Description

IPR001216 is a Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site.

<p>Cysteine synthase ([ec:4.2.99.8]) (CSase) is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulphide with the concomitant release of acetic acid [[cite:PUB00001662]]. In bacteria such as Escherichia coli, two such forms of the enzyme are known (genes cysK and cysM). In plants there are also two forms, one located in the cytoplasm and the other in chloroplasts.</p> <p>Cystathionine beta-synthase ([ec:4.2.1.22]) catalyses the first irreversible step in homocysteine transulphuration, the conjugation of homocysteine and serine forming cystathionine. Like Csase it is a pyridoxal-phosphate dependent enzyme [[cite:PUB00002710]].</p> <p>Both enzymes are evolutionary related. The pyridoxal-phosphate attaches to the lysine residue found in the N-terminal section of these enzymes; the sequence around the lysine residue is highly conserved.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: