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IPR042163

Source: InterPro

Description

IPR042163 is a PHD finger protein 12.

<p>PHF12, also known as Pf1, is a PHD zinc finger protein that binds TLE (transducin-like enhancer) in an mSin3A-independent manner and recruits functional TLE complexes to repress transcription [[cite:PUB00092756]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003714
Molecular function Transcription corepressor activity A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A third class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
Subterm of
GO:0045892
Biological process Negative regulation of transcription, DNA-templated Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
Subterm of
Negatively regulates

Associated Lotus transcripts 13

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0134000_LC.1
– PHD finger family protein; TAIR: AT5G44800.1 chromatin remodeling 4; Swiss-Prot: sp|F4KBP5|CHR4_ARATH Protein CHROMATIN REMODELING 4; TrEMBL-Plants: tr|K7KPZ4|K7KPZ4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0134000_LC
Domains
15
LotjaGi3g1v0147600_LC.1
– PHD finger family protein; TAIR: AT5G44800.1 chromatin remodeling 4; Swiss-Prot: sp|F4KBP5|CHR4_ARATH Protein CHROMATIN REMODELING 4; TrEMBL-Plants: tr|A0A176VP64|A0A176VP64_MARPO Uncharacterized protein; Found in the gene: LotjaGi3g1v0147600_LC
Domains
15
LotjaGi3g1v0147600_LC.2
– PHD finger family protein; TAIR: AT5G44800.1 chromatin remodeling 4; Swiss-Prot: sp|F4KBP5|CHR4_ARATH Protein CHROMATIN REMODELING 4; TrEMBL-Plants: tr|A0A176VP64|A0A176VP64_MARPO Uncharacterized protein; Found in the gene: LotjaGi3g1v0147600_LC
Domains
15
LotjaGi3g1v0147700_LC.1
– PHD finger family protein; TAIR: AT5G44800.1 chromatin remodeling 4; Swiss-Prot: sp|F4KBP5|CHR4_ARATH Protein CHROMATIN REMODELING 4; TrEMBL-Plants: tr|A0A176VP64|A0A176VP64_MARPO Uncharacterized protein; Found in the gene: LotjaGi3g1v0147700_LC
Domains
15
LotjaGi3g1v0158900.1
– Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; TAIR: AT3G14980.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|A0A072VAI1|A0A072VAI1_MEDTR RING/FYVE/PHD zinc finger protein; Found in the gene: LotjaGi3g1v0158900
Domains
21
LotjaGi4g1v0198600_LC.1
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
22
LotjaGi4g1v0198600_LC.2
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
22
LotjaGi4g1v0198600_LC.3
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
22
LotjaGi4g1v0198600_LC.4
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
22
LotjaGi4g1v0198600_LC.5
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
22
LotjaGi4g1v0198600_LC.6
– Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein, putative; TAIR: AT4G14920.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198600_LC
Domains
6
LotjaGi4g1v0198800_LC.1
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT1G05380.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198800_LC
Domains
23
LotjaGi4g1v0198800_LC.2
– RING/FYVE/PHD zinc finger protein, putative; TAIR: AT4G14920.1 Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein; Swiss-Prot: sp|F4IXE7|IDM1_ARATH Increased DNA methylation 1; TrEMBL-Plants: tr|V7B190|V7B190_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0198800_LC
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 7.69