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GO:0008568

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Microtubule-severing ATPase activity
Full defintion Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.
Subterm of

Relationships

The relationship of GO:0008568 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
EC3.6.4.3
PMID
Cellular Samurai: katanin and the severing of microtubules.Quarmby L
J Cell Sci. 2000 Aug; 113 ( Pt 16) (): 2821–7.PMID: 10910766

Recent biochemical studies of the AAA ATPase, katanin, provide a foundation for understanding how microtubules might be severed along their length. These in vitro studies are complemented by a series of recent reports of direct in vivo observation of microtubule breakage, which indicate that the in vitro phenomenon of catalysed microtubule severing is likely to be physiological. There is also new evidence that microtubule severing by katanin is important for the production of non-centrosomal microtubules in cells such as neurons and epithelial cells. Although it has been difficult to establish the role of katanin in mitosis, new genetic evidence indicates that a katanin-like protein, MEI-1, plays an essential role in meiosis in C. elegans. Finally, new proteins involved in the severing of axonemal microtubules have been discovered in the deflagellation system of Chlamydomonas.

Associated Lotus transcripts 5

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj3g3v2247050.1
– PREDICTED: katanin p60 ATPase-containing subunit A1-like [Cicer arietinum] gi|502147679|ref|XP_004506874.1|
GO terms
3
LotjaGi3g1v0361300.2
– Katanin p60 ATPase-containing subunit A1; TAIR: AT1G80350.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9SEX2|KTNA1_ARATH Katanin p60 ATPase-containing subunit A1; TrEMBL-Plants: tr|A0A0S3T0H0|A0A0S3T0H0_PHAAN Katanin p60 ATPase-containing subunit A1; Found in the gene: LotjaGi3g1v0361300
GO terms
3
LotjaGi3g1v0361300.4
– Katanin p60 ATPase-containing subunit A1; TAIR: AT1G80350.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9SEX2|KTNA1_ARATH Katanin p60 ATPase-containing subunit A1; TrEMBL-Plants: tr|A0A0S3T0H0|A0A0S3T0H0_PHAAN Katanin p60 ATPase-containing subunit A1; Found in the gene: LotjaGi3g1v0361300
GO terms
3
LotjaGi3g1v0361300.5
– Katanin p60 ATPase-containing subunit A1; TAIR: AT1G80350.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9SEX2|KTNA1_ARATH Katanin p60 ATPase-containing subunit A1; TrEMBL-Plants: tr|V7ASY5|V7ASY5_PHAVU Katanin p60 ATPase-containing subunit A1; Found in the gene: LotjaGi3g1v0361300
GO terms
3
LotjaGi3g1v0361300.6
– Katanin p60 ATPase-containing subunit A1; TAIR: AT1G80350.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9SEX2|KTNA1_ARATH Katanin p60 ATPase-containing subunit A1; TrEMBL-Plants: tr|I1KH58|I1KH58_SOYBN Katanin p60 ATPase-containing subunit A1; Found in the gene: LotjaGi3g1v0361300
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0051013
Biological process Microtubule severing 1 20.00