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IPR026610

Source: InterPro

Description

IPR026610 is a 3'-RNA ribose 2'-O-methyltransferase, Hen1.

<p>This entry consists of the eukaryal and bacterial 3'-RNA ribose 2'-O-methyltransferase, Hen1. Eukaryal Hen1 is a methyltransferase that adds a 2'-O-methyl group at the 3'-end small RNAs to protects the 3'-end of sRNAs from uridylation activity and subsequent degradation [[cite:PUB00060819]]. In bacetria, Hen1 catalyses the same chemical reaction, but forms Pnkp/Hen1 heterotetramer and is involved in RNA repair [[cite:PUB00055068], [cite:PUB00056235]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0001510
Biological process RNA methylation Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
Subterm of
GO:0008171
Molecular function O-methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
Subterm of
GO:0008173
Molecular function RNA methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj4g3v0286120.1
– PREDICTED: small RNA 2'-O-methyltransferase-like [Glycine max] gi|356510770|ref|XP_003524107.1|
Domains
12
LotjaGi4g1v0026400.1
– Small RNA 2'-O-methyltransferase; TAIR: AT4G20910.1 double-stranded RNA binding protein-related / DsRBD protein-like protein; Swiss-Prot: sp|Q9C5Q8|HEN1_ARATH Small RNA 2'-O-methyltransferase; TrEMBL-Plants: tr|I1K2Z2|I1K2Z2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0026400
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF54768 SUPERFAMILY 1 50.00