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| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0565200 |
| Transcript ID | LotjaGi1g1v0565200.6 |
| Related isoforms 7 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Dihydrofolate reductase / thymidylate synthase; TAIR: AT4G34570.1 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:109857301..109860468) extracted from Lotus japonicus Gifu genome v1.2.
ATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTA CCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCA AGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAG AGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAAC GGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTG AGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGGTATATGTTCTTCTCCCCCTTCTTGTGCTCCATCCTTTTCTGC TATAGACTTATGGCTGATAATTTCAATGTACAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACTGAAA TTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTTTCCT AAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTCAGAA TACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATGATTC TTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAGGACA GGGACTGGTACCTTGTCAAAATTTGGTTGCCAGGTAATGTGTCAATTGATATATTGAGTTTATCATAATTTATATGCTGA CTTTATCTCTATAATTCTACAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCAAGGCATGCAATTGTG GTTATGGTTTAGGATATGTTTTTAATCTACTGTGCAAAACATTATTTTCTTTTTAATTACTTTGGATGTTTACGGTTAAA GAGGAATGTCTATTTGTACATTTTGATAGAGAAGCTGACATGATTTCTTCATTGGGTTTCTAGAAAGTATTTTGGCGAGG GGTTGTTGAAGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGGTAATTATAACTTTTGACAATCTTTTCTACA CACATGAATATGGTATGTACTAGTCCCTTAGGTTTGGTTATGTGGTGTTGAACAGTAAAATCTGGTTGTAATTCTTTCTA GCTCCTTCGTTTTTGTGCTACTTTGTTGGTATAGTAGATAAGGACATACGGTTATTATGACCTATATTCAGAAAGCATTC TATATTGACAGGTGTTGCAGGAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGGCAAGCA TGATTGTCATTTGTTCAACTTTTAAATACAGATTGTACACTTATCTTCTTCTTGCAGTTACTAACTGGCATTACATTTTT TTACTACAGTATTGGTTTGACAGAGAGGGAGGAGGGTGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTG CCAGGTAGGTGGACAACTAGTTATTTTTCTCAGGTGGTGAATATTTAATAAACTGTTTAATGTGGCATTGCTCTGCTCTT TACTTTCCATCTTACATTTTATAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCAGCTTTTAGATG TTATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATCTTAAATTGATG GCACTTCCACCCTGCCACATGTTTGCACAGGTCTGCAGCTTTAGTTAGGGTTCTCTTTGAAAAGTCTCCCTCTCCTTTTT AAATCTTTTAATTTTTGTTAATTTTTAATTTGTAACTTGCAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTA TCAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATG TTTGTGGTATGTAAATGATCAAAGCATTTGCTATAGACTTAAATATTATCATGTGTATACTTCATCGTAAATGTTGAGGT TTCCAGCTGTAATGAGAGGTGATGTAATGCCATTTCATTTTGTTGTAAATGGCTTTAAGCATAATAATTGGTGGTGGTTC TCATAGATTTATTGTCATGATCCAATTTATTTTCTTTACAGGGGGGTGGGGGGTAATAATATGACTTTAATGTGCTCAGC TCAGCCCAAGCCTGATTTTATTTGTTTAACTAAGATTGACGCTTGAAACTTCGCCTCAGTTGGTTTGTTAAAAAGTTAAA ACTAATATTTTCTTTTGGACTTCAGTCATGTGAAGAAGTTGATTAGTATCTTCTGAAGTTTTGCATTCAAGATTATGAAG CTTTTATTTTTCTGTTGTTTTTTTTGGTTATATTTTATCACATAATGCACTTTCCATCATTTTTATAGCTTTTTTGTTAG GGTTGTTTCAGAAGAAATTTGTCAGTAAGTTTTTGTTTCACCACTGAGGGTTGGTTGTAGTTGGGTTCAGGTTCGAGAAG TTTATTGGGTTGATAAGATTACAATTGAAAAAATACAGCTCCAAAAAGTGCTTTAAAAATTGACTAAACAAATCCTTTTT TTTTTTCATTTCAGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGGC CTTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTGTATGTGTGAATACTTTAGAAAATTATTTGCTTTACATA ATTGGCCACAAATATTTTACCATTTATCACTCCTTTAGATTTGTGTCTTTTGACTCTTTACTCTTTAGTCTTGATGACTA TCTTAACTCCAATGCAGACTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCTGCTGATTTCAAGCTT GTAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
CDS sequence (LotjaGi1g1v0565200.6) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTA CCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCA AGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAG AGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAAC GGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTG AGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACT GAAATTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTT TCCTAAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTC AGAATACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATG ATTCTTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAG GACAGGGACTGGTACCTTGTCAAAATTTGGTTGCCAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCA AGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGTATTGGTTTGACAGAGAGGGAGGAGGGTGACTTAGGACCT GTTTATGGGTTTCAGTGGAGGCACTTTGGTGCCAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCA GCTTTTAGATGTTATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATC TTAAATTGATGGCACTTCCACCCTGCCACATGTTTGCACAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTAT CAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATGT TTGTGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGGCCTTTGCAGG AGCAGCTTCTTAACCTACCTAAACCTTTTCCTACTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCT GCTGATTTCAAGCTTGTAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
Protein sequence (LotjaGi1g1v0565200.6) extracted from Lotus japonicus Gifu v1.2 Proteins.
