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IPR024074

Description

IPR024074 is a Argininosuccinate synthetase, catalytic/multimerisation domain body.

<p>The argininosuccinate synthetase (AS) monomer is composed of a nucleotide binding domain and a catalytic/multimerisation domain. The catalytic/multimerisation domain can be subdivided in the body of the domain and a C-terminal tail involved in multimerisation, though this tail is not present in all sequences.</p> <p>This entry represents the body of the catalytic/multimerisation domain. It is a mixed α/β fold consisting of two four-stranded antiparallel β sheets arranged end-to-end to form a cradle for a cluster of five α helices. In general, the α helices of the domain are responsible for multimerisation interactions, whereas the β sheets form the solvent-exposed surface [[cite:PUB00028813]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Argininosuccinate synthase activity Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.

Associated Lotus transcripts 21

Transcript Name Description Predicted domains Domain count
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 6
6
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 7
PREDICTED: argininosuccinate synthase, chloroplastic-like [Cicer arietinum] gi|502176214|ref|XP_004515824.1| 14
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 7
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 15
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 17
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 12
Argininosuccinate synthase [Medicago truncatula] gi|357463609|ref|XP_003602086.1| 6
6
PREDICTED: LOW QUALITY PROTEIN: argininosuccinate synthase, chloroplastic-like [Glycine max] gi|356514007|ref|XP_003525699.1| 7
7
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7J524|G7J524_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi1g1v0236700 16
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|A0A0L9TQ70|A0A0L9TQ70_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0237100_LC 12
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7J524|G7J524_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi1g1v0237200 17
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7J524|G7J524_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi1g1v0527800 22
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7J524|G7J524_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi1g1v0607700 22
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7J524|G7J524_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi1g1v0607700 17
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|I1MUN6|I1MUN6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0122200 17
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|I1MUN6|I1MUN6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0223000 17
Argininosuccinate synthase; TAIR: AT4G24830.1 arginosuccinate synthase family; Swiss-Prot: sp|Q9SZX3|ASSY_ARATH Argininosuccinate synthase, chloroplastic; TrEMBL-Plants: tr|G7JWM6|G7JWM6_MEDTR Argininosuccinate synthase; Found in the gene: LotjaGi4g1v0223000 17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01999 CDD 1 4.76