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IPR040072 is a Methyltransferase (Class A).
<p>The enzymes in this subgroup represent the Class A Radical SAM Methyltransferases. These proteins all have a single canonical Radical SAM core domain and utilise a methylene radical generated on a unique methylated cysteine residues. They use two moles of SAM per turnover, the first being a methyl donor, methylating the conserved Cys residue and the other being reductively cleaved to form the 5'-deoxyadenosyl radical and Methionine [[cite:PUB00083544], [cite:PUB00084272], [cite:PUB00083545], [cite:PUB00090501], [cite:PUB00090502], [cite:PUB00090503]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Dual-specificity RNA methyltransferase RlmN; TAIR: AT2G39670.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q8DG98|RLMN_THEEB Probable dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|G7KBR0|G7KBR0_MEDTR 23S rRNA m2A2503 methyltransferase; Found in the gene: LotjaGi1g1v0090900 | 24 | ||
| – | Dual-specificity RNA methyltransferase RlmN; TAIR: AT3G19630.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q6MDD0|RLMN2_PARUW Probable dual-specificity RNA methyltransferase RlmN 2; TrEMBL-Plants: tr|I3T8H2|I3T8H2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0459900 | 15 | ||
| – | Dual-specificity RNA methyltransferase RlmN; TAIR: AT3G19630.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q6MDD0|RLMN2_PARUW Probable dual-specificity RNA methyltransferase RlmN 2; TrEMBL-Plants: tr|I3T8H2|I3T8H2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0459900 | 7 | ||
| – | Dual-specificity RNA methyltransferase RlmN; TAIR: AT1G60230.1 Radical SAM superfamily protein; Swiss-Prot: sp|A0LQM1|RLMN_SYNFM Dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|I1KXG4|I1KXG4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0165700 | 23 | ||
| – | Dual-specificity RNA methyltransferase RlmN; TAIR: AT1G60230.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q3A2Z4|RLMN_PELCD Dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|V7C8D7|V7C8D7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0165700 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01335 | CDD | 1 | 20.00 |