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IPR020672 is a Ribose-5-phosphate isomerase, type A, subgroup.
<p>Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the reversible conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate, the first step in the non-oxidative branch of the pentose phosphate pathway [[cite:PUB00028856]]. This reaction enables ribose to be synthesized from sugars, as well as the recycling of sugars during the degradation of nucleotides. There are two unrelated types of ribose 5-phosphate isomerases: type A (RpiA) is the most common and is found in most organisms, while type B (RpiB) is restricted to specific eukaryotic and prokaryotic species. Escherichia coli produces both RpiA and RpiB (also known as AlsB), although RpiA accounts for 99% of total RPI enzymes [[cite:PUB00020248]].</p> <p>This entry represents a subgroup of type A ribose-5-phosphate isomerase that is found in bacteria, archaea and eukaryotes (plants and Metazoa), but excluding those found in fungi.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Ribose-5-phosphate isomerase activity | Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate. | ||
Biological process | Pentose-phosphate shunt, non-oxidative branch | The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: probable ribose-5-phosphate isomerase-like [Glycine max] gi|356575632|ref|XP_003555942.1| | 13 | ||
– | PREDICTED: probable ribose-5-phosphate isomerase-like [Glycine max] gi|356575632|ref|XP_003555942.1| | 12 | ||
– | Ribose-5-phosphate isomerase A; TAIR: AT3G04790.1 Ribose 5-phosphate isomerase, type A protein; Swiss-Prot: sp|Q9S726|RPI3_ARATH Probable ribose-5-phosphate isomerase 3, chloroplastic; TrEMBL-Plants: tr|A0A151TXP4|A0A151TXP4_CAJCA Putative ribose-5-phosphate isomerase; Found in the gene: LotjaGi1g1v0780100 | 13 | ||
– | Ribose-5-phosphate isomerase A; TAIR: AT3G04790.1 Ribose 5-phosphate isomerase, type A protein; Swiss-Prot: sp|Q9S726|RPI3_ARATH Probable ribose-5-phosphate isomerase 3, chloroplastic; TrEMBL-Plants: tr|A0A151TXP4|A0A151TXP4_CAJCA Putative ribose-5-phosphate isomerase; Found in the gene: LotjaGi1g1v0780100 | 13 | ||
– | Ribose-5-phosphate isomerase A; TAIR: AT2G01290.1 ribose-5-phosphate isomerase 2; Swiss-Prot: sp|Q9ZU38|RPI2_ARATH Probable ribose-5-phosphate isomerase 2; TrEMBL-Plants: tr|A0A1J7FSX7|A0A1J7FSX7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0331100 | 13 | ||
– | Ribose-5-phosphate isomerase A; TAIR: AT2G01290.1 ribose-5-phosphate isomerase 2; Swiss-Prot: sp|Q9ZU38|RPI2_ARATH Probable ribose-5-phosphate isomerase 2; TrEMBL-Plants: tr|A0A1J7FSX7|A0A1J7FSX7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0331100 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd01398 | CDD | 1 | 16.67 |