MTGDSFVVSSGNGNGSINPLPNLQRTYQVVVAATKDMGIGKDGKLPWRLFTDLKFFKEITTATSDPGKKNAIVMGRKTWE SIPLKYRPLPGRLNVVLTRSGSFDIGTAENVVICGSISSALELLAASPYCLSIEKVFVIGGGQIFREVLNAPGCEAIHFT EIHASIECDTFMPPVDSTKYQLWYSSFPKVENDIRYSFATYVRVQSSAAESLSQNTDPLFDNNSDSLKFEVQNFDFLPEM ILQRHEEYMYLRLIQEIISEGTTKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKNFFGLSVAQQMPSIGLTEREEGDLGP VYGFQWRHFGARYSDMHKDYSGQGYDQLLDVINKIKHNPNDRRIILSAWNPVDLKLMALPPCHMFAQFFVANGELSCQMY QRSADMGLGVPFNIASYALLTCMIAHVCELVPGDFVHVIGDAHVYHNHVRPLQEQLLNLPKPFPTLKINSEKKDIDSFVA ADFKLVGYNPHQKIEMKMAV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PIRSF | 14 | 305 | 292 | 1.8E-106 | ||
| Gene3D | 14 | 204 | 191 | 1.6E-59 | ||
| SUPERFAMILY | 18 | 203 | 186 | 1.7E-58 | ||
| PANTHER | 23 | 302 | 280 | 7.3E-252 | – | |
| PANTHER | 23 | 302 | 280 | 7.3E-252 | – | |
| ProSiteProfiles | 26 | 203 | 178 | 51.57 | ||
| Pfam | 28 | 203 | 176 | 2.1E-39 | ||
| CDD | 30 | 202 | 173 | 3.44795E-61 | ||
| ProSitePatterns | 38 | 60 | 23 | - | ||
| SUPERFAMILY | 235 | 500 | 266 | 1.7E-112 | ||
| Gene3D | 240 | 303 | 64 | 4.3E-17 | ||
| Pfam | 249 | 303 | 55 | 8.6E-14 | ||
| CDD | 250 | 453 | 204 | 2.91574E-96 | ||
| PRINTS | 288 | 309 | 22 | 1.5E-32 | ||
| PIRSF | 302 | 500 | 199 | 4.1E-115 | ||
| Gene3D | 304 | 500 | 197 | 1.3E-94 | ||
| PANTHER | 305 | 500 | 196 | 7.3E-252 | – | |
| PANTHER | 305 | 500 | 196 | 7.3E-252 | – | |
| Pfam | 313 | 500 | 188 | 1.3E-75 | ||
| TIGRFAM | 313 | 500 | 188 | 1.0E-73 | ||
| ProSitePatterns | 362 | 390 | 29 | - | ||
| PRINTS | 377 | 392 | 16 | 1.5E-32 | ||
| PRINTS | 395 | 421 | 27 | 1.5E-32 | ||
| PRINTS | 433 | 450 | 18 | 1.5E-32 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. | ||
| Molecular function | Thymidylate synthase activity | Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. | ||
| Biological process | DTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). | ||
| Biological process | One-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. | ||
| Biological process | Tetrahydrofolate biosynthetic process | The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi1g1v0565200.6, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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