Domain Predictions — View

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IPR018948

Source: InterPro

Description

IPR018948 is a GTP-binding protein TrmE, N-terminal.

<p>This entry represents the N-terminal domain of tRNA modification GTPase MnmE (also known as TrmE) and similar proteins found in bacteria and eukaryotes. MnmE is a guanine nucleotide-binding protein involved in the modification of the wobble position of certain tRNAs that binds and hydrolyses GTP. TrmE actively participates in the formylation reaction of uridine and regulates the ensuing hydrogenation reaction of a Schiff's base intermediate. This domain consists of five β-strands and three α-helices and is necessary for mediating dimer formation within the protein. It is homologous to the tetrahydrofolate-binding domain of N,N-dimethylglycine oxidase and indeed binds formyl-tetrahydrofolate [[cite:PUB00038393], [cite:PUB00075639]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 4

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0352669.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	TRNA modification GTPase mnmE [Medicago truncatula] gi\|358349532\|ref\|XP_003638789.1\|	Domains Coil G3DSA:1.20.120.430 G3DSA:3.30.1360.120 G3DSA:3.40.50.300 IPR004520 IPR005225 IPR006073 IPR018948 IPR025867 IPR027266 IPR027368 IPR027417 IPR031168 MF_00379 PF01926 PF10396 PF12631 PS51709 PTHR11649 PTHR11649:SF56 SSF52540 TIGR00231 TIGR00450 cd04164	24
Lj0g3v0352669.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: tRNA modification GTPase MnmE-like [Cicer arietinum] gi\|502130302\|ref\|XP_004500604.1\|	Domains Coil G3DSA:1.20.120.430 G3DSA:3.30.1360.120 G3DSA:3.40.50.300 IPR006073 IPR018948 IPR025867 IPR027266 IPR027368 IPR027417 PF01926 PF10396 PF12631 PTHR11649 PTHR11649:SF56 SSF103025 SSF116878	17
LotjaGi1g1v0246400.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	TRNA modification GTPase mnmE; TAIR: AT1G78010.1 tRNA modification GTPase; Swiss-Prot: sp\|Q3MBM5\|MNME_ANAVT tRNA modification GTPase MnmE; TrEMBL-Plants: tr\|G8A389\|G8A389_MEDTR tRNA modification GTPase trmE; Found in the gene: LotjaGi1g1v0246400	Domains Coil G3DSA:1.20.120.430 G3DSA:3.30.1360.120 G3DSA:3.40.50.300 IPR004520 IPR005225 IPR006073 IPR018948 IPR025867 IPR027266 IPR027368 IPR027417 IPR031168 MF_00379 PF01926 PF10396 PF12631 PS51709 PTHR42714 PTHR42714:SF1 SSF52540 TIGR00231 TIGR00450 cd04164	24
LotjaGi1g1v0246400.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	TRNA modification GTPase mnmE; TAIR: AT1G78010.1 tRNA modification GTPase; Swiss-Prot: sp\|Q3MBM5\|MNME_ANAVT tRNA modification GTPase MnmE; TrEMBL-Plants: tr\|K7KJB6\|K7KJB6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0246400	Domains Coil G3DSA:1.20.120.430 G3DSA:3.30.1360.120 G3DSA:3.40.50.300 IPR004520 IPR005225 IPR006073 IPR018948 IPR025867 IPR027266 IPR027368 IPR027417 IPR031168 PF01926 PF10396 PF12631 PTHR42714 PTHR42714:SF1 SSF103025 SSF52540 TIGR00231 TIGR00450 cd04164	23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd04164	CDD	1	25.00