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IPR004788 is a Ribose 5-phosphate isomerase, type A.
<p>Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the reversible conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate, the first step in the non-oxidative branch of the pentose phosphate pathway [[cite:PUB00028856]]. This reaction enables ribose to be synthesized from sugars, as well as the recycling of sugars during the degradation of nucleotides. There are two unrelated types of ribose 5-phosphate isomerases: type A (RpiA) is the most common and is found in most organisms, while type B (RpiB) is restricted to specific eukaryotic and prokaryotic species. Escherichia coli produces both RpiA and RpiB (also known as AlsB), although RpiA accounts for 99% of total RPI enzymes [[cite:PUB00020248]].</p> <p>This entry represents type A (RpiA) enzymes found in eukaryotes (plants, Metazoa and fungi), bacteria and archaea.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Ribose-5-phosphate isomerase activity | Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate. | ||
| Biological process | Pentose-phosphate shunt, non-oxidative branch | The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: ribose-5-phosphate isomerase A-like [Glycine max] gi|356555958|ref|XP_003546296.1| | 4 | ||
| – | PREDICTED: probable ribose-5-phosphate isomerase-like [Cucumis sativus] gi|449442917|ref|XP_004139227.1| | 11 | ||
| – | PREDICTED: probable ribose-5-phosphate isomerase-like [Glycine max] gi|356575632|ref|XP_003555942.1| | 13 | ||
| – | PREDICTED: probable ribose-5-phosphate isomerase-like [Glycine max] gi|356575632|ref|XP_003555942.1| | 12 | ||
| – | PREDICTED: probable ribose-5-phosphate isomerase-like [Cicer arietinum] gi|502080272|ref|XP_004486512.1| | 9 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT3G04790.1 Ribose 5-phosphate isomerase, type A protein; Swiss-Prot: sp|Q9S726|RPI3_ARATH Probable ribose-5-phosphate isomerase 3, chloroplastic; TrEMBL-Plants: tr|A0A151TXP4|A0A151TXP4_CAJCA Putative ribose-5-phosphate isomerase; Found in the gene: LotjaGi1g1v0780100 | 13 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT3G04790.1 Ribose 5-phosphate isomerase, type A protein; Swiss-Prot: sp|Q9S726|RPI3_ARATH Probable ribose-5-phosphate isomerase 3, chloroplastic; TrEMBL-Plants: tr|A0A151TXP4|A0A151TXP4_CAJCA Putative ribose-5-phosphate isomerase; Found in the gene: LotjaGi1g1v0780100 | 13 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT3G04790.1 Ribose 5-phosphate isomerase, type A protein; Swiss-Prot: sp|Q9S726|RPI3_ARATH Probable ribose-5-phosphate isomerase 3, chloroplastic; TrEMBL-Plants: tr|A0A0A0LFJ4|A0A0A0LFJ4_CUCSA Uncharacterized protein; Found in the gene: LotjaGi4g1v0234200_LC | 12 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT2G01290.1 ribose-5-phosphate isomerase 2; Swiss-Prot: sp|Q9ZU38|RPI2_ARATH Probable ribose-5-phosphate isomerase 2; TrEMBL-Plants: tr|A0A1J7FSX7|A0A1J7FSX7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0331100 | 13 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT2G01290.1 ribose-5-phosphate isomerase 2; Swiss-Prot: sp|Q9ZU38|RPI2_ARATH Probable ribose-5-phosphate isomerase 2; TrEMBL-Plants: tr|A0A1J7FSX7|A0A1J7FSX7_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0331100 | 13 | ||
| – | Ribose-5-phosphate isomerase A; TAIR: AT5G44520.2 NagB/RpiA/CoA transferase-like superfamily protein; Swiss-Prot: sp|Q9FI13|RPI4_ARATH Probable ribose-5-phosphate isomerase 4, chloroplastic; TrEMBL-Plants: tr|A0A1J7HLQ2|A0A1J7HLQ2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0264100 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01398 | CDD | 1 | 9.09 |