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AP endonucleases family 1 profile.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Nuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids. | ||
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: exodeoxyribonuclease-like [Glycine max] gi|356508768|ref|XP_003523126.1| | 11 | ||
| – | PREDICTED: DNA-(apurinic or apyrimidinic site) lyase 2-like [Glycine max] gi|356502118|ref|XP_003519868.1| | 11 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: apurinic endonuclease-redox protein-like [Glycine max] gi|356537505|ref|XP_003537267.1| | 21 | ||
| – | DNA-(apurinic or apyrimidinic site) lyase; TAIR: AT3G48425.1 DNAse I-like superfamily protein; Swiss-Prot: sp|Q5XF07|APE1L_ARATH DNA-(apurinic or apyrimidinic site) lyase; TrEMBL-Plants: tr|I1JXF2|I1JXF2_SOYBN DNA-(apurinic or apyrimidinic site) lyase; Found in the gene: LotjaGi1g1v0231200 | 12 | ||
| – | DNA-(apurinic or apyrimidinic site) lyase; TAIR: AT4G36050.3 endonuclease/exonuclease/phosphatase family protein; Swiss-Prot: sp|F4JNY0|APE2_ARATH DNA-(apurinic or apyrimidinic site) lyase 2; TrEMBL-Plants: tr|A0A151QUY4|A0A151QUY4_CAJCA DNA-(apurinic or apyrimidinic site) lyase; Found in the gene: LotjaGi4g1v0128100 | 13 | ||
| – | DNA-(apurinic or apyrimidinic site) lyase; TAIR: AT2G41460.1 apurinic endonuclease-redox protein; Swiss-Prot: sp|P45951|ARP_ARATH DNA-(apurinic or apyrimidinic site) lyase, chloroplastic; TrEMBL-Plants: tr|K7K9G6|K7K9G6_SOYBN DNA-(apurinic or apyrimidinic site) lyase; Found in the gene: LotjaGi5g1v0135000 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |