Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR024576 is a Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381.
<p>This uncharacterised domain is found in the central region of fungal SPB1 and mammalian homologue FTSJ3.</p> <p>SPB1 is an adoMet-dependent rRNA methyltransferase required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit [[cite:PUB00016377]]. In Saccharomyces cerevisiae, it specifically methylates the guanosine in position 2922 of the 25S rRNA at the stage of 27S pre-rRNA maturation [[cite:PUB00056208]]. It interacts with the snoRNA-associated proteins Nop1 and Nop58 [[cite:PUB00068804]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: adoMet-dependent rRNA methyltransferase spb1-like [Glycine max] gi|356538763|ref|XP_003537870.1| | 13 | ||
| – | Ribosomal RNA large subunit methyltransferase E; TAIR: AT4G25730.1 FtsJ-like methyltransferase family protein; Swiss-Prot: sp|Q5BH88|SPB1_EMENI AdoMet-dependent rRNA methyltransferase spb1; TrEMBL-Plants: tr|G7JTV9|G7JTV9_MEDTR Putative rRNA methyltransferase; Found in the gene: LotjaGi3g1v0509400 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |