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IPR038737 is a Splicing factor 3B subunit 1-like.
<p>This entry includes animal splicing factor 3B subunit 1 (SF3B1, also known as SAP 155) and its homologues such as Hsh155 from budding yeasts [[cite:PUB00063197]] and Prp10 from fission yeasts [[cite:PUB00088333]]. SF3B1 is a component of the splicing factor SF3B complex, which is important for anchoring the spliceosome to precursor mRNA. SF3B1 binds to pre-mRNA on both sides of the intron branch site region [[cite:PUB00088342]]. This subunit is required for 'A' splicing complex assembly (formed by the stable binding of U2 snRNP to the branchpoint sequence in pre-mRNA) and 'E' splicing complex assembly [[cite:PUB00035461]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Spliceosomal complex assembly | The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. | ||
| Molecular function | MRNA binding | Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Splicing factor 3B subunit 1; TAIR: AT5G64270.1 splicing factor; Swiss-Prot: sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1; TrEMBL-Plants: tr|V7BPY5|V7BPY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0351100 | 17 | ||
| – | Splicing factor 3B subunit 1; TAIR: AT5G64270.1 splicing factor; Swiss-Prot: sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1; TrEMBL-Plants: tr|V7BPY5|V7BPY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0351100 | 17 | ||
| – | Splicing factor 3B subunit 1; TAIR: AT5G64270.1 splicing factor; Swiss-Prot: sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1; TrEMBL-Plants: tr|V7BPY5|V7BPY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0351100 | 15 | ||
| – | Splicing factor 3B subunit 1; TAIR: AT5G64270.1 splicing factor; Swiss-Prot: sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1; TrEMBL-Plants: tr|V7BPY5|V7BPY5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0351100 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |