Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR023419 is a Transthyretin, conserved site.
<p>Transthyretin (prealbumin) is a thyroid hormone-binding protein that seems to transport thyroxine (T4) from the bloodstream to the brain. It is a protein of about 130 amino acids that assembles as a homotetramer and forms an internal channel that binds thyroxine. In humans, transthyretin is mainly synthesized in the brain choroid plexus; variants of the protein are associated with distinct forms of amyloidosis.</p> <p>The sequence of transthyretin is highly conserved in vertebrates. A number of uncharacterised proteins also belong to this family:</p> <ul> <li>Escherichia coli hypothetical protein YedX.</li> <li>Bacillus subtilis hypothetical protein YunM.</li> <li>Caenorhabditis elegans hypothetical protein R09H10.3.</li> <li>Caenorhabditis elegans hypothetical protein ZK697.8.</li> </ul> <p>The signature pattern in this entry is located at the C terminus.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: uric acid degradation bifunctional protein TTL-like isoform X2 [Cicer arietinum] gi|502155814|ref|XP_004510201.1| | 19 | ||
| – | PREDICTED: uric acid degradation bifunctional protein TTL-like isoform X1 [Cicer arietinum] gi|502155812|ref|XP_004510200.1| | 19 | ||
| – | Transthyretin-like S-allantoin synthase protein; TAIR: AT5G58220.1 transthyretin-like protein; Swiss-Prot: sp|Q9LVM5|TTHL_ARATH Uric acid degradation bifunctional protein TTL; TrEMBL-Plants: tr|I1MM35|I1MM35_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0260800 | 22 | ||
| – | Transthyretin-like S-allantoin synthase protein; TAIR: AT5G58220.1 transthyretin-like protein; Swiss-Prot: sp|Q9LVM5|TTHL_ARATH Uric acid degradation bifunctional protein TTL; TrEMBL-Plants: tr|I1MM36|I1MM36_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0260800 | 21 | ||
| – | Transthyretin-like S-allantoin synthase protein; TAIR: AT5G58220.1 transthyretin-like protein; Swiss-Prot: sp|Q9LVM5|TTHL_ARATH Uric acid degradation bifunctional protein TTL; TrEMBL-Plants: tr|A0A151QU94|A0A151QU94_CAJCA Uncharacterized protein; Found in the gene: LotjaGi3g1v0260800 | 26 | ||
| – | Transthyretin-like S-allantoin synthase protein; TAIR: AT5G58220.1 transthyretin-like protein; Swiss-Prot: sp|Q9LVM5|TTHL_ARATH Uric acid degradation bifunctional protein TTL; TrEMBL-Plants: tr|A0A151QU94|A0A151QU94_CAJCA Uncharacterized protein; Found in the gene: LotjaGi3g1v0260800 | 26 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd05822 | CDD | 1 | 16.67 |