Description

IPR026489 is a CXC domain.

<p>Polycomb group (Pc-G) proteins ensure the stable inheritance of expression patterns through cell division and regulate the control of cell proliferation. The Enhancer of zeste (E(z))-type of Pc-G proteins includes:<ul> <li>Drosophila melanogaster Enhancer of zeste E(z).</li> <li>Mammalian ENX-1 and ENX-2.</li> <li>Arabidopsis thaliana CURLY LEAF (CLF), a transcriptional repressor of floral homeotic gene AGAMOUS.</li> <li>Arabidopsis thaliana CLF-like.</li> <li>Arabidopsis thaliana MEDEA (MEA), a suppressor of endosperm development.</li> <li>Arabidopsis thaliana EZA1.</li> </ul>These proteins contain a SET domain at the C terminus. Unique to them is the presence of a CXC domain, an ~65-residue cys-rich region preceding the SET domain. The spacing of 17 cyteines is conserved. The CXC domain contains three units of C-X(6)-C-X(3)-C-X-C motif, although the most C- terminal unit is reverse-oriented. Because of its evolutionary conservation, the CXC domain is likely to be involved in an important function of E(z)- related proteins [[cite:PUB00060503], [cite:PUB00060504], [cite:PUB00060505]]. The CXC domain shows some similarity to the CRC domain found in the tesmin/ TSO1 protein family [[cite:PUB00057402]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: