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| Field | Value |
|---|---|
| Gene ID | LotjaGi1g1v0565200 |
| Transcript ID | LotjaGi1g1v0565200.3 |
| Related isoforms 7 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr1:109857062..109860468) extracted from Lotus japonicus Gifu genome v1.2.
ATGCTGTCACAATGTAAATTGCTTAGGTCTTTTCTGCATATCCTCATTTTTTTTTTCTTATGCTGTATGTATGCATTTCA TCTGATCTTGTTTTGCATGAGTGGTGCCACTTATAATTATTAACTTTGATTTATTACGTTTTTGAGTTTCAGATTCCACT GCAGTTCCCGAAGAATAGGCCGTGCAGCCCTTGTTTTCAGACGGTGTCTTCGAGCTTCTGTCGGTTTTTGAGTTCTATGA TGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGACTTAC CAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATCTCAA GTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGGGAGA GTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGGAACG GCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAATTGA GAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGGTATATGTTCTTCTCCCCCTTCTTGTGCTCCATCCTTTTCTGCT ATAGACTTATGGCTGATAATTTCAATGTACAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTCACTGAAAT TCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATCCTTTCCTA AGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGAGTCAGAAT ACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAAATGATTCT TCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGATAGGACAG GGACTGGTACCTTGTCAAAATTTGGTTGCCAGGTAATGTGTCAATTGATATATTGAGTTTATCATAATTTATATGCTGAC TTTATCTCTATAATTCTACAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAACCAAGGCATGCAATTGTGG TTATGGTTTAGGATATGTTTTTAATCTACTGTGCAAAACATTATTTTCTTTTTAATTACTTTGGATGTTTACGGTTAAAG AGGAATGTCTATTTGTACATTTTGATAGAGAAGCTGACATGATTTCTTCATTGGGTTTCTAGAAAGTATTTTGGCGAGGG GTTGTTGAAGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGGTAATTATAACTTTTGACAATCTTTTCTACAC ACATGAATATGGTATGTACTAGTCCCTTAGGTTTGGTTATGTGGTGTTGAACAGTAAAATCTGGTTGTAATTCTTTCTAG CTCCTTCGTTTTTGTGCTACTTTGTTGGTATAGTAGATAAGGACATACGGTTATTATGACCTATATTCAGAAAGCATTCT ATATTGACAGGTGTTGCAGGAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGGCAAGCAT GATTGTCATTTGTTCAACTTTTAAATACAGATTGTACACTTATCTTCTTCTTGCAGTTACTAACTGGCATTACATTTTTT TACTACAGTATTGGTTTGACAGAGAGGGAGGAGGGTGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTGC CAGGTAGGTGGACAACTAGTTATTTTTCTCAGGTGGTGAATATTTAATAAACTGTTTAATGTGGCATTGCTCTGCTCTTT ACTTTCCATCTTACATTTTATAGGTATAGTGACATGCATAAGGACTACTCCGGCCAAGGATATGATCAGCTTTTAGATGT TATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGGAATCCAGTTGATCTTAAATTGATGG CACTTCCACCCTGCCACATGTTTGCACAGGTCTGCAGCTTTAGTTAGGGTTCTCTTTGAAAAGTCTCCCTCTCCTTTTTA AATCTTTTAATTTTTGTTAATTTTTAATTTGTAACTTGCAGTTCTTTGTAGCAAATGGAGAATTATCATGTCAAATGTAT CAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCATGATTGCTCATGT TTGTGGTATGTAAATGATCAAAGCATTTGCTATAGACTTAAATATTATCATGTGTATACTTCATCGTAAATGTTGAGGTT TCCAGCTGTAATGAGAGGTGATGTAATGCCATTTCATTTTGTTGTAAATGGCTTTAAGCATAATAATTGGTGGTGGTTCT CATAGATTTATTGTCATGATCCAATTTATTTTCTTTACAGGGGGGTGGGGGGTAATAATATGACTTTAATGTGCTCAGCT CAGCCCAAGCCTGATTTTATTTGTTTAACTAAGATTGACGCTTGAAACTTCGCCTCAGTTGGTTTGTTAAAAAGTTAAAA CTAATATTTTCTTTTGGACTTCAGTCATGTGAAGAAGTTGATTAGTATCTTCTGAAGTTTTGCATTCAAGATTATGAAGC TTTTATTTTTCTGTTGTTTTTTTTGGTTATATTTTATCACATAATGCACTTTCCATCATTTTTATAGCTTTTTTGTTAGG GTTGTTTCAGAAGAAATTTGTCAGTAAGTTTTTGTTTCACCACTGAGGGTTGGTTGTAGTTGGGTTCAGGTTCGAGAAGT TTATTGGGTTGATAAGATTACAATTGAAAAAATACAGCTCCAAAAAGTGCTTTAAAAATTGACTAAACAAATCCTTTTTT TTTTTCATTTCAGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTGCGGCC TTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTGTATGTGTGAATACTTTAGAAAATTATTTGCTTTACATAA TTGGCCACAAATATTTTACCATTTATCACTCCTTTAGATTTGTGTCTTTTGACTCTTTACTCTTTAGTCTTGATGACTAT CTTAACTCCAATGCAGACTTTGAAGATAAATTCAGAGAAGAAAGATATAGACTCTTTTGTAGCTGCTGATTTCAAGCTTG TAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
CDS sequence (LotjaGi1g1v0565200.3) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGATGACTGGTGATTCTTTTGTAGTCTCTAGTGGAAATGGCAATGGCAGTATCAACCCACTACCTAATCTGCAGAGGAC TTACCAAGTGGTGGTTGCTGCCACCAAAGATATGGGCATTGGTAAGGATGGAAAATTACCCTGGAGATTATTTACCGATC TCAAGTTTTTTAAGGAGATCACTACCGCAACATCTGATCCCGGGAAGAAGAATGCCATAGTAATGGGAAGAAAAACATGG GAGAGTATCCCTCTTAAGTATAGGCCTCTACCCGGTCGGCTTAATGTTGTTCTCACACGCTCAGGTAGCTTTGATATTGG AACGGCAGAGAATGTTGTGATTTGTGGAAGTATCTCTTCTGCATTAGAACTTTTAGCTGCTTCTCCTTACTGTCTGTCAA TTGAGAAAGTATTTGTCATAGGAGGCGGTCAGATATTTAGAGAAGTTCTTAATGCACCTGGATGTGAAGCTATCCACTTC ACTGAAATTCATGCAAGCATTGAGTGTGACACTTTTATGCCTCCAGTTGATTCCACTAAATATCAGTTATGGTACTCATC CTTTCCTAAGGTGGAAAACGACATCCGCTATTCTTTCGCCACGTATGTGCGTGTTCAGAGTTCTGCAGCAGAGTCCCTGA GTCAGAATACTGATCCACTTTTTGATAATAATTCAGATTCCCTAAAGTTTGAGGTTCAAAACTTTGACTTTCTTCCTGAA ATGATTCTTCAGAGACATGAGGAATACATGTATCTTAGGCTGATTCAAGAAATCATATCTGAAGGTACAACTAAGGATGA TAGGACAGGGACTGGTACCTTGTCAAAATTTGGTTGCCAGATGAGGTTCAATCTCCGCAGAAGCTTTCCTCTTCTAACAA CCAAGAAAGTATTTTGGCGAGGGGTTGTTGAAGAACTTCTTTGGTTTATCAGTGGCTCAACAAATGCCAAGGTGTTGCAG GAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGAGAATACCTGGATAGTATTGGTTTGACAGAGAGGGAGGAGGG TGACTTAGGACCTGTTTATGGGTTTCAGTGGAGGCACTTTGGTGCCAGGTATAGTGACATGCATAAGGACTACTCCGGCC AAGGATATGATCAGCTTTTAGATGTTATTAACAAGATAAAGCATAATCCTAATGATCGACGTATCATTCTCTCTGCATGG AATCCAGTTGATCTTAAATTGATGGCACTTCCACCCTGCCACATGTTTGCACAGTTCTTTGTAGCAAATGGAGAATTATC ATGTCAAATGTATCAGCGATCTGCTGACATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCCTGACATGCA TGATTGCTCATGTTTGTGAACTCGTTCCAGGTGATTTCGTCCATGTTATTGGGGATGCACATGTTTACCACAATCATGTG CGGCCTTTGCAGGAGCAGCTTCTTAACCTACCTAAACCTTTTCCTACTTTGAAGATAAATTCAGAGAAGAAAGATATAGA CTCTTTTGTAGCTGCTGATTTCAAGCTTGTAGGCTATAATCCTCACCAGAAGATTGAGATGAAGATGGCAGTTTAA
Protein sequence (LotjaGi1g1v0565200.3) extracted from Lotus japonicus Gifu v1.2 Proteins.
MMTGDSFVVSSGNGNGSINPLPNLQRTYQVVVAATKDMGIGKDGKLPWRLFTDLKFFKEITTATSDPGKKNAIVMGRKTW ESIPLKYRPLPGRLNVVLTRSGSFDIGTAENVVICGSISSALELLAASPYCLSIEKVFVIGGGQIFREVLNAPGCEAIHF TEIHASIECDTFMPPVDSTKYQLWYSSFPKVENDIRYSFATYVRVQSSAAESLSQNTDPLFDNNSDSLKFEVQNFDFLPE MILQRHEEYMYLRLIQEIISEGTTKDDRTGTGTLSKFGCQMRFNLRRSFPLLTTKKVFWRGVVEELLWFISGSTNAKVLQ EKGIHIWDGNASREYLDSIGLTEREEGDLGPVYGFQWRHFGARYSDMHKDYSGQGYDQLLDVINKIKHNPNDRRIILSAW NPVDLKLMALPPCHMFAQFFVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCELVPGDFVHVIGDAHVYHNHV RPLQEQLLNLPKPFPTLKINSEKKDIDSFVAADFKLVGYNPHQKIEMKMAV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| SUPERFAMILY | 1 | 204 | 204 | 7.07E-59 | ||
| PIRSF | 13 | 531 | 519 | 1.5E-257 | ||
| Gene3D | 15 | 205 | 191 | 1.9E-59 | ||
| PANTHER | 24 | 531 | 508 | 1.2E-288 | – | |
| PANTHER | 24 | 531 | 508 | 1.2E-288 | – | |
| ProSiteProfiles | 27 | 204 | 178 | 51.57 | ||
| Pfam | 29 | 204 | 176 | 2.3E-39 | ||
| CDD | 31 | 203 | 173 | 1.95387E-60 | ||
| ProSitePatterns | 39 | 61 | 23 | - | ||
| SUPERFAMILY | 236 | 531 | 296 | 1.7E-137 | ||
| Gene3D | 237 | 531 | 295 | 3.5E-142 | ||
| Hamap | 248 | 531 | 284 | 35.821 | ||
| TIGRFAM | 250 | 531 | 282 | 8.2E-104 | ||
| Pfam | 250 | 531 | 282 | 2.7E-112 | ||
| CDD | 251 | 484 | 234 | 7.02631E-121 | ||
| PRINTS | 289 | 310 | 22 | 7.0E-53 | ||
| PRINTS | 382 | 401 | 20 | 7.0E-53 | ||
| ProSitePatterns | 393 | 421 | 29 | - | ||
| PRINTS | 408 | 423 | 16 | 7.0E-53 | ||
| PRINTS | 426 | 452 | 27 | 7.0E-53 | ||
| PRINTS | 464 | 481 | 18 | 7.0E-53 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. | ||
| Molecular function | Thymidylate synthase activity | Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. | ||
| Biological process | DTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). | ||
| Biological process | One-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. | ||
| Biological process | Tetrahydrofolate biosynthetic process | The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi1g1v0565200.3, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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