||
– | PREDICTED: 2-hydroxyacyl-CoA lyase-like [Glycine max] gi|356553206|ref|XP_003544949.1| | 19 | ||
– | PREDICTED: NAD-dependent deacetylase sirtuin-6-like [Glycine max] gi|356566429|ref|XP_003551434.1| | 10 | ||
– | PREDICTED: NAD-dependent deacetylase sirtuin-6-like [Glycine max] gi|356566429|ref|XP_003551434.1| | 10 | ||
– | PREDICTED: NAD-dependent protein deacetylase SRT1-like [Cicer arietinum] gi|502177494|ref|XP_004516096.1| | 10 | ||
– | Pyruvate decarboxylase isozyme 1 [Lotus japonicus] gi|51587336|emb|CAG30578.1| | 18 | ||
– | 18 | |||
– | PREDICTED: acetolactate synthase 1, chloroplastic-like [Cicer arietinum] gi|502077817|ref|XP_004485753.1| | 20 | ||
– | 13 | |||
– | NAD-dependent protein deacylase; TAIR: AT5G09230.1 sirtuin 2; Swiss-Prot: sp|Q94AQ6|SIR4_ARATH NAD-dependent protein deacylase SRT2; TrEMBL-Plants: tr|A0A0S3REZ3|A0A0S3REZ3_PHAAN NAD-dependent protein deacylase; Found in the gene: LotjaGi1g1v0322700 | 13 | ||
– | Acetolactate synthase; TAIR: AT3G48560.1 chlorsulfuron/imidazolinone resistant 1; Swiss-Prot: sp|P09114|ILVB2_TOBAC Acetolactate synthase 2, chloroplastic; TrEMBL-Plants: tr|B0FBK4|B0FBK4_9FABA Acetolactate synthase; Found in the gene: LotjaGi1g1v0338500 | 21 | ||
– | Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800 | 18 | ||
– | Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|P51851|PDC2_PEA Pyruvate decarboxylase 2; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800 | 13 | ||
– | Pyruvate decarboxylase; TAIR: AT4G33070.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|O82647|PDC1_ARATH Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q84V95|Q84V95_LOTCO Pyruvate decarboxylase 1; Found in the gene: LotjaGi1g1v0443800 | 18 | ||
– | Deoxyhypusine synthase; TAIR: AT5G05920.1 deoxyhypusine synthase; Swiss-Prot: sp|Q9FI94|DHYS_ARATH Deoxyhypusine synthase; TrEMBL-Plants: tr|C6ZS19|C6ZS19_SOYBN Dhs1; Found in the gene: LotjaGi1g1v0610600 | 8 | ||
– | Acetolactate synthase; TAIR: AT5G17380.1 Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Swiss-Prot: sp|Q9LF46|HACL_ARATH 2-hydroxyacyl-CoA lyase; TrEMBL-Plants: tr|A0A151TX24|A0A151TX24_CAJCA 2-hydroxyacyl-CoA lyase 1; Found in the gene: LotjaGi2g1v0238100 | 19 | ||
– | Electron transfer flavoprotein subunit alpha, mitochondrial; TAIR: AT1G50940.1 electron transfer flavoprotein alpha; Swiss-Prot: sp|Q9C6I6|ETFA_ARATH Electron transfer flavoprotein subunit alpha, mitochondrial; TrEMBL-Plants: tr|I3SFR5|I3SFR5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0148500 | 19 | ||
– | Electron transfer flavoprotein subunit alpha; TAIR: AT1G50940.1 electron transfer flavoprotein alpha; Swiss-Prot: sp|Q9C6I6|ETFA_ARATH Electron transfer flavoprotein subunit alpha, mitochondrial; TrEMBL-Plants: tr|I3SFR5|I3SFR5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0148500 | 24 | ||
– | Electron transfer flavoprotein subunit alpha; TAIR: AT1G50940.1 electron transfer flavoprotein alpha; Swiss-Prot: sp|Q9C6I6|ETFA_ARATH Electron transfer flavoprotein subunit alpha, mitochondrial; TrEMBL-Plants: tr|I3SFR5|I3SFR5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0148500 | 19 | ||
– | Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000 | 19 | ||
– | Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000 | 19 | ||
– | Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|Q9FFT4|PDC2_ARATH Pyruvate decarboxylase 2; TrEMBL-Plants: tr|A0A061EQM3|A0A061EQM3_THECC Thiamine pyrophosphate dependent pyruvate decarboxylase family protein; Found in the gene: LotjaGi3g1v0195000 | 19 | ||
– | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; TAIR: AT1G68890.1 2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding protein; Swiss-Prot: sp|Q15KI9|PHYLO_ARATH Protein PHYLLO, chloroplastic; TrEMBL-Plants: tr|K7MEA2|K7MEA2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0153600 | 38 | ||
– | NAD-dependent protein deacetylase; TAIR: AT5G55760.1 sirtuin 1; Swiss-Prot: sp|Q9FE17|SIR1_ARATH NAD-dependent protein deacetylase SRT1; TrEMBL-Plants: tr|V7BPZ4|V7BPZ4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0142500 | 12 | ||
– | NAD-dependent protein deacetylase; TAIR: AT5G55760.1 sirtuin 1; Swiss-Prot: sp|Q9FE17|SIR1_ARATH NAD-dependent protein deacetylase SRT1; TrEMBL-Plants: tr|V7BPZ4|V7BPZ4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0142500 | 17 | ||
– | Pyruvate decarboxylase; TAIR: AT5G54960.1 pyruvate decarboxylase-2; Swiss-Prot: sp|P51850|PDC1_PEA Pyruvate decarboxylase 1; TrEMBL-Plants: tr|Q684K0|Q684K0_LOTJA Pyruvate decarboxylase isozyme 1; Found in the gene: LotjaGi6g1v0324800 | 18 | ||
– | Acetolactate synthase; TAIR: AT3G48560.1 chlorsulfuron/imidazolinone resistant 1; Swiss-Prot: sp|P09114|ILVB2_TOBAC Acetolactate synthase 2, chloroplastic; TrEMBL-Plants: tr|D2DJQ3|D2DJQ3_SOYBN Acetolactate synthase; Found in the gene: LotjaGi6g1v0333700 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd07035 | CDD | 1 | 2.70 |