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GSH_gloB: hydroxyacylglutathione hydrolase
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Hydroxyacylglutathione hydrolase activity | Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. | ||
Biological process | Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione | The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Hydroxyacylglutathione hydrolase [Medicago truncatula] gi|357490351|ref|XP_003615463.1| | 13 | ||
– | Glyoxalase 2-4 [Theobroma cacao] gi|508712917|gb|EOY04814.1| | 12 | ||
– | PREDICTED: probable hydroxyacylglutathione hydrolase 2, chloroplast-like [Glycine max] gi|356545443|ref|XP_003541152.1| | 15 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT3G10850.1 Metallo-hydrolase/oxidoreductase superfamily protein; Swiss-Prot: sp|O24496|GLO2C_ARATH Hydroxyacylglutathione hydrolase cytoplasmic; TrEMBL-Plants: tr|I3SRG4|I3SRG4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0129000 | 15 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.2 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|C6TKG9|C6TKG9_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0032100 | 15 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I1MD49|I1MD49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0032100 | 16 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I1MD49|I1MD49_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0032100 | 16 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I1M574|I1M574_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0032100 | 16 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I3SKI5|I3SKI5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0500500 | 18 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I3SKI5|I3SKI5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0500500 | 18 | ||
– | Hydroxyacylglutathione hydrolase; TAIR: AT1G06130.1 glyoxalase 2-4; Swiss-Prot: sp|Q8LDW8|GLO2D_ARATH Probable hydroxyacylglutathione hydrolase 2, chloroplastic; TrEMBL-Plants: tr|I3SKI5|I3SKI5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0500500 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd07723 | CDD | 1 | 9.09 |