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IPR000118

Source: InterPro

Description

IPR000118 is a Granulin.

<p>Metazoan granulins [[cite:PUB00004773]] are a family of cysteine-rich peptides of about 6 Kd which may have multiple biological activity. A precursor protein (known as acrogranin) potentially encodes seven different forms of granulin (grnA to grnG) which are probably released by post-translational proteolytic processing. Granulins are evolutionary related to PMP-D1, a peptide extracted from the pars intercerebralis of migratory locusts [[cite:PUB00001409]]. A schematic representation of the structure of a granulin is shown below:</p> <pre> xxxCxxxxxCxxxxxCCxxxxxxxxCCxxxxxxCCxxxxxCCxxxxxCxxxxxxCx 'C': conserved cysteine probably involved in a disulphide bond. </pre> <p>In plants a granulin domain is often associated with the C terminus of cysteine proteases belong to the MEROPS peptidase family C1, subfamily C1A (papain).</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj1g3v2139680.1
– PREDICTED: oryzain alpha chain-like [Cicer arietinum] gi|502131381|ref|XP_004500967.1|
Domains
32
Lj5g3v0294860.1
– PREDICTED: cysteine proteinase RD21a-like [Cicer arietinum] gi|502125689|ref|XP_004499026.1|
Domains
30
Lj5g3v2133770.1
– PREDICTED: cysteine proteinase RD21a-like isoform X1 [Cicer arietinum] gi|502120445|ref|XP_004496965.1|
Domains
30
LotjaGi1g1v0423400.1
– Cysteine protease family protein; TAIR: AT1G09850.1 xylem bark cysteine peptidase 3; Swiss-Prot: sp|Q9LT78|RD21C_ARATH Probable cysteine protease RD21C; TrEMBL-Plants: tr|A0A1J7IIQ9|A0A1J7IIQ9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0423400
Domains
34
LotjaGi5g1v0030300.1
– Cysteine proteinase; TAIR: AT1G47128.1 Granulin repeat cysteine protease family protein; Swiss-Prot: sp|P43297|RD21A_ARATH Cysteine proteinase RD21A; TrEMBL-Plants: tr|A0A1J7IKX0|A0A1J7IKX0_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0030300
Domains
33
LotjaGi5g1v0329500.1
– Cysteine protease, putative; TAIR: AT5G43060.1 Granulin repeat cysteine protease family protein; Swiss-Prot: sp|Q9FMH8|RD21B_ARATH Probable cysteine protease RD21B; TrEMBL-Plants: tr|A0A1J7HJC8|A0A1J7HJC8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0329500
Domains
33
LotjaGi6g1v0322400.1
– Cysteine protease; TAIR: AT1G09850.1 xylem bark cysteine peptidase 3; Swiss-Prot: sp|P25776|ORYA_ORYSJ Oryzain alpha chain; TrEMBL-Plants: tr|A0A151S6D2|A0A151S6D2_CAJCA Cysteine proteinase RD21a; Found in the gene: LotjaGi6g1v0322400
Domains
35

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 14.29