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Field | Value |
---|---|
Namespace | Cellular component |
Short description | Chromatin |
Full defintion | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
Subterm of |
The relationship of GO:0000785 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0000785, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
---|---|
GOC | elh |
PMID | Characterization of the RNA content of chromatin. Genome Res. 2010 Jul; 20 (7): 899–907.PMID: 20404130 Noncoding RNA (ncRNA) constitutes a significant portion of the mammalian transcriptome. Emerging evidence suggests that it regulates gene expression in cis or trans by modulating the chromatin structure. To uncover the functional role of ncRNA in chromatin organization, we deep sequenced chromatin-associated RNAs (CARs) from human fibroblast (HF) cells. This resulted in the identification of 141 intronic regions and 74 intergenic regions harboring CARs. The intronic and intergenic CARs show significant conservation across 44 species of placental mammals. Functional characterization of one of the intergenic CARs, Intergenic10, revealed that it regulates gene expression of neighboring genes through modulating the chromatin structure in cis. Our data suggest that ncRNA is an integral component of chromatin and that it may regulate various biological functions through fine-tuning of the chromatin architecture. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | HMG-Y-related protein A [Medicago truncatula] gi|357460891|ref|XP_003600727.1| | 4 | ||
– | AT-hook protein 1 [Zea mays] gi|226532898|ref|NP_001149717.1| | 4 | ||
– | High mobility group protein [Canavalia gladiata] gi|1181589|dbj|BAA11766.1| | 4 | ||
– | HMGI/Y [Pisum sativum] gi|899367|emb|CAA61747.1| | 4 | ||
– | HMG-Y-related protein A; TAIR: AT1G14900.1 high mobility group A; Swiss-Prot: sp|Q00423|HMGYA_SOYBN HMG-Y-related protein A; TrEMBL-Plants: tr|A0A1J7HLR9|A0A1J7HLR9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0092300 | 4 | ||
– | AT hook motif DNA-binding family protein; TAIR: AT2G33620.1 AT hook motif DNA-binding family protein; Swiss-Prot: sp|O22812|AHL10_ARATH AT-hook motif nuclear-localized protein 10; TrEMBL-Plants: tr|V7AUS6|V7AUS6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0569400 | 4 | ||
– | Histone H1; TAIR: AT1G48620.1 high mobility group A5; Swiss-Prot: sp|Q9FYS5|HMGYA_MAIZE HMG-Y-related protein A; TrEMBL-Plants: tr|V7CTB3|V7CTB3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0198500 | 4 | ||
– | Transcription factor jumonji domain-containing protein, putative isoform 2; TAIR: AT3G18035.2 winged-helix DNA-binding transcription factor family protein; Swiss-Prot: sp|P52927|HMGA2_MOUSE High mobility group protein HMGI-C; TrEMBL-Plants: tr|A0A061G1U9|A0A061G1U9_THECC Transcription factor jumonji domain-containing protein, putative isoform 1; Found in the gene: LotjaGi3g1v0261700_LC | 4 | ||
– | HMG-Y-related protein A; TAIR: AT1G14900.1 high mobility group A; Swiss-Prot: sp|Q00423|HMGYA_SOYBN HMG-Y-related protein A; TrEMBL-Plants: tr|A0A1J7HLR9|A0A1J7HLR9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0056500 | 4 | ||
– | HMG-Y-related A; TAIR: AT1G14900.1 high mobility group A; Swiss-Prot: sp|Q00423|HMGYA_SOYBN HMG-Y-related protein A; TrEMBL-Plants: tr|G7J9E3|G7J9E3_MEDTR Linker histone H1 and h5 family protein; Found in the gene: LotjaGi6g1v0056600 | 4 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Biological process | Regulation of transcription, DNA-templated | 1 | 10.00 |