Description

IPR019443 is a BLTP2/FMP27/Hobbit, C-terminal.

<p>This entry includes Hobbit protein from Drosophila melanogaster and its homologues such as Bridge-like lipid transfer protein family member 2 from human (BLTP2/KIAA0100) and FMP27 from yeast, referred to the Hob proteins [[cite:PUB00101860], [cite:PUB00101861]]. These proteins are localized to endoplasmic reticulum-plasma membrane (ER-PM) contact sites described as conserved lipid-binding proteins. They have a long hydrophobic groove and can mediate bulk transport of lipids between organelles. This entry also includes maize protein APT1 and Arabidopsis homologues SABRE and KIP [[cite:PUB00101861]]. The Hob family belongs to the repeating β-groove (RBG) superfamily together with VPS13, ATG2, SHIP164, Csf1/BLTP1, which are all conserved lipid transfer proteins containing long hydrophobic grooves [[cite:PUB00101861]]. They all share the same structure consisting of multiple repeating modules consisting of five β-sheets followed by a loop.</p> <p>This entry represents the C-terminal region of the Hobbit family of proteins. They belong to the repeating β-groove (RBG) superfamily together with VPS13, ATG2, SHIP164, Csf1/BLTP1, which are all conserved lipid transfer proteins containing long hydrophobic grooves [[cite:PUB00101861]]. They all share the same structure consisting of multiple repeating modules consisting of five β-sheets followed by a loop.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: