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IPR027492

Source: InterPro

Description

IPR027492 is a Dual-specificity RNA methyltransferase RlmN.

<p>Dual-specificity RNA methyltransferase RlmN specifically methylates position 2 of adenine 2503 in 23S rRNA, which serves to optimize ribosomal fidelity, and position 2 of adenine 37 in tRNAs. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation [[cite:PUB00046147], [cite:PUB00064728], [cite:PUB00064729]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0030488
Biological process TRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
Subterm of
GO:0070475
Biological process RRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj2g3v2585500.1
– PREDICTED: probable dual-specificity RNA methyltransferase RlmN-like [Cicer arietinum] gi|502097051|ref|XP_004490899.1|
Domains
22
LotjaGi1g1v0090900.1
– Dual-specificity RNA methyltransferase RlmN; TAIR: AT2G39670.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q8DG98|RLMN_THEEB Probable dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|G7KBR0|G7KBR0_MEDTR 23S rRNA m2A2503 methyltransferase; Found in the gene: LotjaGi1g1v0090900
Domains
24
LotjaGi4g1v0165700.1
– Dual-specificity RNA methyltransferase RlmN; TAIR: AT1G60230.1 Radical SAM superfamily protein; Swiss-Prot: sp|A0LQM1|RLMN_SYNFM Dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|I1KXG4|I1KXG4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0165700
Domains
23
LotjaGi4g1v0165700.2
– Dual-specificity RNA methyltransferase RlmN; TAIR: AT1G60230.1 Radical SAM superfamily protein; Swiss-Prot: sp|Q3A2Z4|RLMN_PELCD Dual-specificity RNA methyltransferase RlmN; TrEMBL-Plants: tr|V7C8D7|V7C8D7_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0165700
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01335 CDD 1 25.00