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IPR005574

Description

IPR005574 is a RNA polymerase subunit Rpb4/RPC9.

<p>This entry includes RNA polymerase II subunit Rpb4 and its paralogue, RPC9 (also known as Rpc17 in budding yeasts), a subunit of RNA polymerase III [[cite:PUB00088484]]. The Rpb4 and Rpb7 subunits of yeast RNA polymerase II form a heterodimeric complex essential for promoter-directed transcription initiation. The Rpb4-Rpb7 complex is not required for stable recruitment of polymerase to active preinitiation complexes, suggesting that Rpb4-Rpb7 mediates an essential step subsequent to promoter binding [[cite:PUB00007967]]. RPC9 may be involved in the recruitment of pol III by the preinitiation complex [[cite:PUB00056255], [cite:PUB00088483]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process DNA-templated transcription, initiation Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
Cellular component RNA polymerase complex Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.

Associated Lotus transcripts 11

Transcript Name Description Predicted domains Domain count
PREDICTED: DNA-directed RNA polymerase II subunit RPB4-like [Cicer arietinum] gi|502153857|ref|XP_004509486.1| 7
PREDICTED: DNA-directed RNA polymerase III subunit rpc9-like [Glycine max] gi|356569570|ref|XP_003552972.1| 9
PREDICTED: DNA-directed RNA polymerase III subunit rpc9-like [Glycine max] gi|356569570|ref|XP_003552972.1| 9
PREDICTED: DNA-directed RNA polymerase III subunit rpc9-like [Glycine max] gi|356569570|ref|XP_003552972.1| 8
PREDICTED: DNA-directed RNA polymerase II subunit rpb4-like [Glycine max] gi|356532865|ref|XP_003534990.1| 9
DNA-directed RNA polymerase II subunit RPB4; TAIR: AT5G09920.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O48890|NRPB4_ARATH DNA-directed RNA polymerase II subunit 4; TrEMBL-Plants: tr|I3S6N6|I3S6N6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0090700 10
DNA-directed RNA polymerase II subunit RPB4; TAIR: AT5G09920.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O48890|NRPB4_ARATH DNA-directed RNA polymerase II subunit 4; TrEMBL-Plants: tr|A0A0L9VU29|A0A0L9VU29_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0090700 10
RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O35427|RPC9_MOUSE DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0155200 11
RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|O35427|RPC9_MOUSE DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0155200 11
RNA polymerase II, Rpb4, core protein; TAIR: AT5G62950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|A0JN61|RPC9_BOVIN DNA-directed RNA polymerase III subunit RPC9; TrEMBL-Plants: tr|I3SAG6|I3SAG6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0059100 11
DNA-directed RNA polymerase II subunit rpb4; TAIR: AT4G15950.1 RNA polymerase II, Rpb4, core protein; Swiss-Prot: sp|Q6DBA5|NRPD4_ARATH DNA-directed RNA polymerases IV and V subunit 4; TrEMBL-Plants: tr|A0A151T6X0|A0A151T6X0_CAJCA DNA-directed RNA polymerase II subunit rpb4; Found in the gene: LotjaGi6g1v0280900 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 9.09