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IPR038846 is a DNA-directed RNA polymerase III subunit RPC9.
<p>RPC9, also known as Rpc17 in budding yeasts, is a subunit of DNA-directed RNA polymerase III that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It may be involved in the recruitment of pol III by the preinitiation complex [[cite:PUB00056255], [cite:PUB00088483]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Cellular component | RNA polymerase III complex | RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. | ||
Biological process | Transcription initiation from RNA polymerase III promoter | Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O35427|RPC9_MOUSE DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0155200 | 11 | ||
– | RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O35427|RPC9_MOUSE DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0155200 | 11 | ||
– | RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|A0JN61|RPC9_BOVIN DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0059100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 33.33 |